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Author Details

Chris I Newbold
Wellcome Trust Sanger Institute
1981
161
74
PMIDPaper TitleJournal TitlePublished Year
32796922Author Correction: Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria.Nat Microbiol2020
32745123Genomic and transcriptomic evidence for descent from Plasmodium and loss of blood schizogony in Hepatocystis parasites from naturally infected red colobus monkeys.PLoS Pathog2020
30862316Repeated clinical malaria episodes are associated with modification of the immune system in children.BMC Med2019
32055709Evolutionary analysis of the most polymorphic gene family in <i>falciparum</i> malaria.Wellcome Open Res2019
29784978Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria.Nat Microbiol2018
29862326Long read assemblies of geographically dispersed <i>Plasmodium falciparum</i> isolates reveal highly structured subtelomeres.Wellcome Open Res2018
30510775Pre-clinical evaluation of a <i>P. berghei</i>-based whole-sporozoite malaria vaccine candidate.NPJ Vaccines2018
29500236Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals.Genome Res2018
29459671In silico guided reconstruction and analysis of ICAM-1-binding var genes from Plasmodium falciparum.Sci Rep2018
28117441Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution.Nature2017
28165471Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection.Nat Microbiol2017
28430103Genomic Characterization of Recrudescent Plasmodium malariae after Treatment with Artemether/Lumefantrine.Emerg Infect Dis2017
27998271Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification.Malar J2016
28008421A new <i>Plasmodium vivax</i> reference sequence with improved assembly of the subtelomeres reveals an abundance of <i>pir</i> genes.Wellcome Open Res2016
24581555A comprehensive evaluation of assembly scaffolding tools.Genome Biol2014
25203297Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts.Nat Commun2014
25240466Optimized whole-genome amplification strategy for extremely AT-biased template.DNA Res2014
25359557A comprehensive evaluation of rodent malaria parasite genomes and gene expression.BMC Biol2014
23224084Efficient depletion of host DNA contamination in malaria clinical sequencing.J Clin Microbiol2013
24062941The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria.Elife2013
23980881Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation.Mol Microbiol2013
23624527Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia.Nat Genet2013
23710727REAPR: a universal tool for genome assembly evaluation.Genome Biol2013
22384044Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure.PLoS One2012
23133397Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.PLoS Genet2012
22722859Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing.Nature2012
22678431A post-assembly genome-improvement toolkit (PAGIT) to obtain annotated genomes from contigs.Nat Protoc2012
21408201Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.PLoS Pathog2011
21789235An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing.PLoS One2011
21572427Host-mediated regulation of superinfection in malaria.Nat Med2011
21673999Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay.PLoS One2011
20141604New insights into the blood-stage transcriptome of Plasmodium falciparum using RNA-Seq.Mol Microbiol2010
20562415Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.Bioinformatics2010
20227667Functional identification of the Plasmodium centromere and generation of a Plasmodium artificial chromosome.Cell Host Microbe2010
19497936ABACAS: algorithm-based automatic contiguation of assembled sequences.Bioinformatics2009
19687029SnoopCGH: software for visualizing comparative genomic hybridization data.Bioinformatics2009
19747361Plasmodium falciparum infected erythrocytes induce hepcidin (HAMP) mRNA synthesis by peripheral blood mononuclear cells.Br J Haematol2009
19376968Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture.Proc Natl Acad Sci U S A2009
18096748Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum.Genome Res2008
18843368The genome of the simian and human malaria parasite Plasmodium knowlesi.Nature2008
18534600Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children.Int J Parasitol2008
18706102Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1.Malar J2008
18614010Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes.Cell2008
18433451Plasmodium falciparum antigenic variation. Mapping mosaic var gene sequences onto a network of shared, highly polymorphic sequence blocks.Mol Microbiol2008
17159978Genome variation and evolution of the malaria parasite Plasmodium falciparum.Nat Genet2007
17257309Plasmodium falciparum var gene expression is developmentally controlled at the level of RNA polymerase II-mediated transcription initiation.Mol Microbiol2007
17253978Plasmodium cysteine repeat modular proteins 1-4: complex proteins with roles throughout the malaria parasite life cycle.Cell Microbiol2007
17286864Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates.BMC Genomics2007
17467073An approach to classifying sequence tags sampled from Plasmodium falciparum var genes.Mol Biochem Parasitol2007
16622019CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway.J Immunol2006
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Collaborators

Weatherall Institute of Molecular Medicine
Co-authored papers 35
Wellcome Sanger Institute
Co-authored papers 32
Malawi-Liverpool-Wellcome Trust Clinical Research Program
Co-authored papers 23
King Abdullah University of Science and Technology
Co-authored papers 10
Wellcome Trust Sanger Institute
Co-authored papers 6
Co-authored papers 5
Earlham Institute
Co-authored papers 4
European Bioinformatics Institute
Co-authored papers 3
NRC Institute for Marine Biosciences
Co-authored papers 3
The Wellcome Trust Sanger Institute
Co-authored papers 3
University of Washington School of Medicine
Co-authored papers 3
Nursing and Health SciencesMonash UniversityClaytonVictoriaAustralia.
Co-authored papers 2
US Military Malaria Vaccine Program, Naval Medical Research Center
Co-authored papers 2
Edinburgh Clinical Research Facility, University of Edinburgh
Co-authored papers 2
Wellcome Sanger Institute
Co-authored papers 2
Co-authored papers 2
University of Cambridge
Co-authored papers 2
Wellcome Trust Sanger Institute
Co-authored papers 2
Macquarie University
Co-authored papers 1
Big Data Institute, University of Oxford
Co-authored papers 1
University of Guelph
Co-authored papers 1
Burnet Institute
Co-authored papers 1
Center for Biomolecular Science and Engineering, University of California
Co-authored papers 1
Julius-Maximilians-Universitat Wurzburg
Co-authored papers 1
University of Oxford
Co-authored papers 1
University of Oxford
Co-authored papers 1
Co-authored papers 1
Center for Molecular Parasitology, Drexel University College of Medicine
Co-authored papers 1
Eck Institute for Global Health, University of Notre Dame
Co-authored papers 1
Co-authored papers 1