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Author Details

Adrian C Begg
The Netherlands Cancer Institute
1945
180
47
PMIDPaper TitleJournal TitlePublished Year
26265694Pretreatment microRNA Expression Impacting on Epithelial-to-Mesenchymal Transition Predicts Intrinsic Radiosensitivity in Head and Neck Cancer Cell Lines and Patients.Clin Cancer Res2015
22852555Investigation of possible endogenous hypoxia markers in colorectal cancer.Int J Radiat Biol2013
23849170The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia.Radiother Oncol2013
23165123Predicting outcomes in radiation oncology--multifactorial decision support systems.Nat Rev Clin Oncol2013
22385918Predicting recurrence after radiotherapy in head and neck cancer.Semin Radiat Oncol2012
21430696Strategies to improve radiotherapy with targeted drugs.Nat Rev Cancer2011
219444625-aminoimidazole-4-carboxamide riboside enhances effect of ionizing radiation in PC3 prostate cancer cells.Int J Radiat Oncol Biol Phys2011
20070218Radiobiology: state of the present art. A conference report.Int J Radiat Biol2010
21301045POLQ in breast cancer.Oncotarget2010
20837694CD44 expression predicts local recurrence after radiotherapy in larynx cancer.Clin Cancer Res2010
20832016Targeting base excision repair as a sensitization strategy in radiotherapy.Semin Radiat Oncol2010
20978197Targeted radiosensitization of cells expressing truncated DNA polymerase {beta}.Cancer Res2010
20346528HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors.Radiother Oncol2010
20338472Establishment of a Radiogenomics Consortium.Int J Radiat Oncol Biol Phys2010
19059500Mechanism of cell killing after ionizing radiation by a dominant negative DNA polymerase beta.DNA Repair (Amst)2009
19863199Predicting response to radiotherapy: evolutions and revolutions.Int J Radiat Biol2009
19735873A gene expression model of intrinsic tumor radiosensitivity: prediction of response and prognosis after chemoradiation.Int J Radiat Oncol Biol Phys2009
19160427Radiotherapy in laryngeal carcinoma: can a panel of 13 markers predict response?Laryngoscope2009
19253368Molecular markers predict outcome in squamous cell carcinoma of the head and neck after concomitant cisplatin-based chemoradiation.Int J Cancer2009
17639394Cisplatin-DNA adduct formation in patients treated with cisplatin-based chemoradiation: lack of correlation between normal tissues and primary tumor.Cancer Chemother Pharmacol2008
18314061Prognostic and predictive markers in oncology. Introduction.Semin Radiat Oncol2008
18313778Clinical radiobiology in 2008.Radiother Oncol2008
18237797Cell cycle phase dependent role of DNA polymerase beta in DNA repair and survival after ionizing radiation.Radiother Oncol2008
18037478Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer.Gynecol Oncol2008
17126614Role for DNA polymerase beta in response to ionizing radiation.DNA Repair (Amst)2007
17931799Gene expression profiling to predict outcome after chemoradiation in head and neck cancer.Int J Radiat Oncol Biol Phys2007
18088185Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells.Radiat Res2007
17532074Impact of supervised gene signatures of early hypoxia on patient survival.Radiother Oncol2007
17615564Heterogeneity of gene expression profiles in head and neck cancer.Head Neck2007
17705630Involvement of DNA polymerase beta in repair of ionizing radiation damage as measured by in vitro plasmid assays.Radiat Res2007
16343804Resistance of hypoxic cells to ionizing radiation is influenced by homologous recombination status.Int J Radiat Oncol Biol Phys2006
17076565Can the severity of normal tissue damage after radiation therapy be predicted?PLoS Med2006
16916559Microsatellite alterations in head and neck squamous cell carcinoma and relation to expression of pimonidazole, CA IX and GLUT-1.Radiother Oncol2006
16533789Radiosensitization of squamous cell carcinoma by the alkylphospholipid perifosine in cell culture and xenografts.Clin Cancer Res2006
16550603Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT).Int J Cancer2006
16618579Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers.Int J Radiat Oncol Biol Phys2006
