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Author Details

Claudio Soto
University of Texas McGovern Medical School at Houston
1992
230
78
PMIDPaper TitleJournal TitlePublished Year
36567368PMCA for ultrasensitive detection of prions and to study disease biology.Cell Tissue Res2023
37635939Development of a methodology for large-scale production of prions for biological and structural studies.Front Mol Biosci2023
37863605α-synuclein seed amplification in Parkinson's disease - Authors' reply.Lancet Neurol2023
37424505Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice.EMBO Rep2023
37059509Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study.Lancet Neurol2023
36653527Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid.Nat Protoc2023
36781413Accurate Detection of α-Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson's Disease in the DeNovo Parkinson (DeNoPa) Cohort.Mov Disord2023
36778589Extensive accumulation of misfolded protein aggregates during natural aging and senescence.Front Aging Neurosci2023
36831291Lewy Body-like Pathology and Loss of Dopaminergic Neurons in Midbrain Organoids Derived from Familial Parkinson's Disease Patient.Cells2023
34302479North American and Norwegian Chronic Wasting Disease Prions Exhibit Different Potential for Interspecies Transmission and Zoonotic Risk.J Infect Dis2022
35835859Preventive and therapeutic reduction of amyloid deposition and behavioral impairments in a model of Alzheimer's disease by whole blood exchange.Mol Psychiatry2022
36570526Editorial: Novel mechanisms involved in aging and neurodegeneration: Seeking potential therapeutic targets for neurodegenerative diseases.Front Aging Neurosci2022
36359840Altering Brain Amyloidosis by Intra-Lingual and Extra-Nasal Exposure of Aβ Aggregates.Cells2022
36032402Development of a novel pharmacophore model to screen specific inhibitors for the serine-threonine protein phosphatase calcineurin.Biochem Biophys Rep2022
35015786Correction: Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress.PLoS One2022
35185519Identification of Multicolor Fluorescent Probes for Heterogeneous Aβ Deposits in Alzheimer's Disease.Front Aging Neurosci2022
35120261The clock modulator Nobiletin mitigates astrogliosis-associated neuroinflammation and disease hallmarks in an Alzheimer's disease model.FASEB J2022
35173603Aged Cattle Brain Displays Alzheimer's Disease-Like Pathology and Promotes Brain Amyloidosis in a Transgenic Animal Model.Front Aging Neurosci2022
35264247Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease.Acta Neuropathol Commun2022
33453942Mitochondrial transplant to replenish damaged mitochondria: A novel therapeutic strategy for neurodegenerative diseases?Prog Mol Biol Transl Sci2021
33881777Alpha-Synuclein Oligomers and Neurofilament Light Chain Predict Phenoconversion of Pure Autonomic Failure.Ann Neurol2021
33785065Amyloid pathology arrangements in Alzheimer's disease brains modulate in vivo seeding capability.Acta Neuropathol Commun2021
33893290Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.Nat Commun2021
33864975Multi-scale modeling for systematically understanding the key roles of microglia in AD development.Comput Biol Med2021
33917421Human Endogenous Retroviruses in Glioblastoma Multiforme.Microorganisms2021
34927096Protocol for controlled cortical impact in human cerebral organoids to model traumatic brain injury.STAR Protoc2021
34526562Detection of CWD prions in naturally infected white-tailed deer fetuses and gestational tissues by PMCA.Sci Rep2021
34523135Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.EMBO J2021
34808087Uptake, Retention, and Excretion of Infectious Prions by Experimentally Exposed Earthworms.Emerg Infect Dis2021
34572052Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Familial Parkinson's Disease Patients Display α-Synuclein Pathology and Abnormal Mitochondrial Morphology.Cells2021
34836545Correction to: High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.Acta Neuropathol Commun2021
34685663Modeling Traumatic Brain Injury in Human Cerebral Organoids.Cells2021
34742348High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.Acta Neuropathol Commun2021
34679572Longitudinal Assessment of Tau-Associated Pathology by <sup>18</sup>F-THK5351 PET Imaging: A Histological, Biochemical, and Behavioral Study.Diagnostics (Basel)2021
34830391(De)stabilization of Alpha-Synuclein Fibrillary Aggregation by Charged and Uncharged Surfactants.Int J Mol Sci2021
34319151Prion Dissemination through the Environment and Medical Practices: Facts and Risks for Human Health.Clin Microbiol Rev2021
34236720Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression.Mov Disord2021
34359972Induced Pluripotent Stem Cell-Derived Neural Precursors Improve Memory, Synaptic and Pathological Abnormalities in a Mouse Model of Alzheimer's Disease.Cells2021
33978813Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.Acta Neuropathol2021
34310663Adaptive selection of a prion strain conformer corresponding to established North American CWD during propagation of novel emergent Norwegian strains in mice expressing elk or deer prion protein.PLoS Pathog2021
34002023Transmission of cerebral amyloid pathology by peripheral administration of misfolded Aβ aggregates.Mol Psychiatry2021
34138843Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming.PLoS Biol2021
31591470The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease.Cell Death Differ2020
32025029Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy.Nature2020
31750623The ecology of chronic wasting disease in wildlife.Biol Rev Camb Philos Soc2020
32047275Correction: The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease.Cell Death Differ2020
32047247Bacterial DNA promotes Tau aggregation.Sci Rep2020
31855141Preclinical Detection of Prions in Blood of Nonhuman Primates Infected with Variant Creutzfeldt-Jakob Disease.Emerg Infect Dis2020
33287898Infusion of blood from mice displaying cerebral amyloidosis accelerates amyloid pathology in animal models of Alzheimer's disease.Acta Neuropathol Commun2020
32557811Alpha-Synuclein Oligomers and Neurofilament Light Chain in Spinal Fluid Differentiate Multiple System Atrophy from Lewy Body Synucleinopathies.Ann Neurol2020
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Collaborators

The University of Texas Health Science Center at Houston, McGovern Medical School
Co-authored papers 3
University of Manitoba
Co-authored papers 2
Carnegie Mellon University, The University of Texas Health Science Center at Houston, University of California San Diego
Co-authored papers 1
National Institutes of Health, National Center for Advancing Translational Sciences
Co-authored papers 1
College of Veterinary Medicine, Kansas State University
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Stem Cell Translational Research Center of Tongji Hospital, Tongji University
Co-authored papers 1
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1
Stanford University
Co-authored papers 1
Duke University
Co-authored papers 1
UCSF School of Medicine and San Francisco VA Health Care System
Co-authored papers 1
Zhengzhou University
Co-authored papers 1
Mayo Clinic Rochester
Co-authored papers 1
University of Texas Health Science Center at Houston
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
University of Texas Health Science Center at Houston
Co-authored papers 1
Co-authored papers 1
McGovern Medical School, University of Texas Health Science Center at Houston
Co-authored papers 1
National Center for Biotechnology
Co-authored papers 1
Auburn University
Co-authored papers 1
University of Texas MD Anderson Cancer Center
Co-authored papers 1
Case Western Reserve University
Co-authored papers 1
Indiana University School of Medicine
Co-authored papers 1
Mayo Clinic Jacksonville
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1