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Author Details

C David Allis
The Rockefeller University
1974
399
154
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36264143A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition.Cancer Discov2023
37808786Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation.bioRxiv2023
37491148Histone bivalency regulates the timing of cerebellar granule cell development.Genes Dev2023
37626123MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.Nat Commun2023
37650454Correction: Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons.J Cell Sci2023
37261974MLL3 regulates the <i>CDKN2A</i> tumor suppressor locus in liver cancer.Elife2023
36778390Histone bivalency regulates the timing of cerebellar granule cell development.bioRxiv2023
36516747Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation.Cell Rep2022
32711094HAT discovery: Heading toward an elusive goal with a key biological assist.Biochim Biophys Acta Gene Regul Mech2021
33649601Oncohistone mutations enhance chromatin remodeling and alter cell fates.Nat Chem Biol2021
33619101Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation.Proc Natl Acad Sci U S A2021
34613815Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.Sci Transl Med2021
34580064Histone H1 Mutations in Lymphoma: A Link(er) between Chromatin Organization, Developmental Reprogramming, and Cancer.Cancer Res2021
33986537Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands.Nat Genet2021
34002060The language of chromatin modification in human cancers.Nat Rev Cancer2021
33472068HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies.Cell Rep2021
33412588A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies.Nucleic Acids Res2021
32396861Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response.Cancer Cell2020
33067396Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.Proc Natl Acad Sci U S A2020
32935098Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors.bioRxiv2020
32989154Loss of UTX/KDM6A and the activation of FGFR3 converge to regulate differentiation gene-expression programs in bladder cancer.Proc Natl Acad Sci U S A2020
32699416Histone H3.3 phosphorylation amplifies stimulation-induced transcription.Nature2020
32472103In situ chromatin interactomics using a chemical bait and trap approach.Nat Chem2020
32268116ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase.Cell Metab2020
31068593Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease.Nat Commun2019
31611394PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor.Proc Natl Acad Sci U S A2019
31485078The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.Nature2019
29395068Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation.Mol Cell2018
30217363Pursuing the Secrets of Histone Proteins: An Amazing Journey with a Remarkable Supporting Cast.Cell2018
30208392Genetics, Biochemistry, and "Simple" Organisms Converge to Unlock Secrets in Histone Biology: The 2018 Albert Lasker Basic Medical Research Award.JAMA2018
29847798NMDA Receptor Activation Underlies the Loss of Spinal Dorsal Horn Neurons and the Transition to Persistent Pain after Peripheral Nerve Injury.Cell Rep2018
30374167Structure-guided development of YEATS domain inhibitors by targeting Ï¿-Ï¿-Ï¿ stacking.Nat Chem Biol2018
30315258ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup.Nat Commun2018
29358330Histone variant H3.3-mediated chromatin remodeling is essential for paternal genome activation in mouse preimplantation embryos.J Biol Chem2018
29547264Reading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum".ACS Chem Biol2018
29662175Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.Nat Cell Biol2018
29395070Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs.Mol Cell2018
29395069Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome.Mol Cell2018
27864305Oncogenic Mechanisms of Histone H3 Mutations.Cold Spring Harb Perspect Med2017
28138149SWI/SNF complex in cancer.Nat Genet2017
28108335Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells.J Allergy Clin Immunol2017
28241141ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.Nature2017
29030587NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression.Nat Commun2017
28536244Opinion: On being an advisor to today's junior scientists.Proc Natl Acad Sci U S A2017
28770850Elsässer et al. reply.Nature2017
28767641ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference.Nature2017
28823556Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition.Cell2017
27924077Metabolic regulation of gene expression through histone acylations.Nat Rev Mol Cell Biol2017
28067913Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.Nat Genet2017
27103431YEATS2 is a selective histone crotonylation reader.Cell Res2016
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Collaborators

University of Pennsylvania
Co-authored papers 25
University of Virginia
Co-authored papers 23
University of Virginia
Co-authored papers 20
University of North Carolina
Co-authored papers 18
the Rockefeller University
Co-authored papers 17
Memorial Sloan-Kettering Cancer Center
Co-authored papers 16
Penn Epigenetics Institute, Perelman School of Medicine
Co-authored papers 13
Princeton University
Co-authored papers 12
Purdue University
Co-authored papers 10
Co-authored papers 9
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 8
Memorial Sloan Kettering Cancer Center
Co-authored papers 8
The Rockefeller University
Co-authored papers 7
Co-authored papers 7
Co-authored papers 7
HHMI/NYU Langone School of Medicine
Co-authored papers 6
Co-authored papers 6
EpiCypher Inc.
Co-authored papers 6
Institut Curie, PSL Research University, CNRS UMR 5, INSERM U934
Co-authored papers 6
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University of Sassari
Co-authored papers 5
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University College London
Co-authored papers 4
Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University
Co-authored papers 4
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 4
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 4
Meyer Cancer Center
Co-authored papers 4
Van Andel Institute
Co-authored papers 4
National Cancer Institute, National Institutes of Health
Co-authored papers 4