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Author Details

Volker D??tsch
Institute for Biophysical Chemistry, Goethe-University
1995
270
64
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37224528A conserved motif in the disordered linker of human MLH1 is vital for DNA mismatch repair and its function is diminished by a cancer family mutation.Nucleic Acids Res2023
37488194Correction: A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1.Oncogene2023
37750869ASPP2 binds to hepatitis C virus NS5A protein via an SH3 domain/PxxP motif-mediated interaction and potentiates infection.J Gen Virol2023
37999976An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant.Cell Rep2023
38045926<i>In vitro</i> characterization of the phage lysis protein MS2-L.Microbiome Res Rep2023
37828008DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.Cell Death Dis2023
37777570Fuzzy interactions between the auto-phosphorylated C-terminus and the kinase domain of CK1δ inhibits activation of TAp63α.Sci Rep2023
37772190Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues.JACS Au2023
37311907E. coli "Stablelabel" S30 lysate for optimized cell-free NMR sample preparation.J Biomol NMR2023
37072394Disease-related p63 DBD mutations impair DNA binding by distinct mechanisms and varying degree.Cell Death Dis2023
34759346A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1.Oncogene2022
35773595Cell-Free Expression of GPCRs into Nanomembranes for Functional and Structural Studies.Methods Mol Biol2022
35717996Biochemical Characterization of Cell-free Synthesized Human β<sub>1</sub> Adrenergic Receptor Cotranslationally Inserted into Nanodiscs.J Mol Biol2022
35717504Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.Cell Death Differ2022
35353987Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes.Mol Cell2022
35935506Transfer mechanism of cell-free synthesized membrane proteins into mammalian cells.Front Bioeng Biotechnol2022
35921875Cotranslational assembly of membrane protein/nanoparticles in cell-free systems.Biochim Biophys Acta Biomembr2022
36261000Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis.Cell Rep2022
35314772Structural diversity of p63 and p73 isoforms.Cell Death Differ2022
35246516Enhanced pro-apoptosis gene signature following the activation of TAp63α in oocytes upon γ irradiation.Cell Death Dis2022
35089562Applications of Cell-Free Synthesized Membrane Protein Precipitates.Methods Mol Biol2022
35112738Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.EMBO J2022
32975353In-Cell NMR Spectroscopy of Functional Riboswitch Aptamers in Eukaryotic Cells.Angew Chem Int Ed Engl2021
33576509The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63-branched ubiquitin chains.EMBO J2021
33769048Demonstrating Ligandability of the LC3A and LC3B Adapter Interface.J Med Chem2021
33572532Isoform-Specific Roles of Mutant p63 in Human Diseases.Cancers (Basel)2021
33723372Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy.Cell Death Differ2021
34131311Mechanisms of quality control differ in male and female germ cells.Cell Death Differ2021
34299007A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1.Int J Mol Sci2021
33980013Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders.J Med Chem2021
34085264Screening Methods for Cell-Free Synthesized GPCR/Nanoparticle Samples.Methods Mol Biol2021
33452256The p63 C-terminus is essential for murine oocyte integrity.Nat Commun2021
33244868Membrane insertion mechanism and molecular assembly of the bacteriophage lysis toxin ΦX174-E.FEBS J2021
30990354An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5.Autophagy2020
31937588Oxygen-dependent asparagine hydroxylation of the ubiquitin-associated (UBA) domain in Cezanne regulates ubiquitin binding.J Biol Chem2020
31732457Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB.Mol Cell2020
31682841A TP63 Mutation Causes Prominent Alopecia with Mild Ectodermal Dysplasia.J Invest Dermatol2020
33287328DNA Damaged Induced Cell Death in Oocytes.Molecules2020
33283784Co-translational Insertion of Membrane Proteins into Preformed Nanodiscs.J Vis Exp2020
32719556p63 uses a switch-like mechanism to set the threshold for induction of apoptosis.Nat Chem Biol2020
32731622Ubiquitination in the ERAD Process.Int J Mol Sci2020
32873634Phosphorylation Control of p53 DNA-Binding Cooperativity Balances Tumorigenesis and Aging.Cancer Res2020
32726587Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.Cell Chem Biol2020
30611423Synthetic Biology-Based Solution NMR Studies on Membrane Proteins in Lipid Environments.Methods Enzymol2019
30225732LILBID and nESI: Different Native Mass Spectrometry Techniques as Tools in Structural Biology.J Am Soc Mass Spectrom2019
31527723TA*p63 and GTAp63 achieve tighter transcriptional regulation in quality control by converting an inhibitory element into an additional transactivation domain.Cell Death Dis2019
31519908Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.Nat Commun2019
30742091Cell cycle arrest in mitosis promotes interferon-induced necroptosis.Cell Death Differ2019
30850703Deletions and loss-of-function variants in TP63 associated with orofacial clefting.Eur J Hum Genet2019
30959416Towards complete polypeptide backbone NH assignment via combinatorial labeling.J Magn Reson2019
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Collaborators

Ivan Dikic
Institute of Biochemistry II, Goethe University Frankfurt
Co-authored papers 21
Stefan Knapp
Institute of Pharmaceutical Chemistry, Goethe University
Co-authored papers 12
Christian Klammt
Salk Institute for Biological Studies
Co-authored papers 11
Vladimir Kirkin
the Institute of Cancer Research London
Co-authored papers 6
Solmaz Sobhanifar
The University of British Columbia
Co-authored papers 6
Charles S Craik
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 6
Gerhard Hummer
Max Planck Institute of Biophysics
Co-authored papers 5
Annie Yang
Co-authored papers 4
Christoph Bock
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 4
Kurt W??thrich
iHuman Institute, ShanghaiTech University
Co-authored papers 3
Han G Brunner
Maastricht University Medical Centre
Co-authored papers 2
Cheryl H Arrowsmith
University of Toronto
Co-authored papers 2
Celia A Schiffer
University of Massachusetts Chan Medical School
Co-authored papers 2
Vladimir Denic
Harvard University
Co-authored papers 2
Thomas F Prisner
Institute of Physical and Theoretical Chemistry, Goethe University Frankfurt
Co-authored papers 2
Sachdev S Sidhu
School of Pharmacy, University of Waterloo
Co-authored papers 2
Zvulun Elazar
Weizmann Institute of Science
Co-authored papers 2
Jeffrey C Hoch
University of Connecticut Health Center
Co-authored papers 2
Simone Fulda
Co-authored papers 2
Arnold J Levine
Simons Center for Systems Biology, Institute for Advanced Study
Co-authored papers 2
Ian G Mills
Queen's University Belfast
Co-authored papers 1
Arianna L Kim
Co-authored papers 1
Daniela Hoeller
Institute of Biochemistry II, Goethe University
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 1
Franck Perez
Institut Curie, PSL Research University, Sorbonne Universite, CNRS
Co-authored papers 1
Tim K??kensh??ner
Institute for Biochemistry and Biology, University of Potsdam
Co-authored papers 1
David Sulzer
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 1
Ernst J Wolvetang
Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Co-authored papers 1
James E Ferrell
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Release 1.2