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Author Details

Denis Wirtz
Johns Hopkins University
1993
229
75
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37425743Small extracellular vesicles promote stiffness-mediated metastasis.bioRxiv2024
37292712Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers.bioRxiv2024
36773599Tissue clearing and 3D reconstruction of digitized, serially sectioned slides provide novel insights into pancreatic cancer.Med2023
37586148Withdrawal: Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts.J Biol Chem2023
37546904Mechano-induced homotypic patterned domain formation by monocytes.bioRxiv2023
37080163Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces.Cell Syst2023
37205503Age-related increases in IGFBP2 increase melanoma cell invasion and lipid synthesis.bioRxiv2023
37333379Precision-engineered biomimetics: the human fallopian tube.bioRxiv2023
35247897Editor's Note: Collagen Prolyl Hydroxylases Are Essential for Breast Cancer Metastasis.Cancer Res2022
35841152Engineered bispecific antibodies targeting the interleukin-6 and -8 receptors potently inhibit cancer cell migration and tumor metastasis.Mol Ther2022
35476447Mechanical tension mobilizes Lgr6<sup>+</sup> epidermal stem cells to drive skin growth.Sci Adv2022
35537336Deep learning identification of stiffness markers in breast cancer.Biomaterials2022
35385679Cell Trafficking at the Intersection of the Tumor-Immune Compartments.Annu Rev Biomed Eng2022
36280719CODA: quantitative 3D reconstruction of large tissues at cellular resolution.Nat Methods2022
36077686Lung Cancer Recurrence Risk Prediction through Integrated Deep Learning Evaluation.Cancers (Basel)2022
33469145Fractional re-distribution among cell motility states during ageing.Commun Biol2021
33753940Extracellular vesicles in immunomodulation and tumor progression.Nat Immunol2021
34686696Use of the p-values as a size-dependent function to address practical differences when analyzing large datasets.Sci Rep2021
33949714Characterization of tumor-associated macrophages in prostate cancer transgenic mouse models.Prostate2021
33170810Emergency seed funding for COVID-19 research: lessons from Johns Hopkins University.J Clin Invest2021
33424024A robust unsupervised machine-learning method to quantify the morphological heterogeneity of cells and nuclei.Nat Protoc2021
32483112Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming.Nat Commun2020
33532593Effect of an alkyl spacer on the morphology and internalization of MUC1 aptamer-naphthalimide amphiphiles for targeting and imaging triple negative breast cancer cells.Bioeng Transl Med2020
33659322Single Cell Volume Measurement Utilizing the Fluorescence Exclusion Method (FXm).Bio Protoc2020
31937754Dynamic organelle distribution initiates actin-based spindle migration in mouse oocytes.Nat Commun2020
31700162Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion.Mod Pathol2020
32010778Single-cell morphology encodes metastatic potential.Sci Adv2020
31943628Supramolecular Design of Unsymmetric Reverse Bolaamphiphiles for Cell-Sensitive Hydrogel Degradation and Drug Release.Angew Chem Int Ed Engl2020
32931737Completing the Great Unfinished Symphony of Cancer Together: The Importance of Immigrants in Cancer Research.Cancer Cell2020
32789173Dorsoventral polarity directs cell responses to migration track geometries.Sci Adv2020
32476131Three-dimensional analysis of extrahepatic cholangiocarcinoma and tumor budding.J Pathol2020
30359779Dissecting cellular mechanics: Implications for aging, cancer, and immunity.Semin Cell Dev Biol2019
30261154Recapitulation of molecular regulators of nuclear motion during cell migration.Cell Adh Migr2019
31174838Solid Stress in Brain Tumors.Trends Cancer2019
31481532YAP and TAZ regulate cell volume.J Cell Biol2019
30872360Enabling migration by moderation: YAP/TAZ are essential for persistent migration.J Cell Biol2019
