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Author Details

April Hartley
MRC Integrative Epidemiology Unit at the University of Bristol
2016
29
12
PMIDPaper TitleJournal TitlePublished Year
36821633Strategies to investigate and mitigate collider bias in genetic and Mendelian randomisation studies of disease progression.PLoS Genet2023
37619450The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses.EBioMedicine2023
37133737Age-specific effects of weight-based body size on fracture risk in later life: a lifecourse Mendelian randomisation study.Eur J Epidemiol2023
37433298Genetic underpinning of the comorbidity between type 2 diabetes and osteoarthritis.Am J Hum Genet2023
37096546Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization.Arthritis Rheumatol2023
36662418A Genome-Wide Association Study Meta-Analysis of Alpha Angle Suggests Cam-Type Morphology May Be a Specific Feature of Hip Osteoarthritis in Older Adults.Arthritis Rheumatol2023
34897459Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index.Int J Epidemiol2022
35583096Adjusting for collider bias in genetic association studies using instrumental variable methods.Genet Epidemiol2022
36248277A Guide for Understanding and Designing Mendelian Randomization Studies in the Musculoskeletal Field.JBMR Plus2022
35933372High bone mass and cam morphology are independently related to hip osteoarthritis: findings from the High Bone Mass cohort.BMC Musculoskelet Disord2022
33397451Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual.Genome Biol2021
33538965Osteoarthritis: Insights Offered by the Study of Bone Mass Genetics.Curr Osteoporos Rep2021
34169346Socio-economic inequalities in fragility fracture incidence: a systematic review and meta-analysis of 61 observational studies.Osteoporos Int2021
33407835Increased development of radiographic hip osteoarthritis in individuals with high bone mass: a prospective cohort study.Arthritis Res Ther2021
33027520Mendelian randomization provides evidence for a causal effect of higher serum IGF-1 concentration on risk of hip and knee osteoarthritis.Rheumatology (Oxford)2021
31525280A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD-Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis.J Bone Miner Res2020
31667854Metabolomics analysis in adults with high bone mass identifies a relationship between bone resorption and circulating citrate which replicates in the general population.Clin Endocrinol (Oxf)2020
32417557Individuals with high bone mass have increased progression of radiographic and clinical features of knee osteoarthritis.Osteoarthritis Cartilage2020
32514764Correction to: Lean mass and lower limb muscle function in relation to hip strength, geometry and fracture risk indices in community-dwelling older women.Osteoporos Int2020
30552442Lean mass and lower limb muscle function in relation to hip strength, geometry and fracture risk indices in community-dwelling older women.Osteoporos Int2019
31082498Older age at initiation of antiretroviral therapy predicts low bone mineral density in children with perinatally-infected HIV in Zimbabwe.Bone2019
29237047Correlates of high-impact physical activity measured objectively in older British adults.J Public Health (Oxf)2018
29182712Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity.J Gerontol A Biol Sci Med Sci2018
29028919Physical Activity Producing Low, but Not Medium or Higher, Vertical Impacts Is Inversely Related to BMI in Older Adults: Findings From a Multicohort Study.J Gerontol A Biol Sci Med Sci2018
27798733A novel accelerometer-based method to describe day-to-day exposure to potentially osteogenic vertical impacts in older adults: findings from a multi-cohort study.Osteoporos Int2017
29134173Associations of lifetime walking and weight bearing exercise with accelerometer-measured high impact physical activity in later life.Prev Med Rep2017
28860427Feasibility and acceptability of using jumping mechanography to detect early components of sarcopenia in community-dwelling older women.J Musculoskelet Neuronal Interact2017
27966105Habitual levels of higher, but not medium or low, impact physical activity are positively related to lower limb bone strength in older women: findings from a population-based study using accelerometers to classify impact magnitude.Osteoporos Int2017
26421605Characterization of Vertical Accelerations Experienced by Older People Attending an Aerobics Class Designed to Produce High Impacts.J Aging Phys Act2016
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Collaborators

Jon H Tobias
Co-authored papers 22
George Davey Smith
University of Bristol
Co-authored papers 8
Ahmed Elhakeem
Bristol Medical School, University of Bristol
Co-authored papers 6
Eleftheria Zeggini
Co-authored papers 5
Elaine M Dennison
Co-authored papers 4
John P Kemp
Co-authored papers 4
Cyrus Cooper
Co-authored papers 4
Andrew Wong
Co-authored papers 4
Lorraine Southam
Co-authored papers 3
Joyce B J van Meurs
Co-authored papers 3
David M Evans
Medical Research Council Integrative Epidemiology Unit at the University of Bristol
Co-authored papers 2
Debbie A Lawlor
Bristol Medical School, University of Bristol
Co-authored papers 2
Eleanor Wheeler
Co-authored papers 1
Gregory P Way
Broad Institute of MIT and Harvard
Co-authored papers 1
Heidi J Kalkwarf
Cincinnati Children's Hospital Medical Center Cincinnati
Co-authored papers 1
Patricia A Peyser
School of Public Health, University of Michigan ann arbor
Co-authored papers 1
George Dedoussis
Co-authored papers 1
Vicente Gilsanz
Center for Endocrinology, Children's Hospital Los Angeles
Co-authored papers 1
Shana E McCormack
The Children's Hospital of Philadelphia Division of Endocrinology and Diabetes
Co-authored papers 1
Matthew A Brown
Co-authored papers 1
Nancy E Lane
Center for Musculoskeletal Health, University of California Davis School of Medicine
Co-authored papers 1
Frank Dudbridge
Co-authored papers 1
Avan Aihie Sayer
Co-authored papers 1
Nicholas J Wareham
Co-authored papers 1
Sumei Lu
China National Center for Biotechnology Development
Co-authored papers 1
Babette S Zemel
Children's Hospital of Philadelphia
Co-authored papers 1
Robert C Kaplan
Co-authored papers 1
Jonathan A Mitchell
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Andrew D Wells
Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia
Co-authored papers 1
Diana L Cousminer
Children's Hospital of Philadelphia
Co-authored papers 1
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