Author details

Full Name

Alan G Hinnebusch

Affiliation

Eunice Kennedy Shriver National Institute of Child Health and Human Development

ORCID

Career Start Year

1977

Papers

282

H Index

Expertise

CM4AI Collaborator

Trey Ideker (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37986768	Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system.	bioRxiv	2024
36864781	Differential requirements for Gcn5 and NuA4 HAT activities in the starvation-induced versus basal transcriptomes.	Nucleic Acids Res	2023
37986989	Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control <i>in vivo</i>.	bioRxiv	2023
37043534	Differential requirements for P stalk components in activating yeast protein kinase Gcn2 by stalled ribosomes during stress.	Proc Natl Acad Sci U S A	2023
37439347	mRNA decapping activators Pat1 and Dhh1 regulate transcript abundance and translation to tune cellular responses to nutrient availability.	Nucleic Acids Res	2023
37433636	Translational regulation by uORFs and start codon selection stringency.	Genes Dev	2023
37266577	Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability.	Elife	2023
36711592	Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability.	bioRxiv	2023
34791232	uS5/Rps2 residues at the 40S ribosome entry channel enhance initiation at suboptimal start codons in vivo.	Genetics	2022
35793348	Distinct functions of three chromatin remodelers in activator binding and preinitiation complex assembly.	PLoS Genet	2022
33290553	Correction: Chromatin remodeler Ino80C acts independently of H2A.Z to evict promoter nucleosomes and stimulate transcription of highly expressed genes in yeast.	Nucleic Acids Res	2021
33764298	Reprogramming of translation in yeast cells impaired for ribosome recycling favors short, efficiently translated mRNAs.	Elife	2021
34946015	Down-Regulation of Yeast Helicase Ded1 by Glucose Starvation or Heat-Shock Differentially Impairs Translation of Ded1-Dependent mRNAs.	Microorganisms	2021
34648019	Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.	Nucleic Acids Res	2021
32469309	Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo.	Elife	2020
31915290	eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide.	RNA	2020
32663283	Chromatin remodeler Ino80C acts independently of H2A.Z to evict promoter nucleosomes and stimulate transcription of highly expressed genes in yeast.	Nucleic Acids Res	2020
32589964	Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes.	Mol Cell	2020
32955564	eIF2Î± interactions with mRNA control accurate start codon selection by the translation preinitiation complex.	Nucleic Acids Res	2020
30576497	A network of eIF2Î² interactions with eIF1 and Met-tRNAi promotes accurate start codon selection by the translation preinitiation complex.	Nucleic Acids Res	2019
31810458	Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae.	BMC Biol	2019
31299079	Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo.	Nucleic Acids Res	2019
31335872	Correction: Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo.	PLoS Genet	2019
29281028	Please do not recycle! Translation reinitiation in microbes and higher eukaryotes.	FEMS Microbiol Rev	2018
30146315	Tma64/eIF2D, Tma20/MCT-1, and Tma22/DENR Recycle Post-termination 40S Subunits InÂ Vivo.	Mol Cell	2018
30475211	Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.	Elife	2018
30281017	Yeast Ded1 promotes 48S translation pre-initiation complex assembly in an mRNA-specific and eIF4F-dependent manner.	Elife	2018
30532217	Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo.	PLoS Genet	2018
29666249	eIF1 Loop 2 interactions with Met-tRNA<sub>i</sub> control the accuracy of start codon selection by the scanning preinitiation complex.	Proc Natl Acad Sci U S A	2018
29628310	Gcn4 Binding in Coding Regions Can Activate Internal and Canonical 5' Promoters in Yeast.	Mol Cell	2018
29785963	SWI/SNF and RSC cooperate to reposition and evict promoter nucleosomes at highly expressed genes in yeast.	Genes Dev	2018
29192585	Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity.	Elife	2017
28169832	Interface between 40S exit channel protein uS7/Rps5 and eIF2Î± modulates start codon recognition in vivo.	Elife	2017
28223523	Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons.	Proc Natl Acad Sci U S A	2017
28297669	Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.	Cell Rep	2017
28442192	Structural Insights into the Mechanism of Scanning and Start Codon Recognition in Eukaryotic Translation Initiation.	Trends Biochem Sci	2017
29206102	eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast.	Elife	2017
27313038	Translational control by 5'-untranslated regions of eukaryotic mRNAs.	Science	2016
26602697	Genome-wide cooperation by HAT Gcn5, remodeler SWI/SNF, and chaperone Ydj1 in promoter nucleosome eviction and transcriptional activation.	Genome Res	2016
27782884	Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex.	Elife	2016
27601676	eIF4B stimulates translation of long mRNAs with structured 5' UTRs and low closed-loop potential but weak dependence on eIF4G.	Proc Natl Acad Sci U S A	2016
25780171	Translational control 1995-2015: unveiling molecular underpinnings and roles in human biology.	RNA	2015
26276635	Rli1/ABCE1 Recycles Terminating Ribosomes and Controls Translation Reinitiation in 3'UTRs In Vivo.	Cell	2015
26134896	The Î²-hairpin of 40S exit channel protein Rps5/uS7 promotes efficient and accurate translation initiation in vivo.	Elife	2015
26212456	Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.	Mol Cell	2015
26122911	Genome-wide analysis of translational efficiency reveals distinct but overlapping functions of yeast DEAD-box RNA helicases Ded1 and eIF4A.	Genome Res	2015
26023119	Cell biology. Blocking stress response for better memory?	Science	2015
25990728	Eukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating Pi release and conformational transitions of the preinitiation complex.	Nucleic Acids Res	2015
25695491	Interaction between the tRNA-binding and C-terminal domains of Yeast Gcn2 regulates kinase activity in vivo.	PLoS Genet	2015
25670678	Conformational changes in the P site and mRNA entry channel evoked by AUG recognition in yeast translation preinitiation complexes.	Nucleic Acids Res	2015

