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Author Details

Peter J Myler
University of Guelph
1981
273
51
Christopher Churas (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37153643Transition-metal-catalyzed domino reactions of strained bicyclic alkenes.Beilstein J Org Chem2023
37669940Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts.Nat Commun2023
37552766Structure-Guided Discovery of N<sup>5</sup>-CAIR Mutase Inhibitors.Biochemistry2023
37728609Characterization of a family I inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1.Acta Crystallogr F Struct Biol Commun2023
37722671Identification of and Structural Insights into Hit Compounds Targeting <i>N</i>-Myristoyltransferase for <i>Cryptosporidium</i> Drug Development.ACS Infect Dis2023
37185599Immunization with a Trypanosoma cruzi cyclophilin-19 deletion mutant protects against acute Chagas disease in mice.NPJ Vaccines2023
35102892Crystal structure of betaine aldehyde dehydrogenase from Burkholderia pseudomallei.Acta Crystallogr F Struct Biol Commun2022
36412269Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world.Biol Open2022
35924598Crystal structures of glutamyl-tRNA synthetase from Elizabethkingia anopheles and E. meningosepticum.Acta Crystallogr F Struct Biol Commun2022
35921442Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody.Proc Natl Acad Sci U S A2022
36015053Localization of Epigenetic Markers in <i>Leishmania</i> Chromatin.Pathogens2022
36157596Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography.PNAS Nexus2022
35977963Structural characterization of aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa and Neisseria gonorrhoeae.Sci Rep2022
34981772Crystal structure of a putative short-chain dehydrogenase/reductase from Paraburkholderia xenovorans.Acta Crystallogr F Struct Biol Commun2022
34981773Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis.Acta Crystallogr F Struct Biol Commun2022
35245364Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major.J Antimicrob Chemother2022
35234139Crystal structure of an inorganic pyrophosphatase from Chlamydia trachomatis D/UW-3/Cx.Acta Crystallogr F Struct Biol Commun2022
35234140Crystal structure of a hypothetical protein from Giardia lamblia. Corrigendum.Acta Crystallogr F Struct Biol Commun2022
35102893Crystal structure of a short-chain dehydrogenase/reductase from Burkholderia phymatum in complex with NAD.Acta Crystallogr F Struct Biol Commun2022
35102894Crystal structure of a hypothetical protein from Giardia lamblia.Acta Crystallogr F Struct Biol Commun2022
33392924Backbone chemical shift assignments for the SARS-CoV-2 non-structural protein Nsp9: intermediate (ms - μs) dynamics in the C-terminal helix at the dimer interface.Biomol NMR Assign2021
33548324Exploring TERRA during Leishmania major developmental cycle and continuous in vitro passages.Int J Biol Macromol2021
33627513Chromatin-Associated Protein Complexes Link DNA Base J and Transcription Termination in <i>Leishmania</i>.mSphere2021
33760815Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.PLoS One2021
33620038Crystal structure of acetoacetyl-CoA reductase from Rickettsia felis.Acta Crystallogr F Struct Biol Commun2021
34903666Genome instability drives epistatic adaptation in the human pathogen <i>Leishmania</i>.Proc Natl Acad Sci U S A2021
34442725Evolutionary Diversification of Host-Targeted <i>Bartonella</i> Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module.Microorganisms2021
34472979Genome Assemblies across the Diverse Evolutionary Spectrum of <i>Leishmania</i> Protozoan Parasites.Microbiol Resour Announc2021
34592588Arginine sensing in intracellular parasitism of Leishmania.Curr Opin Microbiol2021
34311578Turnover of Variant Surface Glycoprotein in Trypanosoma brucei Is a Bimodal Process.mBio2021
33947893Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1.Sci Rep2021
31237717Structural characterization of β-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites.Proteins2020
31930578Structures of glyceraldehyde 3-phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis.Protein Sci2020
31658388Structural diversity in the Mycobacteria DUF3349 superfamily.Protein Sci2020
31912584Solution structure for an Encephalitozoon cuniculi adrenodoxin-like protein in the oxidized state.Protein Sci2020
