Author details

Full Name

Yingyao Zhou

Affiliation

Genomics Institute of the Novartis Research Foundation

ORCID

Career Start Year

1997

Papers

H Index

Expertise

CM4AI Collaborator

Trey Ideker (CM4AI)

PMID	Paper Title	Journal Title	Published Year
33967974	Proteomic Analysis of Non-human Primate Peripheral Blood Mononuclear Cells During <i>Burkholderia mallei</i> Infection Reveals a Role of Ezrin in Glanders Pathogenesis.	Front Microbiol	2021
34430930	Predicting drug approvals: The Novartis data science and artificial intelligence challenge.	Patterns (N Y)	2021
32615917	A cell-level quality control workflow for high-throughput image analysis.	BMC Bioinformatics	2020
31929001	Dexamethasone inhibits respiratory syncytial virus-driven mucus production while increasing viral replication without altering antiviral interferon signaling.	Virology	2020
30787302	Identification of a Xist silencing domain by Tiling CRISPR.	Sci Rep	2019
30944313	Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.	Nat Commun	2019
29326268	Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.	Science	2018
29843542	A Fully Automated High-Throughput Flow Cytometry Screening System Enabling Phenotypic Drug Discovery.	SLAS Discov	2018
30523084	Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.	Science	2018
28248290	Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.	Nat Microbiol	2017
26749441	High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.	Cell Host Microbe	2016
27301419	A broad analysis of resistance development in the malaria parasite.	Nat Commun	2016
27313114	An Automatic Quality Control Pipeline for High-Throughput Screening Hit Identification.	J Biomol Screen	2016
26651948	Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.	Cell Host Microbe	2015
24516547	Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns.	PLoS One	2014
22423970	Cofactors required for TLR7- and TLR9-dependent innate immune responses.	Cell Host Microbe	2012
22435989	Chemical and biological properties of frequent screening hits.	J Chem Inf Model	2012
21731658	In silico gene prioritization by integrating multiple data sources.	PLoS One	2011
22096101	Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.	Science	2011
20047295	Chemical-text hybrid search engines.	J Chem Inf Model	2010
20531941	Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-gamma as contributing to enhanced malaria survival.	PLoS One	2010
20386602	A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito.	PLoS Negl Trop Dis	2010
20027183	Human host factors required for influenza virus replication.	Nature	2010
19216790	Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum.	Genome Biol	2009
20020055	Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening.	PLoS One	2009
18405850	Snapshot PK: a rapid rodent in vivo preclinical screening approach.	Drug Discov Today	2008
18854154	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	Cell	2008
18973684	A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum.	BMC Genomics	2008
18454143	Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.	Nat Chem Biol	2008
18579783	In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.	Proc Natl Acad Sci U S A	2008
18257930	In silico discovery of transcription regulatory elements in Plasmodium falciparum.	BMC Genomics	2008
18270564	Evidence-based annotation of the malaria parasite's genome using comparative expression profiling.	PLoS One	2008
18302737	Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells.	Genome Biol	2008
17437647	Study of gene function based on spatial co-expression in a high-resolution mouse brain atlas.	BMC Syst Biol	2007
17939994	A role for IkappaB kinase 2 in bipolar spindle assembly.	Proc Natl Acad Sci U S A	2007
18046333	Distinct physiological states of Plasmodium falciparum in malaria-infected patients.	Nature	2007
17608408	Large-scale annotation of small-molecule libraries using public databases.	J Chem Inf Model	2007
17828270	A probability-based approach for the analysis of large-scale RNAi screens.	Nat Methods	2007
17714805	Exposure of Plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell passage activity.	Mol Biochem Parasitol	2007
17257639	Identification of novel therapeutic targets for HIV infection through functional genomic cDNA screening.	Virology	2007
17255266	An integrated clinical-genomics approach identifies a candidate multi-analyte blood test for serous ovarian carcinoma.	Clin Cancer Res	2007
16537454	A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase.	Proc Natl Acad Sci U S A	2006
24980528	Profiling the kinome for drug discovery.	Drug Discov Today Technol	2006
17092919	Just-in-time purification: an effective solution for cherry-picking and purifying active compounds from large legacy libraries.	J Biomol Screen	2006
17125181	Learning from the data: mining of large high-throughput screening databases.	J Chem Inf Model	2006
16789840	A systematic map of genetic variation in Plasmodium falciparum.	PLoS Pathog	2006
16709248	Haplotype-based quantitative trait mapping using a clustering algorithm.	BMC Bioinformatics	2006
16492761	An efficient rapid system for profiling the cellular activities of molecular libraries.	Proc Natl Acad Sci U S A	2006
15762748	Purifying the masses: integrating prepurification quality control, high-throughput LC/MS purification, and compound plating to feed high-throughput screening.	J Comb Chem	2005
16309285	Novel statistical approach for primary high-throughput screening hit selection.	J Chem Inf Model	2005

