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Author Details
Full Name
Mark A Gregory
Affiliation
University of Colorado Anschutz Medical Campus
ORCID
Career Start Year
2000
Papers
18
H Index
15
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36259537
Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation.
Elife
2022
30940653
Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.
Clin Cancer Res
2019
28947392
Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia.
Exp Hematol
2018
27791036
ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.
Proc Natl Acad Sci U S A
2016
25547679
Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations.
Clin Cancer Res
2015
24891015
Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1(+) leukemia.
Am J Hematol
2014
22941562
Using functional genomics to overcome therapeutic resistance in hematological malignancies.
Immunol Res
2013
23757356
Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.
Clin Cancer Res
2013
23277542
Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity.
Proc Natl Acad Sci U S A
2013
23056582
Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer.
PLoS One
2012
20609354
Wnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl.
Cancer Cell
2010
15655352
The ARF tumor suppressor: keeping Myc on a leash.
Cell Cycle
2005
15361884
p19ARF directly and differentially controls the functions of c-Myc independently of p53.
Nature
2004
15241487
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol.
Oncogene
2004
14563837
Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization.
J Biol Chem
2003
10713166
c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells.
Mol Cell Biol
2000
11039906
B-Myc is preferentially expressed in hormonally-controlled tissues and inhibits cellular proliferation.
Oncogene
2000
10866684
Disruption of Myc-tubulin interaction by hyperphosphorylation of c-Myc during mitosis or by constitutive hyperphosphorylation of mutant c-Myc in Burkitt's lymphoma.
Mol Cell Biol
2000
1 - 18 of 18
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row(s) 1 - 30 of 30
Collaborators
James DeGregori
University of Colorado Anschutz Medical Campus
Co-authored papers
9
Vadym Zaberezhnyy
University of Colorado Anschutz Medical Campus
Co-authored papers
6
Veronica Clavijo Jordan
Harvard Medical School
Co-authored papers
4
Daniel A Pollyea
University of Colorado Division of Hematology
Co-authored papers
3
Angelo D'Alessandro
University of Colorado Anschutz Medical Campus
Co-authored papers
3
Travis Nemkov
University of Colorado Anschutz Medical Campus
Co-authored papers
3
Kirk C Hansen
University of Colorado Anschutz Medical Campus
Co-authored papers
3
Biniam Adane
The Broad Institute of MIT and Harvard
Co-authored papers
2
Aik Choon Tan
Huntsman Cancer Institute, The University of Utah
Co-authored papers
2
Brian J Druker
Oregon Health & Science University
Co-authored papers
1
Christopher C Porter
Emory University School of Medicine
Co-authored papers
1
Andrii I Rozhok
University of Colorado Anschutz Medical Campus
Co-authored papers
1
Sarah Gehrke
University of Colorado Anschutz Medical Campus
Co-authored papers
1
Catherine Pham-Danis
University of Colorado Anschutz Medical Campus
Co-authored papers
1
Julie A Reisz
University of Colorado Anschutz Medical Campus
Co-authored papers
1
Thomas O'Hare
Huntsman Cancer Institute, University of Utah
Co-authored papers
1
Christopher A Eide
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers
1
Brett M Stevens
University of Colorado School of Medicine
Co-authored papers
1
Hae-Joon Park
University of Colorado Anschutz Medical Campus
Co-authored papers
1
Andrew Goodspeed
University of Colorado Denver | Anschutz Medical Campus
Co-authored papers
1
Wells A Messersmith
University of Colorado Anschutz Medical Campus
Co-authored papers
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