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Author Details

Jeff P Bruce
Princess Margaret Cancer Centre, University Health Network
2010
54
29
PMIDPaper TitleJournal TitlePublished Year
36833203Molecular Genetic Characteristics of <i>FANCI</i>, a Proposed New Ovarian Cancer Predisposing Gene.Genes (Basel)2023
37481477Germline whole genome sequencing in adults with multiple primary tumors.Fam Cancer2023
37327320Identifying Mechanisms of Resistance by Circulating Tumor DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at Time of PARP Inhibitor Progression.Clin Cancer Res2023
34556523Mutations in Noncoding <i>Cis</i>-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer.Mol Cancer Res2022
35379580All is not lost: learning from 9p21 loss in cancer.Trends Immunol2022
36875717Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer.Cancer Res Commun2022
36037303A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer.Clin Cancer Res2022
36129469CD8+ Tumor-Infiltrating Lymphocyte Abundance Is a Positive Prognostic Indicator in Nasopharyngeal Cancer.Clin Cancer Res2022
35896551Author Correction: Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.Nat Commun2022
36328595Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing.Life Sci Alliance2022
33417860Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy.Cell2021
33485453Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial.Lancet2021
33633121Elevation in viral entry genes and innate immunity compromise underlying increased infectivity and severity of COVID-19 in cancer patients.Sci Rep2021
34861889A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene.Genome Med2021
34446728Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity.Nat Commun2021
34234122Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.Nat Commun2021
31521748Translational genomics of nasopharyngeal cancer.Semin Cancer Biol2020
32912664Biomarkers of outcome to weekly paclitaxel in epithelial ovarian cancer.Gynecol Oncol2020
32586280MiR-34c downregulation leads to SOX4 overexpression and cisplatin resistance in nasopharyngeal carcinoma.BMC Cancer2020
32444417EVOLVE: A Multicenter Open-Label Single-Arm Clinical and Translational Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer after PARP Inhibition Progression.Clin Cancer Res2020
32345369Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor.Genome Med2020
31303643Safety and tolerability of CFI-400945, a first-in-class, selective PLK4 inhibitor in advanced solid tumours: a phase 1 dose-escalation trial.Br J Cancer2019
31836588Heterogeneous alteration of the ERBB3-MYC axis associated with MEK inhibitor resistance in a <i>KRAS</i>-mutated low-grade serous ovarian cancer patient.Cold Spring Harb Mol Case Stud2019
29590101Bamgineer: Introduction of simulated allele-specific copy number variants into exome and targeted sequence data sets.PLoS Comput Biol2018
30226609hsaâ¿¿miRâ¿¿24 suppresses metastasis in nasopharyngeal carcinoma by regulating the câ¿¿Myc/epithelialâ¿¿mesenchymal transition axis.Oncol Rep2018
30382883Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors.Genome Med2018
30380421Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma.Cell Rep2018
29795279Dysregulation of the MiR-449b target TGFBI alters the TGFβ pathway to induce cisplatin resistance in nasopharyngeal carcinoma.Oncogenesis2018
27827316BRM Promoter Polymorphisms and Survival of Advanced Non-Small Cell Lung Cancer Patients in the Princess Margaret Cohort and CCTG BR.24 Trial.Clin Cancer Res2017
28221868Somatic BRCA1/2 Recovery as a Resistance Mechanism After Exceptional Response to Poly (ADP-ribose) Polymerase Inhibition.J Clin Oncol2017
28419078Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis.Br J Cancer2017
28775249Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas.Nat Commun2017
28006061The KRAS Variant as a Predictive Biomarker of Cetuximab Response in Head and Neck Cancer.JAMA Oncol2017
27010835Human Papillomavirus Genotype Association With Survival in Head and Neck Squamous Cell Carcinoma.JAMA Oncol2016
27723760The genomic landscape of schwannoma.Nat Genet2016
27121877MicroRNAs in nasopharyngeal carcinoma.Chin Clin Oncol2016
27527216HPV Associated Head and Neck Cancer.Cancers (Basel)2016
26983984The complexity of microRNAs in human cancer.J Radiat Res2016
26934316MiR-449a promotes breast cancer progression by targeting CRIP2.Oncotarget2016
25589349Novel insights into head and neck cancer using next-generation "omic" technologies.Cancer Res2015
26351340Nasopharyngeal Cancer: Molecular Landscape.J Clin Oncol2015
25880806Developing a prognostic micro-RNA signature for human cervical carcinoma.PLoS One2015
25970788Prognostic microRNAs modulate the RHO adhesion pathway: A potential therapeutic target in undifferentiated pleomorphic sarcomas.Oncotarget2015
25944123Chromosomal instability as a prognostic marker in cervical cancer.BMC Cancer2015
25738365Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma.Oncotarget2015
25473903The microRNA-218~Survivin axis regulates migration, invasion, and lymph node metastasis in cervical cancer.Oncotarget2015
25367334MicroRNAs in nasopharyngeal carcinoma.Chin J Cancer2014
23505015Tumor-derived exosomes and microvesicles in head and neck cancer: implications for tumor biology and biomarker discovery.Proteomics2013
24145350miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1.Cancer Res2013
23991213Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer.PLoS One2013
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Collaborators

Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 29
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 26
Princess Margaret Cancer Centre
Co-authored papers 12
Research Institute, Princess Margaret Cancer Centre
Co-authored papers 11
Stanford University
Co-authored papers 11
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers 9
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 6
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
University Health Network
Co-authored papers 5
University of Toronto.
Co-authored papers 5
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers 5
University of Toronto, Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Princess Margaret Cancer Centre, University Ave
Co-authored papers 4
Princess Margaret Cancer Centre
Co-authored papers 4
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
University Health Network
Co-authored papers 3
University Health Network
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Princess Margaret Cancer Centre
Co-authored papers 3
College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation
Co-authored papers 3
Princess Margaret Cancer Centre, University Avenue
Co-authored papers 3
Ontario Cancer Institute, University Health Network (UHN)
Co-authored papers 3
Juravinski Cancer Centre
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
National Cancer Institute
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 2
Princess Margaret Cancer Centre, University of Toronto
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2