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Author Details

Shondra M Pruett-Miller
St. Jude Children's Research Hospital.
2006
115
31
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36793425Phenyl Dihydrouracil: An Alternative Cereblon Binder for PROTAC Design.ACS Med Chem Lett2023
37864059Inflammatory cell death, PANoptosis, screen identifies host factors in coronavirus innate immune response as therapeutic targets.Commun Biol2023
37712227Short tandem repeat profiling via next-generation sequencing for cell line authentication.Dis Model Mech2023
37957169A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics.Nat Commun2023
37790524Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia.Res Sq2023
37613636Integrative Microscopy Approaches Reveal Specialized Signaling Filopodia Promote Morphogen Gradient Formation during Mammalian Development.Microsc Microanal2023
37693589The β6 Integrin Negatively Regulates TLR7-Mediated Epithelial Immunity via Autophagy During Influenza A Virus Infection.bioRxiv2023
37986997Biologic and clinical features of childhood gamma delta T-ALL: identification of STAG2/LMO2 γδ T-ALL as an extremely high risk leukemia in the very young.medRxiv2023
37969738The F-box-only protein 44 regulates pregnane X receptor protein level by ubiquitination and degradation.Acta Pharm Sin B2023
37968405Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer.Nature2023
37968277PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors.Nat Commun2023
37425900Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor.bioRxiv2023
37425790Engineering Human Pluripotent Stem Cell Lines to Evade Xenogeneic Transplantation Barriers.bioRxiv2023
37292647Gene editing without <i>ex vivo</i> culture evades genotoxicity in human hematopoietic stem cells.bioRxiv2023
37324531Whole-genome CRISPR screen identifies RAVER1 as a key regulator of RIPK1-mediated inflammatory cell death, PANoptosis.iScience2023
37290501Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection.Mucosal Immunol2023
37289547Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia.Blood Adv2023
37019972Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.Nat Commun2023
37453060Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia.Cell Rep2023
37414763Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma.Nat Commun2023
37205560Phosphorylation of 53BP1 by ATM enforce neurodevelopmental programs in cortical organoids.bioRxiv2023
37400614Potent and uniform fetal hemoglobin induction via base editing.Nat Genet2023
37432749Glutathione limits RUNX2 oxidation and degradation to regulate bone formation.JCI Insight2023
37463047SF3B1 mutation and ATM deletion codrive leukemogenesis via centromeric R-loop dysregulation.J Clin Invest2023
36995667High-Throughput Analysis of CRISPR-Cas9 Editing Outcomes in Cell and Animal Models Using CRIS.py.Methods Mol Biol2023
36882565Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse.Commun Biol2023
36918226CD47 expression is critical for CAR T-cell survival in vivo.J Immunother Cancer2023
36747774Ribonucleotide Reductase Subunit Switching in Hepatoblastoma Drug Response and Relapse.bioRxiv2023
36711662Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia.bioRxiv2023
36798219Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment.medRxiv2023
34767620Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue.Blood2022
35587515ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection.Sci Immunol2022
35406427<i>TERT</i> Expression in Wilms Tumor Is Regulated by Promoter Mutation or Hypermethylation, WT1, and N-MYC.Cancers (Basel)2022
35732731cBAF complex components and MYC cooperate early in CD8<sup>+</sup> T cell fate.Nature2022
35644338FANCL supports Parkin-mediated mitophagy in a ubiquitin ligase-independent manner.Biochim Biophys Acta Mol Basis Dis2022
35671062Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia.Blood Adv2022
35537449NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition.Mol Cell2022
35857643Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma.Sci Transl Med2022
35726022Ca<sup>2+</sup>-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak.Cell Death Differ2022
35820704The MLL3/4 complexes and MiDAC co-regulate H4K20ac to control a specific gene expression program.Life Sci Alliance2022
35513723CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk.Nat Genet2022
35999261A CRISPR/Cas9 engineered Mpl<sup>S504N</sup> mouse model recapitulates human myelofibrosis.Leukemia2022
36095192A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding.Proc Natl Acad Sci U S A2022
36028659Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia.Leukemia2022
35978691SJPYT-195: A Designed Nuclear Receptor Degrader That Functions as a Molecular Glue Degrader of GSPT1.ACS Med Chem Lett2022
36152627Innate frequency-discrimination hyperacuity in Williams-Beuren syndrome mice.Cell2022
35261338SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation.Elife2022
33355188Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin.Cancer Immunol Res2021
33714976Profiling chromatin accessibility in pediatric acute lymphoblastic leukemia identifies subtype-specific chromatin landscapes and gene regulatory networks.Leukemia2021
33570491Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex.Elife2021
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Collaborators

Matthew H Porteus
Stanford University
Co-authored papers 8
Taosheng Chen
St. Jude Children's Research Hospital
Co-authored papers 8
Charles G Mullighan
St Jude Children's Research Hospital
Co-authored papers 7
John Easton
St Jude Children's Research Hospital
Co-authored papers 7
Ching-Hon Pui
St. Jude Children's Research Hospital
Co-authored papers 7
Mitchell J Weiss
Co-authored papers 7
Kristine R Crews
St. Jude Children's Research Hospital
Co-authored papers 5
Chunxu Qu
Co-authored papers 5
William E Evans
Departments of Oncology. St. Jude Children's Research Hospital
Co-authored papers 5
Sima Jeha
St. Jude Children's Research Hospital
Co-authored papers 5
Mary V Relling
Departments of Pharmaceutical Sciences.
Co-authored papers 5
Jinghui Zhang
Changhai Hospital, Second Military Medical University
Co-authored papers 5
Kathryn G Roberts
St Jude Children's Research Hospital
Co-authored papers 4
Xiang Chen
St. Jude Children's Research Hospital
Co-authored papers 4
Xiaotu Ma
St. Jude Children's Research Hospital
Co-authored papers 4
J Keith Joung
Massachusetts General Hospital
Co-authored papers 4
Yanling Liu
St. Jude Children's Research Hospital
Co-authored papers 3
Morgan L Maeder
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 3
Jeffery M Klco
St. Jude Children's Research Hospital
Co-authored papers 3
Malia B Potts
St. Jude Children's Research Hospital
Co-authored papers 3
Scot A Wolfe
Co-authored papers 3
Phuong Nguyen
Hoag Memorial Hospital Presbyterian
Co-authored papers 3
Mignon L Loh
University of Washington
Co-authored papers 2
Stacey Thibodeau-Beganny
Amherst College
Co-authored papers 2
Anang A Shelat
St. Jude Children's Research Hospital
Co-authored papers 2
Kim E Nichols
St. Jude Children's Research Hospital
Co-authored papers 2
David R Liu
Co-authored papers 2
Gregory A Newby
Co-authored papers 2
Geoffrey Neale
St. Jude Children's Research Hospital
Co-authored papers 2
Charles W M Roberts
Co-authored papers 2
Release 1.2