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Author Details

Hui Zheng
Baylor College of Medicine
1989
128
65
PMIDPaper TitleJournal TitlePublished Year
36798205TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy.bioRxiv2023
37580742Oleoylethanolamide facilitates PPARα and TFEB signaling and attenuates Aβ pathology in a mouse model of Alzheimer's disease.Mol Neurodegener2023
37317973Complement C3aR depletion reverses HIF-1α-induced metabolic impairment and enhances microglial response to Aβ pathology.J Clin Invest2023
36646931Droplet-based transcriptome profiling of individual synapses.Nat Biotechnol2023
36711875Oleoylethanolamide facilitates PPARa and TFEB signaling and attenuates Ab pathology in a mouse model of Alzheimer's disease.Res Sq2023
36070367A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease.Sci Transl Med2022
35443157Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques.Immunity2022
32366951TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading.Mol Psychiatry2021
33517893Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer's disease neuropathology.Mol Neurodegener2021
34727995Role of FoxO transcription factors in aging and age-related metabolic and neurodegenerative diseases.Cell Biosci2021
34187889Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading.Proc Natl Acad Sci U S A2021
34247441FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology.Aging Cell2021
33234021Complement in Neurologic Disease.Annu Rev Pathol2021
32990682Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging.J Clin Invest2021
32426924Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community.Alzheimers Dement2020
31931428Plasma levels of Interleukin 18 but not amyloid-β or Tau are elevated in female depressive patients.Compr Psychiatry2020
31917687Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease.J Clin Invest2020
33298560An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease.Sci Transl Med2020
32668255Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.Cell Rep2020
30610193Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits.Nat Commun2019
30290707The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau).Autophagy2019
29604409Hippocampal gene expression profiling in a rat model of functional constipation reveals abnormal expression genes associated with cognitive function.Neurosci Lett2018
29997299Concurrent cell type-specific isolation and profiling of mouse brains in inflammation and Alzheimer's disease.JCI Insight2018
30008664Compensatory Mechanisms Modulate the Neuronal Excitability in a Kainic Acid-Induced Epilepsy Mouse Model.Front Neural Circuits2018
30108137TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading.J Exp Med2018
30603085Amyloid, tau, pathogen infection and antimicrobial protection in Alzheimer's disease -conformist, nonconformist, and realistic prospects for AD pathogenesis.Transl Neurodegener2018
30285785Peripheral immune system in aging and Alzheimer's disease.Mol Neurodegener2018
30415998Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease.Neuron2018
30355319Correction to: Peripheral immune system in aging and Alzheimer's disease.Mol Neurodegener2018
28054918APP modulates KCC2 expression and function in hippocampal GABAergic inhibition.Elife2017
29273078Practical considerations for choosing a mouse model of Alzheimer's disease.Mol Neurodegener2017
28785723The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance.eNeuro2017
28842416Synaptic Adhesion Molecule Pcdh-γC5 Mediates Synaptic Dysfunction in Alzheimer's Disease.J Neurosci2017
26968346The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective.Trends Neurosci2016
29104891Microglial Phagocytosis Assay.Bio Protoc2016
29104890Protocol for Primary Microglial Culture Preparation.Bio Protoc2016
26546579Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease.J Neurochem2016
27207529Neuronal Deletion of Ghrelin Receptor Almost Completely Prevents Diet-Induced Obesity.Diabetes2016
26941642Implications of GABAergic Neurotransmission in Alzheimer's Disease.Front Aging Neurosci2016
26758846Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease.J Neurosci2016
27112488A seeding based cellular assay of tauopathy.Mol Neurodegener2016
24614496Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease.Mol Psychiatry2015
25673853Posttraumatic stress disorder-like induction elevates β-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses.J Neurosci2015
25533482NFκB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease.Neuron2015
24623762Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease.J Neurosci2014
25274811The amyloid precursor protein controls adult hippocampal neurogenesis through GABAergic interneurons.J Neurosci2014
25069841Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB.EMBO Mol Med2014
25108425Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow.Mol Neurodegener2014
24278307Modeling Alzheimer's disease in mouse without mutant protein overexpression: cooperative and independent effects of Aβ and tau.PLoS One2013
21605029Role of APP and Aβ in synaptic physiology.Curr Alzheimer Res2012
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Collaborators

Co-authored papers 9
Baylor College of Medicine
Co-authored papers 6
Baylor College of Medicine
Co-authored papers 4
Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital
Co-authored papers 4
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 4
The Wellcome Trust Sanger Institute
Co-authored papers 4
Emory Center for Neurodegenerative Disease
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
University of Pennsylvania
Co-authored papers 2
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
Co-authored papers 2
Institute for Cell Engineering, Johns Hopkins University School of Medicine
Co-authored papers 1
Microsoft Corporation
Co-authored papers 1
Co-authored papers 1
The Scripps Research Institute, University of California
Co-authored papers 1
German Center for Neurodegenerative Diseases (DZNE) Munich
Co-authored papers 1
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 1
Institute for Systems Biology
Co-authored papers 1
Benaroya Research Institute at Virginia Mason
Co-authored papers 1
Emory University School of Medicine
Co-authored papers 1
Institute for Systems Biology
Co-authored papers 1
Rush University Medical Center
Co-authored papers 1
Institute of Medical Sciences, Banaras Hindu University
Co-authored papers 1
Mayo Clinic Rochester
Co-authored papers 1
University of British Columbia and BC Children's Hospital
Co-authored papers 1
Stem Cell Translational Research Center of Tongji Hospital, Tongji University
Co-authored papers 1
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Mayo Clinic
Co-authored papers 1
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