Author details

Full Name

Sebastian Bender

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
29489754	The landscape of genomic alterations across childhood cancers.	Nature	2018
27635046	Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas.	Cancer Res	2016
27213425	Pediatric and Adult High-Grade Glioma Stem Cell Culture Models Are Permissive to Lytic Infection with Parvovirus H-1.	Viruses	2016
26856307	Telomere dysfunction and chromothripsis.	Int J Cancer	2016
27556362	Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma.	Oncotarget	2016
26424849	Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine.	Nucleic Acids Research	2015
25752754	Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers.	Acta Neuropathol	2015
25808873	Chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer.	Cancer Research	2015
26271101	The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis.	EMBO Journal	2015
24553142	Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.	Nature	2014
24457416	Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.	Nat Rev Cancer	2014
23852775	Oncolytic effects of parvovirus H-1 in medulloblastoma are associated with repression of master regulators of early neurogenesis.	Int J Cancer	2014
24481334	Guanine nucleotide-binding protein Î± subunit hypofunction in children with short stature and disproportionate shortening of the 4th and 5th metacarpals.	Horm Res Paediatr	2014
25104850	p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas.	Hum Mol Genet	2014
24651015	Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.	Cancer Cell	2014
24183680	Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas.	Cancer Cell	2013
23817572	Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.	Nat Genet	2013
22265402	Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations.	Cell	2012
22832583	Dissecting the genomic complexity underlying medulloblastoma.	Nature	2012
23079654	Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.	Cancer Cell	2012
23284304	Dnmt3a protects active chromosome domains against cancer-associated hypomethylation.	PLoS Genetics	2012
21874002	Whole-genome sequencing of multiple Arabidopsis thaliana populations.	Nat Genet	2011
21273290	FGFR3 is a target of the homeobox transcription factor SHOX in limb development.	Hum Mol Genet	2011
21424530	Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma.	Acta Neuropathol	2011
21493867	The transcription factor evi-1 is overexpressed, promotes proliferation, and is prognostically unfavorable in infratentorial ependymomas.	Clin Cancer Res	2011
21911727	FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma.	J Clin Oncol	2011
21840481	Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.	Cancer Cell	2011
20516456	Molecular staging of intracranial ependymoma in children and adults.	J Clin Oncol	2010
20924110	Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma.	Cancer Res	2010