1 - 50 of 282

Jason Gabunilas

University of California Los Angeles

Career Start Year 2014

Number of shared co-authors 0

Carolyn Jones

University of Cambridge

Career Start Year 2012

Number of shared co-authors 0

Lydia M Castelli

Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield

Career Start Year 2007

Number of shared co-authors 0

Onn Brandman

Stanford University

Career Start Year 2005

Number of shared co-authors 0

Ajay A Vashisht

David Geffen School of Medicine, University of California los angeles

Career Start Year 2005

Number of shared co-authors 0

Megan Bergkessel

University of Dundee

Career Start Year 2004

Number of shared co-authors 1

Rebecca L Hurto

University of Michigan Medical School ann arbor

Career Start Year 2004

Number of shared co-authors 0

Masaaki Sokabe

College of Biological Sciences, University of California davis

Career Start Year 2002

Number of shared co-authors 1

Ivan Topisirovic

McGill University

Career Start Year 2001

Number of shared co-authors 1

Ludivine Wacheul

Universite libre de Bruxelles (ULB)

Career Start Year 2001

Number of shared co-authors 1

Ashkan Golshani

Ottawa Institute of Systems Biology, Carleton University

Career Start Year 1997

Number of shared co-authors 1

Christopher S Fraser

College of Biological Sciences, University of California davis

Career Start Year 1997

Number of shared co-authors 1

Bertrand Cosson

Universite Paris Cite, CNRS

Career Start Year 1997

Number of shared co-authors 1

V??ronique Alban??se

Universite Paris Cite, CNRS, Institut Jacques Monod

Career Start Year 1996

Number of shared co-authors 0

James A Wohlschlegel

David Geffen School of Medicine, University of California Los Angeles

Career Start Year 1996

Number of shared co-authors 1

Minkyu Kim

University of California san francisco

Career Start Year 1995

Number of shared co-authors 1

Denis L J Lafontaine

Universite libre de Bruxelles (ULB)

