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Author Details

Tero Aittokallio
Institute for Molecular Medicine Finland (FIMM), University of Helsinki
1999
244
52
PMIDPaper TitleJournal TitlePublished Year
37996540Robust scoring of selective drug responses for patient-tailored therapy selection.Nat Protoc2024
36795353Systematic Literature Review of Economic Evaluations of Treatment Alternatives in Chronic Lymphocytic Leukemia.BioDrugs2023
37485377Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells.iScience2023
37458534PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells.Mol Oncol2023
37454231Resistance to immune checkpoint therapies by tumour-induced T-cell desertification and exclusion: key mechanisms, prognostication and new therapeutic opportunities.Br J Cancer2023
37178002Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data.Nucleic Acids Res2023
37173993The miR-141/200c-STAT4 Axis Contributes to Leukemogenesis by Enhancing Cell Proliferation in T-PLL.Cancers (Basel)2023
36476658Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer: real-time therapy tailoring for a patient with low-grade serous carcinoma.Br J Cancer2023
36733367Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia.Front Oncol2023
36897911OSCAR: Optimal subset cardinality regression using the L0-pseudonorm with applications to prognostic modelling of prostate cancer.PLoS Comput Biol2023
34655289Artificial intelligence for drug response prediction in disease models.Brief Bioinform2022
35585485Evaluation of statistical approaches for association testing in noisy drug screening data.BMC Bioinformatics2022
35507270Computational Pipeline for Rational Drug Combination Screening in Patient-Derived Cells.Methods Mol Biol2022
35580060SynergyFinder 3.0: an interactive analysis and consensus interpretation of multi-drug synergies across multiple samples.Nucleic Acids Res2022
35573198High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated mice.iScience2022
35489642Tumor microenvironment as a metapopulation model: The effects of angiogenesis, emigration and treatment modalities.J Theor Biol2022
35685365Systematic review of computational methods for drug combination prediction.Comput Struct Biotechnol J2022
36699400<i>EnrichIntersect</i>: an R package for custom set enrichment analysis and interactive visualization of intersecting sets.Bioinform Adv2022
35998013Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia.Clin Cancer Res2022
35963891Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells.Sci Rep2022
36305426Discovery of host-directed modulators of virus infection by probing the SARS-CoV-2-host protein-protein interaction network.Brief Bioinform2022
35992090Tissue-specific identification of multi-omics features for pan-cancer drug response prediction.iScience2022
36225560Target-specific compound selectivity for multi-target drug discovery and repurposing.Front Pharmacol2022
36190406Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2.Microbiol Spectr2022
35945345An immunity and pyroptosis gene-pair signature predicts overall survival in acute myeloid leukemia.Leukemia2022
35255749What are the current challenges for machine learning in drug discovery and repurposing?Expert Opin Drug Discov2022
35273156Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data.Nat Commun2022
34789538Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia.Cancer Discov2022
32142444Characterizing the Quality of Insight by Interactions: A Case Study.IEEE Trans Vis Comput Graph2021
33543671Artificial intelligence, machine learning, and drug repurposing in cancer.Expert Opin Drug Discov2021
33672199Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling.Cancers (Basel)2021
33750001Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor.Mol Syst Biol2021
33608276Patient-tailored design for selective co-inhibition of leukemic cell subpopulations.Sci Adv2021
33631125Re-defining synthetic lethality by phenotypic profiling for precision oncology.Cell Chem Biol2021
34933447Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses.mBio2021
34661156Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS.Blood Cancer Discov2021
34252952Modeling drug combination effects via latent tensor reconstruction.Bioinformatics2021
34302041Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia.NPJ Precis Oncol2021
34101461Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia.J Med Chem2021
34343245Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer.Brief Bioinform2021
34149812Multi-Omics Marker Analysis Enables Early Prediction of Breast Tumor Progression.Front Genet2021
34006613Erratum for Herring et al., "Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs".Antimicrob Agents Chemother2021
34083538Crowdsourced mapping of unexplored target space of kinase inhibitors.Nat Commun2021
33097839Corrections: Reinstated p53 response and high anti-T-cell leukemia activity by the novel alkylating deacetylase inhibitor tinostamustine.Leukemia2021
33468464Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs.Antimicrob Agents Chemother2021
32782381RUNX1 mutations in blast-phase chronic myeloid leukemia associate with distinct phenotypes, transcriptional profiles, and drug responses.Leukemia2021
30566623Interactive visual analysis of drug-target interaction networks using Drug Target Profiler, with applications to precision medicine and drug repurposing.Brief Bioinform2020
32029551<i>UBR5</i> Is Coamplified with <i>MYC</i> in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis.Cancer Res2020
31783311Cost-effective survival prediction for patients with advanced prostate cancer using clinical trial and real-world hospital registry datasets.Int J Med Inform2020
31866377Genetic and functional implications of an exonic TRIM55 variant in heart failure.J Mol Cell Cardiol2020
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Collaborators

University of Copenhagen
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Co-authored papers 25
Karolinska Institute
Co-authored papers 23
University of Turku
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Indian Institute of Technology Kanpur
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Helsinki Institute for Information Technology (HIIT), Aalto University
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Technical Research Centre of Finland
Co-authored papers 10
University of Turku
Co-authored papers 8
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Co-authored papers 7
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Center for Bone and Arthritis Research, University of Gothenburg
Co-authored papers 5
Lund University
Co-authored papers 4
Co-authored papers 4
Bill & Melinda Gates Foundation
Co-authored papers 4
Co-authored papers 3
University of Washington
Co-authored papers 3
Quantitative Biomedical Research Center
Co-authored papers 3
Institute of Computational Biomedicine, Heidelberg University
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Atux Iskay LLC
Co-authored papers 3
University of Texas Southwestern Medical Center
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Center for Bioinformatics, Institut Pasteur CNRS
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SickKids Research Institute
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