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Author Details

Ephraim L Tsalik
Duke University School of Medicine
1998
90
27
PMIDPaper TitleJournal TitlePublished Year
37815489Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients With Pneumonia: A Prospective Observational Study.Clin Infect Dis2024
36262037Clinically Adjudicated Reference Standards for Evaluation of Infectious Diseases Diagnostics.Clin Infect Dis2023
37961671Peripheral Transcriptomics in Acute and Long-Term Kidney Dysfunction in SARS-CoV2 Infection.medRxiv2023
37081034Author Correction: Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion.Sci Rep2023
37066874Viewing both sides of the coin for infectious disease diagnosis.J Clin Invest2023
37395655RADx-UP Testing Core: Access to COVID-19 Diagnostics in Community-Engaged Research with Underserved Populations.J Clin Microbiol2023
36806137Screening tools for predicting mortality of adults with suspected sepsis: an international sepsis cohort validation study.BMJ Open2023
36936082Blood RNA alternative splicing events as diagnostic biomarkers for infectious disease.Cell Rep Methods2023
34463708Envisioning Future Urinary Tract Infection Diagnostics.Clin Infect Dis2022
35411343Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion.Res Sq2022
35810186Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion.Sci Rep2022
36549275Multi-objective optimization identifies a specific and interpretable COVID-19 host response signature.Cell Syst2022
36178298Host Gene Expression to Predict Sepsis Progression.Crit Care Med2022
35964237A New Era in Host Response Biomarkers to Guide Precision Medicine for Infectious Diseases.J Pediatric Infect Dis Soc2022
35899182SARS-CoV-2 reinfection across a spectrum of immunological states.Health Sci Rep2022
35184750Systematic comparison of published host gene expression signatures for bacterial/viral discrimination.Genome Med2022
32979932A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study.Lancet Infect Dis2021
33597532Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.Nat Commun2021
33591001Sepsis Subclasses: A Framework for Development and Interpretation.Crit Care Med2021
33588438Antibacterial Resistance Leadership Group 2.0: Back to Business.Clin Infect Dis2021
34888402Comparing the Diagnostic Accuracy of Clinician Judgment to a Novel Host Response Diagnostic for Acute Respiratory Illness.Open Forum Infect Dis2021
34905580A comparison of host response strategies to distinguish bacterial and viral infection.PLoS One2021
34586364Assessment of the Feasibility of Using Noninvasive Wearable Biometric Monitoring Sensors to Detect Influenza and the Common Cold Before Symptom Onset.JAMA Netw Open2021
34777354The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood.Front Immunol2021
34105359Heparin-based blood purification attenuates organ injury in baboons with <i>Streptococcus pneumoniae</i> pneumonia.Am J Physiol Lung Cell Mol Physiol2021
33938716Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test.Crit Care Med2021
34001247An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.Genome Med2021
34225776The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches.Genome Med2021
33462581Validation of a Host Gene Expression Test for Bacterial/Viral Discrimination in Immunocompromised Hosts.Clin Infect Dis2021
31157863Average Weighted Accuracy: Pragmatic Analysis for a Rapid Diagnostics in Categorizing Acute Lung Infections (RADICAL) Study.Clin Infect Dis2020
31734695Simultaneous Evaluation of Diagnostic Assays for Pharyngeal and Rectal Neisseria gonorrhoeae and Chlamydia trachomatis Using a Master Protocol.Clin Infect Dis2020
33398303An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.medRxiv2020
33300002Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity.bioRxiv2020
32743603Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches.medRxiv2020
32617371Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population.Open Forum Infect Dis2020
32247863Analytical Evaluation of the Abbott RealTime CT/NG Assay for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Rectal and Pharyngeal Swabs.J Mol Diagn2020
30958855A host gene expression approach for identifying triggers of asthma exacerbations.PLoS One2019
34150923Rapid, Sample-to-Answer Host Gene Expression Test to Diagnose Viral Infection.Open Forum Infect Dis2019
31660864Direct-from-blood RNA sequencing identifies the cause of post-bronchoscopy fever.BMC Infect Dis2019
31353133Host-Based Diagnostics for Acute Respiratory Infections.Clin Ther2019
31631046Validation of a host response test to distinguish bacterial and viral respiratory infection.EBioMedicine2019
31276007A Decade On: Systematic Review of ClinicalTrials.gov Infectious Disease Trials, 2007-2017.Open Forum Infect Dis2019
30707740Pilot study of myocardial ischemia-induced metabolomic changes in emergency department patients undergoing stress testing.PLoS One2019
29537985Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.Crit Care Med2018
30158197Pediatric Antibacterial and Antifungal Trials From 2007 to 2017.Pediatrics2018
29939801The host response as a tool for infectious disease diagnosis and management.Expert Rev Mol Diagn2018
30459950Evaluating the discriminating capacity of cell death (apoptotic) biomarkers in sepsis.J Intensive Care2018
30619110A miRNA Host Response Signature Accurately Discriminates Acute Respiratory Infection Etiologies.Front Microbiol2018
30356117A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection.Nat Commun2018
29449546A community approach to mortality prediction in sepsis via gene expression analysis.Nat Commun2018
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Collaborators

National Institutes of Health
Co-authored papers 41
Duke University School of Medicine
Co-authored papers 22
Rady Children's Institute for Genomic Medicine
Co-authored papers 15
Milken Institute School of Public Health, George Washington University
Co-authored papers 7
University of Cincinnati College of Medicine
Co-authored papers 3
Duke University
Co-authored papers 3
Inflammatix Inc.
Co-authored papers 3
Children's Hospital Oakland Research Institute
Co-authored papers 3
University of Sydney Nepean Clinical School, Nepean Hospital
Co-authored papers 3
Center for Genomic and Computational Biology
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Cornell University
Co-authored papers 2
Clinical Research
Co-authored papers 2
Beth Israel Deaconess Medical Center
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
The Warren Alpert Medical School of Brown University/Rhode Island Hospital
Co-authored papers 2
University of Virginia School of Medicine
Co-authored papers 2
University of Oxford
Co-authored papers 2
Duke University School of Medicine
Co-authored papers 2
Lewis-Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 2
Brigham and Women's Hospital
Co-authored papers 2
Durham VA Healthcare System and Duke University
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F. Hoffmann-La Roche Ltd
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University of Michigan Health System ann arbor
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Massachusetts General Hospital, Harvard School of Medicine,
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Boston Children's Hospital, Harvard Medical School
Co-authored papers 1