|
| 35333651 | Structural determinants of dual incretin receptor agonism by tirzepatide. | Proc Natl Acad Sci U S A | 2022 |
| 36171189 | Activation of the human insulin receptor by non-insulin-related peptides. | Nat Commun | 2022 |
| 33721487 | Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor. | J Med Chem | 2021 |
| 32690941 | Structural insights into probe-dependent positive allosterism of the GLP-1 receptor. | Nat Chem Biol | 2020 |
| 30470494 | On the origin of the 2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate scaffold's unique group II selectivity for the mGlu receptors. | Bioorg Med Chem Lett | 2019 |
| 31833461 | Protein Activation in Drug Discovery - Part-II. | Curr Top Med Chem | 2019 |
| 31660833 | Insights into the Structural Aspects of the mGlu Receptor Orthosteric Binding Site. | Curr Top Med Chem | 2019 |
| 31769362 | Protein Activation in Drug Discovery - Part-I. | Curr Top Med Chem | 2019 |
| 31532644 | Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1<i>S</i>,3<i>R</i>)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1<i>H</i>)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Positive Allosteric Modulator of the Human Dopamine D1 Receptor. | J Med Chem | 2019 |
| 29350927 | Synthesis and Pharmacological Characterization of C4<sub>β</sub>-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu<sub>3</sub> Receptor Agonist. | J Med Chem | 2018 |
| 30365309 | Structural Basis for ( S)-3,4-Dicarboxyphenylglycine (DCPG) As a Potent and Subtype Selective Agonist of the mGlu<sub>8</sub> Receptor. | J Med Chem | 2018 |
| 29402739 | Determination of L-AP4-bound human mGlu8 receptor amino terminal domain structure and the molecular basis for L-AP4's group III mGlu receptor functional potency and selectivity. | Bioorg Med Chem Lett | 2018 |
| 28406969 | Reconstruction of 3D structures of MET antibodies from electron microscopy 2D class averages. | PLoS One | 2017 |
| 27749056 | The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470). | J Med Chem | 2016 |
| 26271587 | Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HTâ¿ F receptor agonists: Evolution from bicyclic to monocyclic cores. | Bioorg Med Chem Lett | 2015 |
| 16995730 | Geometric accuracy of three-dimensional molecular overlays. | J Chem Inf Model | 2006 |