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Author Details

Darren Ennis
Ovarian Cancer Action Research Centre, Imperial College London
2004
35
21
PMIDPaper TitleJournal TitlePublished Year
36928279Efficacy and Safety of Weekly Paclitaxel Plus Vistusertib vs Paclitaxel Alone in Patients With Platinum-Resistant Ovarian High-Grade Serous Carcinoma: The OCTOPUS Multicenter, Phase 2, Randomized Clinical Trial.JAMA Oncol2023
37752102Author Correction: The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma.Nat Commun2023
37845213Molecular landscape and functional characterization of centrosome amplification in ovarian cancer.Nat Commun2023
37474499The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma.Nat Commun2023
35131874Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous Carcinoma.Mol Cancer Ther2022
35398881The Genomic Landscape of Early-Stage Ovarian High-Grade Serous Carcinoma.Clin Cancer Res2022
33570999FrenchFISH: Poisson Models for Quantifying DNA Copy Number From Fluorescence In Situ Hybridization of Tissue Sections.JCO Clin Cancer Inform2021
32195317NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer.Mol Ther Oncolytics2020
32554541Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).Clin Cancer Res2020
32473302Prognostic gene expression signature for high-grade serous ovarian cancer.Ann Oncol2020
30835824Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference.Cancer2019
30464341Mannose impairs tumour growth and enhances chemotherapy.Nature2018
30104763Copy number signatures and mutational processes in ovarian carcinoma.Nat Genet2018
29238045RIPK3 promotes adenovirus type 5 activity.Cell Death Dis2017
28198360Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.Nat Commun2017
28359078Safety and utility of image-guided research biopsies in relapsed high-grade serous ovarian carcinoma-experience of the BriTROC consortium.Br J Cancer2017
28954785The Driver Mutational Landscape of Ovarian Squamous Cell Carcinomas Arising in Mature Cystic Teratoma.Clin Cancer Res2017
26948875The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis.Curr Biol2016
27306793Neoadjuvant Chemotherapy Modulates the Immune Microenvironment in Metastases of Tubo-Ovarian High-Grade Serous Carcinoma.Clin Cancer Res2016
27530326CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma.Cancer Res2016
26681675Methanol-based fixation is superior to buffered formalin for next-generation sequencing of DNA from clinical cancer samples.Ann Oncol2016
25560085Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control.Mol Oncol2015
26807325Noninvasive urinary miRNA biomarkers for early detection of pancreatic adenocarcinoma.Am J Cancer Res2015
26124480Chemotherapy Response Score: Development and Validation of a System to Quantify Histopathologic Response to Neoadjuvant Chemotherapy in Tubo-Ovarian High-Grade Serous Carcinoma.J Clin Oncol2015
26240291Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma.Clin Cancer Res2015
23825230Endothelial cell junctional adhesion molecule C plays a key role in the development of tumors in a murine model of ovarian cancer.FASEB J2013
22322968The peritoneal tumour microenvironment of high-grade serous ovarian cancer.J Pathol2012
22219323Production of TNF-α in macrophages activated by T cells, compared with lipopolysaccharide, uses distinct IL-10-dependent regulatory mechanism.J Immunol2012
19306979Differential molecular changes in patients with asymptomatic long-segment Barrett's esophagus treated by antireflux surgery or medical therapy.Am J Surg2010
20632267Associations between leptin and adiponectin receptor upregulation, visceral obesity and tumour stage in oesophageal and junctional adenocarcinoma.Br J Surg2010
20189371Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast cancer.Clin Oncol (R Coll Radiol)2010
19392848Building a bioresource for esophageal research: lessons from the early experience of an academic medical center.Dis Esophagus2010
15753254Acellular pertussis vaccine protects against exacerbation of allergic asthma due to Bordetella pertussis in a murine model.Clin Diagn Lab Immunol2005
15626480Whole-cell pertussis vaccine protects against Bordetella pertussis exacerbation of allergic asthma.Immunol Lett2005
15347385Prior Bordetella pertussis infection modulates allergen priming and the severity of airway pathology in a murine model of allergic asthma.Clin Exp Allergy2004
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Collaborators

Ovarian Cancer Action Research Centre, Imperial College London
Co-authored papers 23
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 12
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 10
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 9
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 8
CRUK Clinical Trials Unit, University of Glasgow
Co-authored papers 7
University of Glasgow
Co-authored papers 6
Barts Health NHS Trust
Co-authored papers 6
University of Cambridge
Co-authored papers 6
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 5
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 4
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 4
University of British Columbia
Co-authored papers 3
Peter MacCallum Cancer Centre
Co-authored papers 3
The Royal Marsden NHS Foundation Trust and Institute of Cancer Research
Co-authored papers 3
University of British Columbia
Co-authored papers 3
Peter MacCallum Cancer Centre
Co-authored papers 2
Fred Hutchinson Cancer Research Center
Co-authored papers 2
Hollings Cancer Center, Medical University of South Carolina
Co-authored papers 2
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 2
University of Alberta, Canada Cross Cancer Institute
Co-authored papers 2
Peter MacCallum Cancer Centre
Co-authored papers 2
Instituto de Salud Carlos III
Co-authored papers 2
Rollins School of Public Health, Emory University
Co-authored papers 2
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 2
Institute of Clinical Trials and Methodology, University College London
Co-authored papers 2
John A. Burns School of Medicine, University of Hawaii
Co-authored papers 2
University of Cambridge
Co-authored papers 2
Ovarian Cancer Action Research Centre, Imperial College London
Co-authored papers 2
International Hereditary Cancer Center, Pomeranian Medical University
Co-authored papers 2