29097501EB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration.FASEB J2018
29915189A comparison of methods to assess cell mechanical properties.Nat Methods2018
30113884Cell tension and mechanical regulation of cell volume.Mol Biol Cell2018
30110623Pluri-IQ: Quantification of Embryonic Stem Cell Pluripotency through an Image-Based Analysis Software.Stem Cell Reports2018
30220965Tumor cell density regulates matrix metalloproteinases for enhanced migration.Oncotarget2018
30368747Mechanics of the Cell Nucleus.Adv Exp Med Biol2018
30361056Metabolic and Mechanical Cues Regulating Pluripotent Stem Cell Fate.Trends Cell Biol2018
29643476Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway.Oncogene2018
29361533Role of membrane-tension gated Ca<sup>2+</sup> flux in cell mechanosensation.J Cell Sci2018
29743594Multi-nucleated cells use ROS to induce breast cancer chemo-resistance in vitro and in vivo.Oncogene2018
29684363Immunolabeling of Cleared Human Pancreata Provides Insights into Three-Dimensional Pancreatic Anatomy and Pathology.Am J Pathol2018
29535303Author Correction: Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology.Nat Commun2018
28712847Pluri-IQ: Quantification of Embryonic Stem Cell Pluripotency through an Image-Based Analysis Software.Stem Cell Reports2017
31372309Biophysical and biomolecular determination of cellular age in humans.Nat Biomed Eng2017
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Collaborators

Konstantinos Konstantopoulos
Co-authored papers 21
Shyam B Khatau
The Johns Hopkins University
Co-authored papers 16
Jerry S H Lee
University of Southern California
Co-authored papers 16
Peter C Searson
Institute for NanoBioTechnology, Johns Hopkins University
Co-authored papers 7
Stephanie I Fraley
University of California San Diego
Co-authored papers 6
Steven C Almo
Albert Einstein College of Medicine
Co-authored papers 5
Sharon Gerecht
Duke University, Johns Hopkins University
Co-authored papers 3
Robert F Siliciano
Johns Hopkins University School of Medicine
Co-authored papers 3
Rong Fan
Institute of Pathogens and Vectors, Dali University
Co-authored papers 3
Ashani T Weeraratna
Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine
Co-authored papers 3
Bridget Wildt
c Center for Devices and Radiological Health
Co-authored papers 3
Prashant Mali (CM4AI)
University of California San Diego
Co-authored papers 2
Elana J Fertig
Johns Hopkins University School of Medicine
Co-authored papers 2
Kenneth J Pienta
The Brady Urological Institute, Johns Hopkins University School of Medicine
Co-authored papers 2
Elizabeth M Jaffee
Convergence Institute, Johns Hopkins University
Co-authored papers 2
Arrate Mu??oz-Barrutia
Universidad Carlos III de Madrid
Co-authored papers 2
Sravanti Kusuma
Johns Hopkins Physical Sciences, Oncology Center and Institute for NanoBioTechnology
Co-authored papers 2
Jungwoo Wren Kim
Institute for Cell Engineering, Johns Hopkins University School of Medicine
Co-authored papers 1
Zhen Zhang
Co-authored papers 1
Ronny Drapkin
University of Pennsylvania School of Medicine
Co-authored papers 1
Andrew V Kossenkov
The Wistar Institute
Co-authored papers 1
Alexander V Favorov
Johns Hopkins School of Medicine
Co-authored papers 1
Joseph E Aslan
Oregon Health & Science University
Co-authored papers 1
Donny Hanjaya-Putra
University of Notre Dame
Co-authored papers 1
Linzhao Cheng
Johns Hopkins University School of Medicine
Co-authored papers 1
Valerie M Weaver
University of California san francisco
Co-authored papers 1
Kun-Liang Guan
University of California San Diego
Co-authored papers 1
Birgit Schilling
Buck Institute for Research on Aging
Co-authored papers 1
Richard Bonneau
Center for Computational Biology (CCB), Flatiron Institute, Simons Foundation
Co-authored papers 1
Christopher S Poultney
Co-authored papers 1
Release 1.2