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Author Details

Marc Remke
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
2007
187
65
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36301489CD155 is a putative therapeutic target in medulloblastoma.Clin Transl Oncol2023
37656187Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma.Acta Neuropathol2023
38001143Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures.Nat Commun2023
37582744Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors.Mol Cancer2023
38057328Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells.Cell Death Dis2023
37976029The long non-coding RNA OTX2-AS1 promotes tumor growth and predicts response to BCL-2 inhibition in medulloblastoma.J Neurooncol2023
37215954UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease.Neurooncol Adv2023
37183219Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.J Neurooncol2023
37402719Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.Nat Commun2023
36639156Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.J Immunother Cancer2023
36627300Author Correction: Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.Nat Commun2023
36239995A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma.Clin Cancer Res2023
34810198BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment.Cancer Res2022
35804936WNT/β-Catenin-Mediated Resistance to Glucose Deprivation in Glioblastoma Stem-like Cells.Cancers (Basel)2022
35650266Persister state-directed transitioning and vulnerability in melanoma.Nat Commun2022
35441993Structural damage burden and hypertrophic olivary degeneration in pediatric postoperative cerebellar mutism syndrome.Neurosurg Rev2022
35379801EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma.Cell Death Discov2022
35831316The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.Nat Commun2022
36473869Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.Nat Commun2022
36524349Correction: PINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma.Cancer Res2022
36248154Second-look surgery after pediatric brain tumor resection - Single center analysis of morbidity and volumetric efficacy.Brain Spine2022
35993110Sensitivity towards HDAC inhibition is associated with RTK/MAPK pathway activation in gastric cancer.EMBO Mol Med2022
35866882WNT Medulloblastoma Limbo: How Low Can We Go?Clin Cancer Res2022
36127323Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors.Cell Death Dis2022
36219398Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma.Cancer Res2022
34952462Glutaredoxin 2 promotes SP-1-dependent CSPG4 transcription and migration of wound healing NG2 glia and glioma cells: Enzymatic Taoism.Redox Biol2022
35307743Intratumoral heterogeneity of MYC drives medulloblastoma metastasis and angiogenesis.Neuro Oncol2022
35334498Progenitor cells derived from gene-engineered human induced pluripotent stem cells as synthetic cancer cell alternatives for in vitro pharmacology.Biotechnol J2022
35228525Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation.Cell Death Discov2022
32822486Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma.Neuro Oncol2021
33600825Classical and Variant Merkel Cell Carcinoma Cell Lines Display Different Degrees of Neuroendocrine Differentiation and Epithelial-Mesenchymal Transition.J Invest Dermatol2021
33866410Circular RNA profiling distinguishes medulloblastoma groups and shows aberrant RMST overexpression in WNT medulloblastoma.Acta Neuropathol2021
34584066The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma.Cell Death Dis2021
34628166Longitudinal stability of molecular alterations and drug response profiles in tumor spheroid cell lines enables reproducible analyses.Biomed Pharmacother2021
34079902Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.ACS Cent Sci2021
34359754Identification and Functional Characterization of Novel MYC-Regulated Long Noncoding RNAs in Group 3 Medulloblastoma.Cancers (Basel)2021
34337410Expression of cell type incongruent alpha-cardiac actin 1 subunit in medulloblastoma reveals a novel mechanism for cancer cell survival and control of migration.Neurooncol Adv2021
33945292Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.J Clin Oncol2021
32286280Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.Nat Commun2020
31802583Proteome-Wide Survey of Cysteine Oxidation by Using a Norbornene Probe.Chembiochem2020
32004447Bi-allelic Variants in RALGAPA1 Cause Profound Neurodevelopmental Disability, Muscular Hypotonia, Infantile Spasms, and Feeding Abnormalities.Am J Hum Genet2020
33333810Different Calculation Strategies Are Congruent in Determining Chemotherapy Resistance of Brain Tumors In Vitro.Cells2020
33123073Involvement of CXCL1/CXCR2 During Microglia Activation Following Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Rats.Front Neurol2020
32642697Interferon-β exposure induces a fragile glioblastoma stem cell phenotype with a transcriptional profile of reduced migratory and MAPK pathway activity.Neurooncol Adv2020
32585856YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA.Int J Mol Sci2020
32245394KLF4<sup>K409Q</sup>-mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment.Acta Neuropathol Commun2020
32296180Germline Elongator mutations in Sonic Hedgehog medulloblastoma.Nature2020
32346009N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma.Sci Rep2020
32451331A Cell-Based MAPK Reporter Assay Reveals Synergistic MAPK Pathway Activity Suppression by MAPK Inhibitor Combination in <i>BRAF</i>-Driven Pediatric Low-Grade Glioma Cells.Mol Cancer Ther2020
30530705The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma.Clin Cancer Res2019
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Collaborators

Michael D Taylor
The Hospital for Sick Children
Co-authored papers 100
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 74
Andrey Korshunov
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 62
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 50
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 47
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 45
Daniel Picard
Groupe Hospitalier Universitaire Pitie-Salpetriere
Co-authored papers 45
Peter Lichter
German Cancer Research Center (DKFZ)
Co-authored papers 35
Cynthia Hawkins
The Hospital for Sick Children
Co-authored papers 34
David T W Jones
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 32
James T Rutka
Hospital for Sick Children
Co-authored papers 29
Guido Reifenberger
Heinrich Heine University
Co-authored papers 29
Uri Tabori
Co-authored papers 28
Eric Bouffet
The Hospital for Sick Children
Co-authored papers 28
Stefan Rutkowski
University Medical Center Hamburg-Eppendorf
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David J H Shih
University of Texas MD Anderson Cancer Center Houston
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Andreas von Deimling
Co-authored papers 26
Olaf Witt
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 24
Nada Jabado
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 24
Andreas E Kulozik
Co-authored papers 22
Peter B Dirks
The Hospital for Sick Children, University of Toronto
Co-authored papers 21
Till Milde
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 20
Hendrik Witt
Co-authored papers 20
Adrian M Dubuc
Dana-Farber Cancer Institute
Co-authored papers 20
Stephen C Mack
St Jude Children's Research Hospital
Co-authored papers 19
Nan Qin
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 18
Torsten Pietsch
Co-authored papers 18
David Malkin
Hospital for Sick Children
Co-authored papers 18
Scott L Pomeroy
Harvard Medical School
Co-authored papers 18
Marina Ryzhova
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