31850752Identification of Selective Inhibitors of <i>Plasmodium</i> N-Myristoyltransferase by High-Throughput Screening.J Med Chem2020
33051367Sensing Host Arginine Is Essential for <i>Leishmania</i> Parasites' Intracellular Development.mBio2020
33097187Structural analysis of CACHE domain of the McpA chemoreceptor from Leptospira interrogans.Biochem Biophys Res Commun2020
32576698HGT in the human and skin commensal <i>Malassezia</i>: A bacterially derived flavohemoglobin is required for NO resistance and host interaction.Proc Natl Acad Sci U S A2020
32150903A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466.Mar Drugs2020
32455540Discovery of a Natural Product That Binds to the <i>Mycobacterium tuberculosis</i> Protein Rv1466 Using Native Mass Spectrometry.Molecules2020
30689499Comparative transcriptomics in Leishmania braziliensis: disclosing differential gene expression of coding and putative noncoding RNAs across developmental stages.RNA Biol2019
31358644Dynamic colocalization of 2 simultaneously active <i>VSG</i> expression sites within a single expression-site body in <i>Trypanosoma brucei</i>.Proc Natl Acad Sci U S A2019
31356610Dramatic changes in gene expression in different forms of Crithidia fasciculata reveal potential mechanisms for insect-specific adhesion in kinetoplastid parasites.PLoS Negl Trop Dis2019
31071080Functional genomics in sand fly-derived Leishmania promastigotes.PLoS Negl Trop Dis2019
30894487Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.Proc Natl Acad Sci U S A2019
30980299Quantitative RNA Analysis Using RNA-Seq.Methods Mol Biol2019
31080074Structure-Guided Identification of Resistance Breaking Antimalarial Nâ¿¿Myristoyltransferase Inhibitors.Cell Chem Biol2019
28866109A three-year epidemiological prospective cohort study of rugby league match injuries from the European Super League.J Sci Med Sport2018
30152054Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides.Protein Sci2018
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Collaborators

Kenneth Stuart
Seattle Children's Research Institute
Co-authored papers 74
Wesley C Van Voorhis
Center for Emerging and Re-emerging Infectious Diseases, University of Washington
Co-authored papers 53
Donald D Lorimer
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Co-authored papers 26
Elizabeth A Worthey
Heersink School of Medicine, The University of Alabama at Birmingham
Co-authored papers 15
Alasdair Ivens
University of Washington School of Medicine
Co-authored papers 9
Frederick S Buckner
University of Washington
Co-authored papers 7
Christiane Hertz-Fowler
Institute of Integrative Biology, University of Liverpool
Co-authored papers 6
Matthew Berriman
Wellcome Sanger Institute
Co-authored papers 6
Chang-Yub Kim
Los Alamos National Laboratory
Co-authored papers 4
Thomas C Terwilliger
Los Alamos National Laboratory
Co-authored papers 4
Alka Saxena
Biomedical Research Centre at Guy's Hospital
Co-authored papers 4
Andrew Haydock
Co-authored papers 4
David S Roos
University of Pennsylvania
Co-authored papers 4
Alexis Kaushansky
Seattle Children's Research Institute, University of Washington
Co-authored papers 3
Thomas Earnest
Washington University School of Medicine in St. Louis
Co-authored papers 3
Steven L Salzberg
Center for Computational Biology, Johns Hopkins University
Co-authored papers 3
Peter Tarczy-Hornoch
University of Washington School of Medicine, University of Washington
Co-authored papers 3
Elodie Ghedin
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 3
Christy Vogt
Co-authored papers 3
Owen White
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 3
David Baker
University of Washington
Co-authored papers 3
Christophe L M J Verlinde
University of Washington
Co-authored papers 3
Dhanasekaran Shanmugam
CSIR - National Chemical Laboratory
Co-authored papers 2
Jeremy Peterson
The Institute for Genomic Research, 9712 Medical Center Drive
Co-authored papers 2
Jennifer R Wortman
Broad Institute of MIT and Harvard
Co-authored papers 2
Brian P Brunk
University of Pennsylvania
Co-authored papers 2
Samuel V Angiuoli
Personal Genome Diagnostics Inc.
Co-authored papers 2
Jonathan Crabtree
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 2
David C Schwartz
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Co-authored papers 2
Brian J Haas
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Release 1.2