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Author Details
Full Name
Mathieu Laplante
Affiliation
Centre de recherche sur le cancer de l'Universite Laval, Universite Laval
ORCID
Career Start Year
2003
Papers
69
H Index
35
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36535626
DEPTOR loss impairs brown adipocyte development in vitro but has limited impacts in mice.
Mol Metab
2023
35017517
The transcription factor hepatocyte nuclear factor 4A acts in the intestine to promote white adipose tissue energy storage.
Nat Commun
2022
36536135
mTORC1 takes control of lysosomal lipid breakdown.
Nat Metab
2022
35033724
Adipocyte-specific Nos2 deletion improves insulin resistance and dyslipidemia through brown fat activation in diet-induced obese mice.
Mol Metab
2022
33196296
Control of adipogenic commitment by a STAT3-VSTM2A axis.
Am J Physiol Endocrinol Metab
2021
35419475
ZNF768: controlling cellular senescence and proliferation with ten fingers.
Mol Cell Oncol
2021
34439288
ZNF768 Expression Associates with High Proliferative Clinicopathological Features in Lung Adenocarcinoma.
Cancers (Basel)
2021
34404770
ZNF768 links oncogenic RAS to cellular senescence.
Nat Commun
2021
34541875
Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice.
Am J Physiol Endocrinol Metab
2021
34135321
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
Nat Commun
2021
33284090
Metabolic responses to intermittent hypoxia are regulated by sex and estradiol in mice.
Am J Physiol Endocrinol Metab
2021
32640840
Critical importance of dietary methionine and choline in the maintenance of lung homeostasis during normal and cigarette smoke exposure conditions.
Am J Physiol Lung Cell Mol Physiol
2020
30702343
Pharmacological activation of liver X receptor during cigarette smoke exposure adversely affects alveolar macrophages and pulmonary surfactant homeostasis.
Am J Physiol Lung Cell Mol Physiol
2019
31767170
The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis.
Mol Metab
2019
29969188
DEPTOR modulates activation responses in CD4<sup>+</sup> T cells and enhances immunoregulation following transplantation.
Am J Transplant
2019
31391339
The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis.
JCI Insight
2019
30862908
HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide.
Sci Rep
2019
30770439
PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin.
Proc Natl Acad Sci U S A
2019
29549139
Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome.
Sci Immunol
2018
29897294
DEPTOR at the Nexus of Cancer, Metabolism, and Immunity.
Physiol Rev
2018
30604855
Lung cancer susceptibility genetic variants modulate HOXB2 expression in the lung.
Int J Dev Biol
2018
30317185
Cytokines promote lipolysis in 3T3-L1 adipocytes through induction of NADPH oxidase 3 expression and superoxide production.
J Lipid Res
2018
29496744
Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure.
Diabetes
2018
28052263
Amplification of Adipogenic Commitment by VSTM2A.
Cell Rep
2017
28462079
Loss of hepatic DEPTOR alters the metabolic transition to fasting.
Mol Metab
2017
28270767
A Phosphorylatable Sphingosine Analog Induces Airway Smooth Muscle Cytostasis and Reverses Airway Hyperresponsiveness in Experimental Asthma.
Front Pharmacol
2017
29138472
Functional characterization of the Ucp1-associated oxidative phenotype of human epicardial adipose tissue.
Sci Rep
2017
26880548
Involvement of the Acyl-CoA binding domain containing 7 in the control of food intake and energy expenditure in mice.
Elife
2016
27876792
mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.
Sci Rep
2016
27624942
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway.
Nat Commun
2016
27143559
Metabolic activity of brown, "beige," and white adipose tissues in response to chronic adrenergic stimulation in male mice.
Am J Physiol Endocrinol Metab
2016
27097662
DEPTOR in POMC neurons affects liver metabolism but is dispensable for the regulation of energy balance.
Am J Physiol Regul Integr Comp Physiol
2016
25159114
DEP domain-containing mTOR-interacting protein in the rat brain: distribution of expression and potential implication.
J Comp Neurol
2015
26909318
Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity.
Mol Metab
2015
26185979
The Roles of mTOR Complexes in Lipid Metabolism.
Annu Rev Nutr
2015
25681456
In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis.
FASEB J
2015
24936254
Interrelationships between ghrelin, insulin and glucose homeostasis: Physiological relevance.
World J Diabetes
2014
25352671
A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver.
Proc Natl Acad Sci U S A
2014
24740015
Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide.
PLoS One
2014
23641065
Regulation of mTORC1 and its impact on gene expression at a glance.
J Cell Sci
2013
23658371
A comparative perspective on lipid storage in animals.
J Cell Sci
2013
22129599
mTOR Signaling.
Cold Spring Harb Perspect Biol
2012
22883231
DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.
Cell Metab
2012
22449814
Connecting mTORC1 signaling to SREBP-1 activation.
Curr Opin Lipidol
2012
22500797
mTOR signaling in growth control and disease.
Cell
2012
22410287
Insulin stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTOR pathway.
Mol Cell Endocrinol
2012
19766266
Preliminary report: pharmacologic 11beta-hydroxysteroid dehydrogenase type 1 inhibition increases hepatic fat oxidation in vivo and expression of related genes in rats fed an obesogenic diet.
Metabolism
2010
21179166
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing.
Nature
2010
20167806
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis.
Proc Natl Acad Sci U S A
2010
18971352
Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat.
Am J Physiol Regul Integr Comp Physiol
2009
1 - 50 of 69
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