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Author Details

Thomas J Kipps
University of California San Diego
1977
479
117
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36672456Characteristics and Clinical Outcomes of Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Receiving Ibrutinib for â¿¥5 Years in the RESONATE-2 Study.Cancers (Basel)2023
37871223Expression signature of human endogenous retroviruses in chronic lymphocytic leukemia.Proc Natl Acad Sci U S A2023
37315225Immune restoration with ibrutinib plus venetoclax in first-line chronic lymphocytic leukemia: the phase 2 CAPTIVATE study.Blood Adv2023
37282671Outcomes in Patients with High-Risk Features after Fixed-Duration Ibrutinib plus Venetoclax: Phase II CAPTIVATE Study in First-Line Chronic Lymphocytic Leukemia.Clin Cancer Res2023
36944183Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway.Oncotarget2023
37279436Challenging the Value of Minimal Residual Disease in Predicting Outcome of Patients With Chronic Lymphocytic Leukemia.J Clin Oncol2023
37029329Association of baseline ROR1 and ROR2 gene expression with clinical outcomes in the I-SPY2 neoadjuvant breast cancer trial.Breast Cancer Res Treat2023
36624313Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome.Nat Med2023
36617990Many People With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Benefit From Ibrutinib Treatment Up To 8 Years: A Plain Language Summary.Future Oncol2023
34285341Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans.Leukemia2022
35406490Recent Advances in CAR T-Cell Therapy for Patients with Chronic Lymphocytic Leukemia.Cancers (Basel)2022
35580162ROR1: an orphan becomes apparent.Blood2022
35377947Up to 8-year follow-up from RESONATE-2: first-line ibrutinib treatment for patients with chronic lymphocytic leukemia.Blood Adv2022
35605176Enduring undetectable MRD and updated outcomes in relapsed/refractory CLL after fixed-duration venetoclax-rituximab.Blood2022
35361793cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies.Nat Commun2022
35418613High expression level of ROR1 and ROR1-signaling associates with venetoclax resistance in chronic lymphocytic leukemia.Leukemia2022
35714675NCCN Guidelines® Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 3.2022.J Natl Compr Canc Netw2022
35747847B-cell Receptor Signaling Induced Metabolic Alterations in Chronic Lymphocytic Leukemia Can Be Partially Bypassed by <i>TP53</i> Abnormalities.Hemasphere2022
36551520Obinutuzumab, High-Dose Methylprednisolone (HDMP), and Lenalidomide for the Treatment of Patients with Richter's Syndrome.Cancers (Basel)2022
35903706Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia.Front Oncol2022
35927489Molecular map of chronic lymphocytic leukemia and its impact on outcome.Nat Genet2022
35983732Utility of measurable residual disease for predicting treatment outcomes with BCR- and BCL2-Targeted therapies in patients with CLL.Leuk Lymphoma2022
35014928Up to 6.5 years (median 4 years) of follow-up of first-line ibrutinib in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma and high-risk genomic features: integrated analysis of two phase 3 studies.Leuk Lymphoma2022
35064090A large fraction of trisomy 12, 17p<sup>-</sup>, and 11q<sup>-</sup> CLL cases carry unidentified microdeletions of <i>miR-15a/16-1</i>.Proc Natl Acad Sci U S A2022
35196370Fixed-duration ibrutinib plus venetoclax for first-line treatment of CLL: primary analysis of the CAPTIVATE FD cohort.Blood2022
35230971Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B.Aging (Albany NY)2022
35020831Single-cell analysis reveals immune dysfunction from the earliest stages of CLL that can be reversed by ibrutinib.Blood2022
35103064Ibrutinib plus Obinutuzumab as Frontline Therapy for Chronic Lymphocytic Leukemia Is Associated with a Lower Rate of Infusion-Related Reactions and with Sustained Remissions after Ibrutinib Discontinuation: A Single-Arm, Open-Label, Phase 1b/2 Clinical Trial NCT0231576.Adv Hematol2022
34699592Phase 1 TRANSCEND CLL 004 study of lisocabtagene maraleucel in patients with relapsed/refractory CLL or SLL.Blood2022
33097837Wnt5a enhances proliferation of chronic lymphocytic leukemia and ERK1/2 phosphorylation via a ROR1/DOCK2-dependent mechanism.Leukemia2021
33730844Phase II study of acalabrutinib in ibrutinib-intolerant patients with relapsed/refractory chronic lymphocytic leukemia.Haematologica2021
33611131Impact of long-term ibrutinib treatment on circulating immune cells in previously untreated chronic lymphocytic leukemia.Leuk Res2021
33689703A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation.Cancer Cell2021
33604581Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy.Blood Cancer Discov2021
34939038Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment.Nat Cancer2021
34618601Ibrutinib Plus Venetoclax for First-Line Treatment of Chronic Lymphocytic Leukemia: Primary Analysis Results From the Minimal Residual Disease Cohort of the Randomized Phase II CAPTIVATE Study.J Clin Oncol2021
34398557Mining the Microenvironment for Therapeutic Targets in Chronic Lymphocytic Leukemia.Cancer J2021
34686499Activation of <i>Notch</i> and <i>Myc</i> Signaling via B-cell-Restricted Depletion of <i>Dnmt3a</i> Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.Cancer Res2021
34075408Exploring the pathways to chronic lymphocytic leukemia.Blood2021
34115103Efficacy of venetoclax plus rituximab for relapsed CLL: 5-year follow-up of continuous or limited- duration therapy.Blood2021
34112698Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History.Cancer Discov2021
34083230Long-term Follow-up of Patients with Relapsed or Refractory Non-Hodgkin Lymphoma Treated with Venetoclax in a Phase I, First-in-Human Study.Clin Cancer Res2021
33171493miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors.Blood2021
33451349Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.J Hematol Oncol2021
31048356Ibrutinib reduces obinutuzumab infusion-related reactions in patients with chronic lymphocytic leukemia and is associated with changes in plasma cytokine levels.Haematologica2020
31996785Aurora B induces epithelial-mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis.Oncogene2020
31992855NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia.Cell Death Differ2020
32023533Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology.J Natl Compr Canc Netw2020
32888452Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3 trial.Lancet Oncol2020
32938797Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.Sci Transl Med2020
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Collaborators

University of California San Diego
Co-authored papers 170
Co-authored papers 32
Co-authored papers 16
Herbert Wertheim School of Public Health, University of California San Diego
Co-authored papers 9
Stanford Cancer Institute, Stanford University
Co-authored papers 9
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 8
Co-authored papers 6
German Cancer Research Center
Co-authored papers 6
University of California, USA Institute for Genomic Medicine
Co-authored papers 6
Co-authored papers 6
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Broad Institute of Massachusetts Institute of Technology and Harvard
Co-authored papers 5
The Ohio State University Comprehensive Cancer Center
Co-authored papers 4
Departments of Bioinformatics and Clinical Genomics, Illumina Inc.
Co-authored papers 4
Co-authored papers 4
Medical College of Georgia
Co-authored papers 4
University of California San Diego
Co-authored papers 4
Institute for Genomic Medicine, University of California San Diego
Co-authored papers 4
Co-authored papers 4
Department of Pediatrics and Rady's Children's Hospital, University of California
Co-authored papers 4
University of California san francisco
Co-authored papers 4
Broad Institute of MIT and Harvard
Co-authored papers 3
Co-authored papers 3
Taussig Cancer Institute, Cleveland Clinic
Co-authored papers 3
Oncology R&D
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Stanford University
Co-authored papers 3
Sapienza University.
Co-authored papers 3
Co-authored papers 3