1 - 50 of 67

Robert M Flight

University of Kentucky

Career Start Year 2007

Number of shared co-authors 0

Eric Paquet

University of Laval

Career Start Year 2007

Number of shared co-authors 1

Avi Ma'ayan

Icahn School of Medicine at Mount Sinai

Career Start Year 2005

Number of shared co-authors 1

Wenjin Jim Zheng

University of Texas Health Science Center at Houston

Career Start Year 2004

Number of shared co-authors 1

Michael Hsing

University of British Columbia

Career Start Year 2004

Number of shared co-authors 0

Andrey Sivachenko

Cystic Fibrosis Foundation

Career Start Year 2003

Number of shared co-authors 7

Mikhail G Dozmorov

Virginia Commonwealth University

Career Start Year 2001

Number of shared co-authors 1

Gary D Bader

University of Toronto

Career Start Year 2000

Number of shared co-authors 4

Wei Wang

IBM Thomas J Watson Research Center, University of California Los Angeles, University of North Carolina at Chapel Hill

Career Start Year 1999

Number of shared co-authors 1

Tero Aittokallio

Institute for Molecular Medicine Finland (FIMM), University of Helsinki

Career Start Year 1999

Number of shared co-authors 0

Frederick P Roth

University of Toronto

Career Start Year 1998

Number of shared co-authors 2

Thomas Girke

Institute for Integrative Genome Biology, University of California Riverside

Career Start Year 1998

Number of shared co-authors 1

Lars Juhl Jensen

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Career Start Year 1998

Number of shared co-authors 0

Ralf Herwig

Max Planck Institute for Molecular Genetics

Career Start Year 1998

Number of shared co-authors 1

Igor Jurisica

Schroeder Arthritis Institute

Career Start Year 1998

Number of shared co-authors 0

Benno Schwikowski

Center for Bioinformatics, Institut Pasteur CNRS

Career Start Year 1997

Number of shared co-authors 1

Shannon K McWeeney

Oregon Health & Science University, University of California Berkeley

Career Start Year 1997

Number of shared co-authors 3

Vlado Dan????k

Broad Institute

Career Start Year 1997

Number of shared co-authors 5

Christopher T Workman

Technical University of Denmark

Career Start Year 1995

Number of shared co-authors 1

Wolfgang Huber

Technische Universitat Munchen

Career Start Year 1995

Number of shared co-authors 0

Ron Shamir

Tel Aviv University

Career Start Year 1995

Number of shared co-authors 5

Ralf Zimmer

Ludwig-Maximilians-Universitat Munchen

Career Start Year 1995

Number of shared co-authors 2

Ioannis Xenarios

University of Lausanne

Career Start Year 1994

Number of shared co-authors 1

Jason E McDermott

Pacific Northwest National Laboratory

Career Start Year 1993

Number of shared co-authors 0

Zhiping Weng

University of Massachusetts Medical School

Career Start Year 1992

Number of shared co-authors 2

Winston Hide

Harvard Medical School

Career Start Year 1991

Number of shared co-authors 5

John Quackenbush

Harvard T. H. Chan School of Public Health

Career Start Year 1989

Number of shared co-authors 5

Michael F Ochs

The College of New Jersey

Career Start Year 1988

Number of shared co-authors 0

Russ B Altman

Stanford University

Career Start Year 1982

Number of shared co-authors 0

Michael Snyder

Stanford University

Career Start Year 1981

Number of shared co-authors 10

row(s) 1 - 30 of 30

Elizabeth A Winzeler

University of California San Diego

Co-authored papers 28

Karine G Le Roch

Co-authored papers 13

Sumit K Chanda

The Scripps Research Institute

Co-authored papers 10

Dyann F Wirth

The Broad Institute

Co-authored papers 9

Serge Batalov

Co-authored papers 9

Paul D De Jesus

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 8

Jeffrey R Johnson

Gladstone Institutes

Co-authored papers 7

Jeremy S Caldwell

Sirna Therapeutics a former subsidiary of Merck & Co., Inc.

Co-authored papers 7

Kelli Kuhen

Genomics Institute of the Novartis Research Foundation

Co-authored papers 7

Ruben Abagyan

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California

Co-authored papers 6

Renate K??nig

Paul-Ehrlich-Institut

Co-authored papers 5

Chih-Yuan Chiang

United States Army Medical Research Institute of Infectious Diseases

Co-authored papers 5

Case W McNamara

a division of The Scripps Research Institute La Jolla

Co-authored papers 4

Daniel J Carucci

US Military Malaria Vaccine Program, Naval Medical Research Center

Co-authored papers 4

Jianwei Che

Dana-Farber Cancer Institute

Co-authored papers 4

Loren Miraglia

Genomics Institute of the Novartis Research Foundation

Co-authored papers 4

Anthony P Orth

Genomics Institute of the Novartis Research Foundation

Co-authored papers 4

Amanda K Lukens

Harvard T.H. Chan School of Public Health

Co-authored papers 4

Buu Tu

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Co-authored papers 4

Ghislain M C Bonamy

Prestige BioPharma Ltd

Co-authored papers 4

Joseph M Vinetz

Yale University School of Medicine

Co-authored papers 3

Nathanael S Gray

Harvard Medical School

Co-authored papers 3

Lars Pache

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 3

Adolfo Garc??a-Sastre

Icahn School of Medicine at Mount Sinai

Co-authored papers 3

John R Yates

TheScripps Research Institute

Co-authored papers 3

Christopher Benner

Michigan State University College of Human Medicine

Co-authored papers 3

Quy Nguyen

University of California irvine

Co-authored papers 3

Atsushi Inoue

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 2

Silke Stertz

Institute of Medical Virology, University of Zurich

Co-authored papers 2

Markus Warmuth

Co-authored papers 2

1 - 30

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