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Author Details

Yoshiaki Ito
Tokyo Medical and Dental University (TMDU)
1987
282
77
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36766749RUNX3 in Stem Cell and Cancer Biology.Cells2023
37243602Protocol for identification and validation of IGF2BP1 target genes in pluripotent human embryonic carcinoma cells.STAR Protoc2023
37400551RUNX3 inactivates oncogenic MYC through disruption of MYC/MAX complex and subsequent recruitment of GSK3β-FBXW7 cascade.Commun Biol2023
37355533Identifying Adult Stomach Tissue Stem/Progenitor Cells Using the Iqgap3-2A-CreERT2 Mouse.Methods Mol Biol2023
36509142RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs.J Biol Chem2023
35074568A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach.Cell Mol Gastroenterol Hepatol2022
35511868A Runx1-enhancer Element eR1 Identified Lineage Restricted Mammary Luminal Stem Cells.Stem Cells2022
35801715Identification of responsible amino acid residues in staphylococcal superantigen-like 12 for the activation of mast cells.Genes Cells2022
35668101Foxf2 represses bone formation via Wnt2b/β-catenin signaling.Exp Mol Med2022
36217548Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer.iScience2022
35163588The <i>H. pylori</i> CagA Oncoprotein Induces DNA Double Strand Breaks through Fanconi Anemia Pathway Downregulation and Replication Fork Collapse.Int J Mol Sci2022
33293280Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair.Gut2021
34944780Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids.Cancers (Basel)2021
34391772Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus.Gastroenterology2021
34126195Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids.Cancer Lett2021
34230481Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis.Nat Commun2021
33315201MicroRNA Expression Profiling, Target Identification, and Validation in Chondrocytes.Methods Mol Biol2021
33444684Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell lines.Gene2021
32479258<i>Lin28a/let-7</i> pathway modulates the <i>Hox</i> code via <i>Polycomb</i> regulation during axial patterning in vertebrates.Elife2020
31937549DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia.Gut2020
31926544The RUNX1 Enhancer Element eR1: A Versatile Marker for Adult Stem Cells.Mol Cells2020
33115981K-Ras-Activated Cells Can Develop into Lung Tumors When Runx3-Mediated Tumor Suppressor Pathways Are Abrogated.Mol Cells2020
32926445The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA.EMBO J2020
32671057<i>In vitro</i> Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System.Front Cell Dev Biol2020
32209656Inflammatory and mitogenic signals drive interleukin 23 subunit alpha (IL23A) secretion independent of IL12B in intestinal epithelial cells.J Biol Chem2020
30535344Functional relationship between p53 and RUNX proteins.J Mol Cell Biol2019
31213005FBXW5 Promotes Tumorigenesis and Metastasis in Gastric Cancer via Activation of the FAK-Src Signaling Pathway.Cancers (Basel)2019
31015486RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction-point.Nat Commun2019
31160553Wwp2 maintains cartilage homeostasis through regulation of Adamts5.Nat Commun2019
29074538TGFβ Promotes Genomic Instability after Loss of RUNX3.Cancer Res2018
29890655High-Risk Human Papillomaviral Oncogenes E6 and E7 Target Key Cellular Pathways to Achieve Oncogenesis.Int J Mol Sci2018
30110632RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair.Cell Rep2018
30530754Ablation of miR-146b in mice causes hematopoietic malignancy.Blood Adv2018
28324176Bhlha9 regulates apical ectodermal ridge formation during limb development.J Bone Miner Metab2018
29581836RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer.Oncotarget2018
27993989The transcription factor mohawk homeobox regulates homeostasis of the periodontal ligament.Development2017
28356515Identification of targets of tumor suppressor microRNA-34a using a reporter library system.Proc Natl Acad Sci U S A2017
28299675A Regulatory Role for RUNX1, RUNX3 in the Maintenance of Genomic Integrity.Adv Exp Med Biol2017
28299665Roles of RUNX in Solid Tumors.Adv Exp Med Biol2017
28119527RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC.Leukemia2017
28467430Analysis of transcription factors expressed at the anterior mouse limb bud.PLoS One2017
29344546RUNX3 loss turns on the dark side of TGF-beta signaling.Oncoscience2017
28916727Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis.J Biol Chem2017
28552403Reply.Gastroenterology2017
28846108Runx3 plays a critical role in restriction-point and defense against cellular transformation.Oncogene2017
27670082Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice.Gastroenterology2017
26745853RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity.Blood Cancer J2016
26364597RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer.Oncogene2016
27421133CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer.Oncotarget2016
27527664Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.Nat Commun2016
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Collaborators

Katsuya Shigesada
Institute for Virus Research, Kyoto University
Co-authored papers 28
Gary S Stein
University of Vermont
Co-authored papers 8
Andre J van Wijnen
Co-authored papers 7
Tuan Zea Tan
Cancer Science Institute of Singapore, National University of Singapore
Co-authored papers 7
Woo Young Kim
Westchester Medical Center
Co-authored papers 7
Masayuki Yamamoto
Tohoku University Graduate School of Medicine, Tohoku University
Co-authored papers 6
Jane B Lian
University of Vermont
Co-authored papers 6
Henry Yang
Cancer Science Institute of Singapore, National University of Singapore
Co-authored papers 5
Lavina Sierra Tay
Genome Institute of Singapore
Co-authored papers 4
Marie Loh
Lee Kong Chian School of Medicine, Nanyang Technological University
Co-authored papers 4
Takuro Nakamura
Tohoku University Graduate School of Medicine
Co-authored papers 3
Milton H Werner
Inhibikase Therapeutics Inc.
Co-authored papers 3
Daniel G Tenen
Harvard Stem Cell Institute, Harvard Medical School
Co-authored papers 3
Yuka Kanno
Co-authored papers 3
Vineet Gupta
Purdue University
Co-authored papers 2
Wendy H Raskind
University of Washington School of Medicine
Co-authored papers 2
Atsushi Inoue
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Sumio Sugano
Co-authored papers 1
Guy Sauvageau
Universite de Montreal
Co-authored papers 1
Jeffrey L Wrana
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital
Co-authored papers 1
Mark Donowitz
Johns Hopkins University School of Medicine
Co-authored papers 1
Nikolajs Zeps
Queensland University of Technology
Co-authored papers 1
Lewis C Cantley
Co-authored papers 1
Cornelis J H van de Velde
Leiden University Medical Center: Leids Universitair Medisch Centrum.
Co-authored papers 1
Brian T Chait
The Rockefeller University
Co-authored papers 1
Jeremy A Squire
University of Sao Paulo
Co-authored papers 1
Kengo Kinoshita
Co-authored papers 1
Hye Ryun Kim
Yonsei Cancer Center, Yonsei University College of Medicine
Co-authored papers 1
Hoguen Kim
Korea Advanced Institute of Science and Technology (KAIST)
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Release 1.2