Author details

Full Name

Ronglai Shen

Affiliation

ORCID

Career Start Year

2002

Papers

145

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37162890	Uncovering the hidden structure of dynamic T cell composition in peripheral blood during cancer immunotherapy: a topic modeling approach.	bioRxiv	2023
37671017	A topic modeling approach reveals the dynamic T cell composition of peripheral blood during cancer immunotherapy.	Cell Rep Methods	2023
37667855	Integration of peripheral blood- and tissue-based biomarkers of response to immune checkpoint blockade in urothelial carcinoma.	J Pathol	2023
37786694	Adaptation of a Mutual Exclusivity Framework to Identify Driver Mutations within Biological Pathways.		2023
36969913	Predicting Cancer Risk from Germline Whole-exome Sequencing Data Using a Novel Context-based Variant Aggregation Approach.		2023
37384866	Clinical and Genomic Features of Response and Toxicity to Sotorasib in a Real-World Cohort of Patients With Advanced <i>KRAS G12C</i>-Mutant Non-Small Cell Lung Cancer.	JCO Precis Oncol	2023
36805567	Methylation of nonessential genes in cutaneous melanoma - Rule Out hypothesis.	Melanoma Res	2023
36926987	Pathway Alterations in Stage II/III Primary Melanoma.	JCO Precis Oncol	2023
37487667	Efficacy of PD-(L)1 blockade monotherapy compared with PD-(L)1 blockade plus chemotherapy in first-line PD-L1-positive advanced lung adenocarcinomas: a cohort study.	J Immunother Cancer	2023
37223888	The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non-Small Cell Lung Cancer.	Clin Cancer Res	2023
35220606	Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies.	J Pathol	2022
36044468	Bioinformatically Expanded Next-Generation Sequencing Analysis Optimizes Identification of Therapeutically Relevant MET Copy Number Alterations in >50,000 Tumors.	Clin Cancer Res	2022
36357680	Overall survival with circulating tumor DNA-guided therapy in advanced non-small-cell lung cancer.	Nat Med	2022
35699480	Genomic Determinants of Early Recurrences in Low-Stage, Low-Grade Endometrioid Endometrial Carcinoma.	J Natl Cancer Inst	2022
35751811	FACETS: Fraction and Allele-Specific Copy Number Estimates from Tumor Sequencing.	Methods Mol Biol	2022
35876628	Landscape of mutations in early stage primary cutaneous melanoma: An InterMEL study.	Pigment Cell Melanoma Res	2022
36505421	Increased tumor glycolysis is associated with decreased immune infiltration across human solid tumors.		2022
34734967	Implications of Selection Bias Due to Delayed Study Entry in Clinical Genomic Studies.	JAMA Oncol	2022
35235413	Same-Cell Co-Occurrence of RAS Hotspot and BRAF V600E Mutations in Treatment-Naive Colorectal Cancer.	JCO Precis Oncol	2022
35027431	Accounting for Delayed Entry in Analyses of Overall Survival in Clinico-Genomic Databases.	Cancer Epidemiology Biomarkers and Prevention	2022
34949653	Cancer-Causative Mutations Occurring in Early Embryogenesis.	Cancer Discov	2022
34433638	LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade.	Sci Transl Med	2021
33664338	Bayesian network-driven clustering analysis with feature selection for high-dimensional multi-modal molecular data.	Scientific Reports	2021
34031376	Mining mutation contexts across the cancer genome to map tumor site of origin.	Nature Communications	2021
34332931	The use of a next-generation sequencing-derived machine-learning risk-prediction model (OncoCast-MPM) for malignant pleural mesothelioma: a retrospective study.	Lancet Digit Health	2021
34311346	Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions.	Lung Cancer	2021
33355651	A Genomic-Pathologic Annotated Risk Model to Predict Recurrence in Early-Stage Lung Adenocarcinoma.	JAMA Surg	2021
32914442	Using the "Hidden" genome to improve classification of cancer types.	Biometrics	2021
33172896	<i>MET</i> Exon 14-altered Lung Cancers and MET Inhibitor Resistance.	Clin Cancer Res	2021
34625293	Corrigendum to "Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions" [Lung Cancer 159 (2021) 66-73].	Lung Cancer	2021
34671755	Pan-cancer analysis of pathway-based gene expression pattern at the individual level reveals biomarkers of clinical prognosis.	Cell Rep Methods	2021
34718237	Exome-Wide Pan-Cancer Analysis of Germline Variants in 8,719 Individuals Finds Little Evidence of Rare Variant Associations.	Human Heredity	2021
34433650	Genome-Derived Classification Signature for Ampullary Adenocarcinoma to Improve Clinical Cancer Care.	Clinical Cancer Research	2021
33264619	Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer.	Cell Rep	2020
32119081	Radiation Treatment, ATM, BRCA1/2, and CHEK2*1100delC Pathogenic Variants and Risk of Contralateral Breast Cancer.	J Natl Cancer Inst	2020
32231720	Combined Preoperative LMR and CA125 for Prognostic Assessment of Ovarian Cancer.	Journal of Cancer	2020
32213539	HER2-Mediated Internalization of Cytotoxic Agents in <i>ERBB2</i> Amplified or Mutant Lung Cancers.	Cancer Discov	2020
32483290	Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy.	Nat Genet	2020
32643855	Human genes differ by their UV sensitivity estimated through analysis of UV-induced silent mutations in melanoma.	Hum Mutat	2020
32864625	Alterations in <i>PTEN</i> and <i>ESR1</i> promote clinical resistance to alpelisib plus aromatase inhibitors.	Nat Cancer	2020
33272320	Pan-cancer identification of clinically relevant genomic subtypes using outcome-weighted integrative clustering.	Genome Med	2020
31347936	Lessons learned from routine, targeted assessment of liquid biopsies for <i>EGFR</i> T790M resistance mutation in patients with <i>EGFR</i> mutant lung cancers.	Acta Oncol	2019
31796730	Using somatic variant richness to mine signals from rare variants in the cancer genome.	Nat Commun	2019
31768066	High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants.	Nat Med	2019
32914032	Radiogenomics Analysis of Intratumor Heterogeneity in a Patient With High-Grade Serous Ovarian Cancer.	JCO Precis Oncol	2019
30171176	A Leukocyte Infiltration Score Defined by a Gene Signature Predicts Melanoma Patient Prognosis.	Mol Cancer Res	2019
30526008	Variance prior specification for a basket trial design using Bayesian hierarchical modeling.	Clinical Trials	2019
30643254	Tumor mutational load predicts survival after immunotherapy across multiple cancer types.	Nat Genet	2019
31228622	Concurrent RB1 and TP53 Alterations Define aÂ Subset of EGFR-Mutant Lung Cancers at risk forÂ Histologic Transformation and Inferior Clinical Outcomes.	J Thorac Oncol	2019
30863842	Using association signal annotations to boost similarity network fusion.		2019