16024118Radiosensitization by a dominant negative to DNA polymerase beta is DNA polymerase beta-independent and XRCC1-dependent.Radiother Oncol2005
15952198Hypoxia in head and neck cancer: how much, how important?Head Neck2005
15913908Hypoxic cell turnover in different solid tumor lines.Int J Radiat Oncol Biol Phys2005
16029781Molecular markers predicting radiotherapy response: report and recommendations from an International Atomic Energy Agency technical meeting.Int J Radiat Oncol Biol Phys2005
15990022Thymidine analogues to assess microperfusion in human tumors.Int J Radiat Oncol Biol Phys2005
15036858Differentiation-associated staining with anti-pimonidazole antibodies in head and neck tumors.Radiother Oncol2004
12829124Is HIF-1alpha a good marker for tumor hypoxia?Int J Radiat Oncol Biol Phys2003
14643948Towards genetic prediction of radiation responses: ESTRO's GENEPI project.Radiother Oncol2003
11870530Accelerated hyperfractionation (AHF) compared to conventional fractionation (CF) in the postoperative radiotherapy of locally advanced head and neck cancer: influence of proliferation.Br J Cancer2002
12242121Editorial radiotherapy and oncology 2002: predictive assays for normal tissue damage.Radiother Oncol2002
12192567Phase 1 study to identify tumour hypoxia in patients with head and neck cancer using technetium-99m BRU 59-21.Eur J Nucl Med Mol Imaging2002
12175565Premature chromosome condensation and cell separation studies in biopsies from head and neck tumors for radiosensitivity prediction.Radiother Oncol2002
12459383HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors.Int J Radiat Oncol Biol Phys2002
12005553Rapid fluorescence ratio assay for detecting changes in radiosensitivity.Radiat Res2002
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Collaborators

Frank J P Hoebers
Maastricht University Medical Centre
Co-authored papers 9
Coen R N Rasch
Leiden University Medical Center
Co-authored papers 6
Jan H M Schellens
Department of Pharmaceutical Sciences, Utrecht University
Co-authored papers 3
Lodewyk F A Wessels
University Medical Centre Mannheim, University of Heidelberg
Co-authored papers 3
Philippe Lambin
Maastricht University
Co-authored papers 3
Albert J van der Kogel
University of Wisconsin School of Medicine and Public Health
Co-authored papers 3
Johan Bussink
Radboud University, Nijmegen Medical Centre
Co-authored papers 3
Maud H W Starmans
Ontario Institute for Cancer Research
Co-authored papers 3
Catharine M L West
University of Manchester
Co-authored papers 2
Laurence Collette
Belgium International Drug Development Institute
Co-authored papers 2
Bradly G Wouters
Princess Margaret Cancer Centre, University Health Network and, University of Toronto
Co-authored papers 2
Johannes H A M Kaanders
Radboud University Medical Center
Co-authored papers 2
Michel Bolla
universite Grenoble-Alpes (UGA)
Co-authored papers 2
Laura J Van't Veer
University of California San Francisco
Co-authored papers 2
Dirk De Ruysscher
Maastro Clinic
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Marc Vooijs
Maastricht University Medical Centre+
Co-authored papers 1
Hendrik Van Poppel
University Hospitals Leuven
Co-authored papers 1
Robert G Bristow
University of Toronto
Co-authored papers 1
Emmanuel Rios Velazquez
Research Institute GROW, Maastricht University
Co-authored papers 1
Andre Dekker
Maastricht University Medical Centre
Co-authored papers 1
Vincenzo Valentini
Universita Cattolica del Sacro Cuore
Co-authored papers 1
Lukas J A Stalpers
Co-authored papers 1
Micha??l G Magagnin
GROW Research Institute, Maastricht University
Co-authored papers 1
Pierluigi Granone
Catholic University
Co-authored papers 1
Kathleen M Darcy
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
Co-authored papers 1
Erik Roelofs
Maastricht University Medical Centre+
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Renaud Seigneuric
INSERM
Co-authored papers 1
Wouter van Elmpt
Maastricht University Medical Center+
Co-authored papers 1
Ruud G P M van Stiphout
University of Oxford
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Release 1.2