Career Start Year 1994

Number of shared co-authors 1

Kristian E Baker

Case Western Reserve University School of Medicine

Career Start Year 1993

Number of shared co-authors 0

Svetlana Dokudovskaya

CNRS UMR9018, Institut Gustave Roussy, Universite Paris-Saclay

Career Start Year 1992

Number of shared co-authors 1

Jonathan S Weissman

Whitehead Institute for Biomedical Research

Career Start Year 1991

Number of shared co-authors 2

Martin Pospisek

Charles University

Career Start Year 1991

Number of shared co-authors 0

J??rg B??hler

University College London

Career Start Year 1991

Number of shared co-authors 2

Won-Ki Huh

Seoul National University

Career Start Year 1991

Number of shared co-authors 1

Erin K O'Shea

Howard Hughes Medical Institute

Career Start Year 1989

Number of shared co-authors 0

Stephen Buratowski

Harvard Medical School

Career Start Year 1988

Number of shared co-authors 3

Maria C Costanzo

The Broad Institute of Harvard and MIT

Career Start Year 1984

Number of shared co-authors 1

R??my Bordonn??

Institut de Genetique Moleculaire de Montpellier, CNRS

Career Start Year 1980

Number of shared co-authors 0

Pamela A Silver

Harvard Medical School

Career Start Year 1979

Number of shared co-authors 1

Jack F Greenblatt

College Street, University of Toronto

Career Start Year 1969

Number of shared co-authors 7

Christine Guthrie

University of California san francisco

Career Start Year 1967

Number of shared co-authors 2

row(s) 1 - 30 of 30

Hongen Zhang

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Co-authored papers 8

Jun Qin

Co-authored papers 4

Yoshihiro Nakatani

Dana Farber Cancer Institute

Co-authored papers 4

Michael G Katze

University of Washington

Co-authored papers 3

Ronda J Rolfes

Co-authored papers 3

David Maag

Co-authored papers 3

Stephen K Burley

The State University of New Jersey

Co-authored papers 2

Yuliya Gordiyenko

University of Oxford

Co-authored papers 2

Allan Jacobson

Co-authored papers 2

Bing Li

Co-authored papers 2

Anton A Komar

Center for Gene Regulation in Health and Disease, Cleveland State University

Co-authored papers 1

Michael C Jewett

Northwestern University

Co-authored papers 1

Bernhard Horsthemke

Co-authored papers 1

David Ron

Cambridge Institute for Medical Research, University of Cambridge

Co-authored papers 1

Riccardo Pellarin

CNRS UMR 5086 and Universite Claude Bernard Lyon 1

Co-authored papers 1

Ivan Sadowski

University of British Columbia

Co-authored papers 1

Florian Stengel

University of Konstanz Universitatsstrasse 10

Co-authored papers 1

Gregory Stephanopoulos

Massachusetts Institute of Technology

Co-authored papers 1

Jens Nielsen

Chalmers University of Technology

Co-authored papers 1

Dietmar R Lohmann

Institute of Human Genetics, University Hospital Essen, University Duisburg-Essen

Co-authored papers 1

Paul W Sternberg

California Institute of Technology

Co-authored papers 1

Jesper Q Svejstrup

Panum Institute, University of Copenhagen

Co-authored papers 1

Takashi Nagata

Institute of Advanced Energy, Kyoto University

Co-authored papers 1

Maciek R Antoniewicz

Massachusetts Institute of Technology

Co-authored papers 1

Sebasti??n Ch??vez

Universidad de Sevilla

Co-authored papers 1

Michael Dean

National Cancer Institute

Co-authored papers 1

Robert G Roeder

the Rockefeller University

Co-authored papers 1

Frank C P Holstege

Princess Maxima Center for Pediatric Oncology

Co-authored papers 1

Tsuyoshi Miyake

University of Virginia School of Medicine

Co-authored papers 1

Mark Johnston

University of Colorado School of Medicine

Co-authored papers 1

1 - 30

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