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Author Details
Full Name
Tero Aittokallio
Affiliation
Institute for Molecular Medicine Finland (FIMM), University of Helsinki
ORCID
Career Start Year
1999
Papers
244
H Index
52
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37996540
Robust scoring of selective drug responses for patient-tailored therapy selection.
Nat Protoc
2024
36795353
Systematic Literature Review of Economic Evaluations of Treatment Alternatives in Chronic Lymphocytic Leukemia.
BioDrugs
2023
37485377
Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells.
iScience
2023
37458534
PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells.
Mol Oncol
2023
37454231
Resistance to immune checkpoint therapies by tumour-induced T-cell desertification and exclusion: key mechanisms, prognostication and new therapeutic opportunities.
Br J Cancer
2023
37178002
Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data.
Nucleic Acids Res
2023
37173993
The miR-141/200c-STAT4 Axis Contributes to Leukemogenesis by Enhancing Cell Proliferation in T-PLL.
Cancers (Basel)
2023
36476658
Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer: real-time therapy tailoring for a patient with low-grade serous carcinoma.
Br J Cancer
2023
36733367
Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia.
Front Oncol
2023
36897911
OSCAR: Optimal subset cardinality regression using the L0-pseudonorm with applications to prognostic modelling of prostate cancer.
PLoS Comput Biol
2023
34655289
Artificial intelligence for drug response prediction in disease models.
Brief Bioinform
2022
35585485
Evaluation of statistical approaches for association testing in noisy drug screening data.
BMC Bioinformatics
2022
35507270
Computational Pipeline for Rational Drug Combination Screening in Patient-Derived Cells.
Methods Mol Biol
2022
35580060
SynergyFinder 3.0: an interactive analysis and consensus interpretation of multi-drug synergies across multiple samples.
Nucleic Acids Res
2022
35573198
High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated mice.
iScience
2022
35489642
Tumor microenvironment as a metapopulation model: The effects of angiogenesis, emigration and treatment modalities.
J Theor Biol
2022
35685365
Systematic review of computational methods for drug combination prediction.
Comput Struct Biotechnol J
2022
36699400
<i>EnrichIntersect</i>: an R package for custom set enrichment analysis and interactive visualization of intersecting sets.
Bioinform Adv
2022
35998013
Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia.
Clin Cancer Res
2022
35963891
Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells.
Sci Rep
2022
36305426
Discovery of host-directed modulators of virus infection by probing the SARS-CoV-2-host protein-protein interaction network.
Brief Bioinform
2022
35992090
Tissue-specific identification of multi-omics features for pan-cancer drug response prediction.
iScience
2022
36225560
Target-specific compound selectivity for multi-target drug discovery and repurposing.
Front Pharmacol
2022
36190406
Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2.
Microbiol Spectr
2022
35945345
An immunity and pyroptosis gene-pair signature predicts overall survival in acute myeloid leukemia.
Leukemia
2022
35255749
What are the current challenges for machine learning in drug discovery and repurposing?
Expert Opin Drug Discov
2022
35273156
Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data.
Nat Commun
2022
34789538
Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia.
Cancer Discov
2022
32142444
Characterizing the Quality of Insight by Interactions: A Case Study.
IEEE Trans Vis Comput Graph
2021
33543671
Artificial intelligence, machine learning, and drug repurposing in cancer.
Expert Opin Drug Discov
2021
33672199
Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling.
Cancers (Basel)
2021
33750001
Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor.
Mol Syst Biol
2021
33608276
Patient-tailored design for selective co-inhibition of leukemic cell subpopulations.
Sci Adv
2021
33631125
Re-defining synthetic lethality by phenotypic profiling for precision oncology.
Cell Chem Biol
2021
34933447
Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses.
mBio
2021
34661156
Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS.
Blood Cancer Discov
2021
34252952
Modeling drug combination effects via latent tensor reconstruction.
Bioinformatics
2021
34302041
Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia.
NPJ Precis Oncol
2021
34101461
Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia.
J Med Chem
2021
34343245
Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer.
Brief Bioinform
2021
34149812
Multi-Omics Marker Analysis Enables Early Prediction of Breast Tumor Progression.
Front Genet
2021
34006613
Erratum for Herring et al., "Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs".
Antimicrob Agents Chemother
2021
34083538
Crowdsourced mapping of unexplored target space of kinase inhibitors.
Nat Commun
2021
33097839
Corrections: Reinstated p53 response and high anti-T-cell leukemia activity by the novel alkylating deacetylase inhibitor tinostamustine.
Leukemia
2021
33468464
Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs.
Antimicrob Agents Chemother
2021
32782381
RUNX1 mutations in blast-phase chronic myeloid leukemia associate with distinct phenotypes, transcriptional profiles, and drug responses.
Leukemia
2021
30566623
Interactive visual analysis of drug-target interaction networks using Drug Target Profiler, with applications to precision medicine and drug repurposing.
Brief Bioinform
2020
32029551
<i>UBR5</i> Is Coamplified with <i>MYC</i> in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis.
Cancer Res
2020
31783311
Cost-effective survival prediction for patients with advanced prostate cancer using clinical trial and real-world hospital registry datasets.
Int J Med Inform
2020
31866377
Genetic and functional implications of an exonic TRIM55 variant in heart failure.
J Mol Cell Cardiol
2020
1 - 50 of 244
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