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Author Details

Georg Kochs
Institute of Virology, Freiburg University Medical Center, University of Freiburg
1978
159
62
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36155255Transmission characteristics, replication patterns and clinical manifestations of human monkeypox virus-an in-depth analysis of four cases from Germany.Clin Microbiol Infect2023
37720217Interleukin-36γ is causative for liver damage upon infection with Rift Valley fever virus in type I interferon receptor-deficient mice.Front Immunol2023
37582777mRNA 3'UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus.Nat Commun2023
37643129Bourbon virus, a newly discovered zoonotic thogotovirus.J Gen Virol2023
37037847Total escape of SARS-CoV-2 from dual monoclonal antibody therapy in an immunocompromised patient.Nat Commun2023
36749070The Antiviral Activity of Equine Mx1 against Thogoto Virus Is Determined by the Molecular Structure of Its Viral Specificity Region.J Virol2023
36758070Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication.Science2023
35019718Comparative Study of Ten Thogotovirus Isolates and Their Distinct <i>In Vivo</i> Characteristics.J Virol2022
35475759The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses.Elife2022
35779780Passive immunization against COVID-19 by anti-SARS-CoV-2 spike IgG in commercially available immunoglobulin preparations in severe antibody deficiency.J Allergy Clin Immunol Pract2022
35484232SARS-CoV-2-specific T-cell epitope repertoire in convalescent and mRNA-vaccinated individuals.Nat Microbiol2022
35941157COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation.Nat Commun2022
36129445Impaired immune response drives age-dependent severity of COVID-19.J Exp Med2022
35879345Optimized intramuscular immunization with VSV-vectored spike protein triggers a superior immune response to SARS-CoV-2.NPJ Vaccines2022
35241661Antibody escape and global spread of SARS-CoV-2 lineage A.27.Nat Commun2022
33480966Prevalence of SARS-CoV-2 Infection in Children and Their Parents in Southwest Germany.JAMA Pediatr2021
34737266Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants.Nat Commun2021
34413236Rare variant <i>MX1</i> alleles increase human susceptibility to zoonotic H7N9 influenza virus.Science2021
34269676Type I interferon receptor-independent interferon-α induction upon infection with a variety of negative-strand RNA viruses.J Gen Virol2021
34320609Rapid and stable mobilization of CD8<sup>+</sup> T cells by SARS-CoV-2 mRNA vaccine.Nature2021
34122407Macrophages and Dendritic Cells Are Not the Major Source of Pro-Inflammatory Cytokines Upon SARS-CoV-2 Infection.Front Immunol2021
33221383Systemic and mucosal antibody responses specific to SARS-CoV-2 during mild versus severe COVID-19.J Allergy Clin Immunol2021
33184509Characterization of pre-existing and induced SARS-CoV-2-specific CD8<sup>+</sup> T cells.Nat Med2021
32519406Prolonged SARS-CoV-2 shedding and mild course of COVID-19 in a patient after recent heart transplantation.Am J Transplant2020
31773252Mx genes: host determinants controlling influenza virus infection and trans-species transmission.Hum Genet2020
33060197Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.Science2020
33196685Tick-transmitted thogotovirus gains high virulence by a single MxA escape mutation in the viral nucleoprotein.PLoS Pathog2020
33163980Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells.Cell Rep Med2020
32645325The Global Phosphorylation Landscape of SARS-CoV-2 Infection.Cell2020
32416749Using a mouse-adapted A/HK/01/68 influenza virus to analyse the impact of NS1 evolution in codons 196 and 231 on viral replication and virulence.J Gen Virol2020
32522852A Genome-Wide CRISPR-Cas9 Screen Reveals the Requirement of Host Cell Sulfation for Schmallenberg Virus Infection.J Virol2020
31092574Mx1 in Hematopoietic Cells Protects against Thogoto Virus Infection.J Virol2019
31211667Essential Role of Interferon Response in Containing Human Pathogenic Bourbon Virus.Emerg Infect Dis2019
31574080Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins.PLoS Biol2019
29330299Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity.J Biol Chem2018
30081309Equine MX2 is a restriction factor of equine infectious anemia virus (EIAV).Virology2018
29950411Human MxB Protein Is a Pan-herpesvirus Restriction Factor.J Virol2018
29434310Recombinant IFN-γ from the bank vole Myodes glareolus: a novel tool for research on rodent reservoirs of zoonotic pathogens.Sci Rep2018
29709033Viral targeting of TFIIB impairs de novo polymerase II recruitment and affects antiviral immunity.PLoS Pathog2018
28760668RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection.Mol Ther2017
28396461In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein.J Exp Med2017
28490593Evolution and Antiviral Specificities of Interferon-Induced Mx Proteins of Bats against Ebola, Influenza, and Other RNA Viruses.J Virol2017
28641955Molecular identification of novel phlebovirus sequences in European ticks.Ticks Tick Borne Dis2017
28548099Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET.Nat Commun2017
27512061In Vivo Conditions Enable IFNAR-Independent Type I Interferon Production by Peritoneal CD11b+ Cells upon Thogoto Virus Infection.J Virol2016
26609934Interferon but not MxB inhibits foamy retroviruses.Virology2016
25572883Mx GTPases: dynamin-like antiviral machines of innate immunity.Trends Microbiol2015
25829498Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.J Biol Chem2015
25631088The avian-origin PB1 gene segment facilitated replication and transmissibility of the H3N2/1968 pandemic influenza virus.J Virol2015
25704008Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.Cell Host Microbe2015
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Collaborators

Martin Schwemmle
Institute of Virology, Medical Center - University of Freiburg
Co-authored papers 21
Adolfo Garc??a-Sastre
Icahn School of Medicine at Mount Sinai
Co-authored papers 17
Sebastian Weigang
Institute of Virology, Freiburg University Medical Center, University of Freiburg
Co-authored papers 12
Silke Stertz
Institute of Medical Virology, University of Zurich
Co-authored papers 10
Luis Martinez-Sobrido
Texas Biomedical Research Institute
Co-authored papers 7
Sebastian Giese
Institute of Virology, Freiburg University Medical Center, University of Freiburg
Co-authored papers 4
Robert Grosse
University of Freiburg
Co-authored papers 3
Peter Palese
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Lisa Miorin
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Margaret Soucheray
J. David Gladstone Institutes
Co-authored papers 2
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NYU Grossman School of Medicine
Co-authored papers 2
Kirsten Obernier (CM4AI)
University of California San Francisco
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Fred Hutchinson Cancer Center
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Department of Pharmaceutical Chemistry, University of California san francisco
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Harmit S Malik
Fred Hutchinson Cancer Center
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Jyoti Batra
J. David Gladstone Institutes
Co-authored papers 2
Marco Vignuzzi
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
Ruth H??ttenhain
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 2
Dominik Dornfeld
Institute of Virology, Medical Center University of Freiburg
Co-authored papers 2
Kris M White
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
Kevan M Shokat
University of California San Francisco
Co-authored papers 2
Beril Tutuncuoglu
University of California san francisco
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Robyn M Kaake
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Nevan J Krogan (CM4AI)
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Release 1.2