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Author Details

Mark A Gregory
University of Colorado Anschutz Medical Campus
2000
18
15
PMIDPaper TitleJournal TitlePublished Year
36259537Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation.Elife2022
30940653Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.Clin Cancer Res2019
28947392Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia.Exp Hematol2018
27791036ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.Proc Natl Acad Sci U S A2016
25547679Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations.Clin Cancer Res2015
24891015Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1(+) leukemia.Am J Hematol2014
22941562Using functional genomics to overcome therapeutic resistance in hematological malignancies.Immunol Res2013
23757356Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.Clin Cancer Res2013
23277542Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity.Proc Natl Acad Sci U S A2013
23056582Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer.PLoS One2012
20609354Wnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl.Cancer Cell2010
15655352The ARF tumor suppressor: keeping Myc on a leash.Cell Cycle2005
15361884p19ARF directly and differentially controls the functions of c-Myc independently of p53.Nature2004
15241487MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol.Oncogene2004
14563837Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization.J Biol Chem2003
10713166c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells.Mol Cell Biol2000
11039906B-Myc is preferentially expressed in hormonally-controlled tissues and inhibits cellular proliferation.Oncogene2000
10866684Disruption of Myc-tubulin interaction by hyperphosphorylation of c-Myc during mitosis or by constitutive hyperphosphorylation of mutant c-Myc in Burkitt's lymphoma.Mol Cell Biol2000
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Collaborators

University of Colorado Anschutz Medical Campus
Co-authored papers 9
University of Colorado Anschutz Medical Campus
Co-authored papers 6
Harvard Medical School
Co-authored papers 4
University of Colorado Division of Hematology
Co-authored papers 3
University of Colorado Anschutz Medical Campus
Co-authored papers 3
University of Colorado Anschutz Medical Campus
Co-authored papers 3
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Co-authored papers 3
The Broad Institute of MIT and Harvard
Co-authored papers 2
Huntsman Cancer Institute, The University of Utah
Co-authored papers 2
Oregon Health & Science University
Co-authored papers 1
Emory University School of Medicine
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Huntsman Cancer Institute, University of Utah
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
University of Colorado School of Medicine
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
University of Colorado Denver | Anschutz Medical Campus
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1