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Author Details

Richard W Tsien
New York University Grossman School of Medicine
1968
265
125
PMIDPaper TitleJournal TitlePublished Year
36787750Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity.Neuron2023
37034806Optopharmacological tools for precise spatiotemporal control of oxytocin signaling in the central nervous system and periphery.Res Sq2023
37162922Functional specialization of hippocampal somatostatin-expressing interneurons.bioRxiv2023
36787751Brief synaptic inhibition persistently interrupts firing of fast-spiking interneurons.Neuron2023
34980924Hypothalamic melanin-concentrating hormone regulates hippocampus-dorsolateral septum activity.Nat Neurosci2022
36414006Oxytocin-Modulated Ion Channel Ensemble Controls Depolarization, Integration and Burst Firing in CA2 Pyramidal Neurons.J Neurosci2022
34930847De novo mutations in childhood cases of sudden unexplained death that disrupt intracellular Ca<sup>2+</sup> regulation.Proc Natl Acad Sci U S A2021
33622785Unique dynamics and exocytosis properties of GABAergic synaptic vesicles revealed by three-dimensional single vesicle tracking.Proc Natl Acad Sci U S A2021
32492405Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening.Cell2020
31988403Suspect that modulates the heartbeat is ensnared.Nature2020
33087709Synaptic vesicle traffic is supported by transient actin filaments and regulated by PKA and NO.Nat Commun2020
30606833Weakening synapses to cull memories.Science2019
31092326Real-time three-dimensional tracking of single synaptic vesicles reveals that synaptic vesicles undergoing kiss-and-run fusion remain close to their original fusion site before reuse.Biochem Biophys Res Commun2019
29727670Direct Visualization of Wide Fusion-Fission Pores and Their Highly Varied Dynamics.Cell2018
29934532Calmodulin shuttling mediates cytonuclear signaling to trigger experience-dependent transcription and memory.Nat Commun2018
30293821Oxytocin Transforms Firing Mode of CA2 Hippocampal Neurons.Neuron2018
28874590Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models.Proc Natl Acad Sci U S A2017
26985722Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops.Neuron2016
27734865Roger Yonchien Tsien (1952-2016).Nature2016
27197636What is memory? The present state of the engram.BMC Biol2016
26912895Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression.Science2016
27041500Excitation-Transcription Coupling in Parvalbumin-Positive Interneurons Employs a Novel CaM Kinase-Dependent Pathway Distinct from Excitatory Neurons.Neuron2016
25583246The impact of NMDA receptor hypofunction on GABAergic neurons in the pathophysiology of schizophrenia.Schizophr Res2015
26308981Optogenetics: 10 years after ChR2 in neurons--views from the community.Nat Neurosci2015
26282273Cannabinoids and Epilepsy.Neurotherapeutics2015
25998737Evolutionary and functional perspectives on signaling from neuronal surface to nucleus.Biochem Biophys Res Commun2015
25700840Distinct roles of multiple isoforms of CaMKII in signaling to the nucleus.Biochim Biophys Acta2015
25730884Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis.Proc Natl Acad Sci U S A2015
24908477CaV1.2 calcium channels: just cut out to be regulated?Neuron2014
25303525γCaMKII shuttles Ca²⁺/CaM to the nucleus to trigger CREB phosphorylation and gene expression.Cell2014
25014658Virtual finger boosts three-dimensional imaging and microsurgery as well as terabyte volume image visualization and analysis.Nat Commun2014
24870235Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission.Nature2014
23245563Perspectives on kiss-and-run: role in exocytosis, endocytosis, and neurotransmission.Annu Rev Physiol2013
23913275Oxytocin enhances hippocampal spike transmission by modulating fast-spiking interneurons.Nature2013
24019485Ca2+ channel nanodomains boost local Ca2+ amplitude.Proc Natl Acad Sci U S A2013
24012005GABAergic projection neurons route selective olfactory inputs to specific higher-order neurons.Neuron2013
23974710GluA1 phosphorylation at serine 831 in the lateral amygdala is required for fear renewal.Nat Neurosci2013
23630279AMPA receptor exchange underlies transient memory destabilization on retrieval.Proc Natl Acad Sci U S A2013
22345401Influence of synaptic vesicle position on release probability and exocytotic fusion mode.Science2012
23088728Exploring the dominant role of Cav1 channels in signalling to the nucleus.Biosci Rep2012
22745285Synaptic vesicle pools and dynamics.Cold Spring Harb Perspect Biol2012
22634730pHTomato, a red, genetically encoded indicator that enables multiplex interrogation of synaptic activity.Nat Neurosci2012
22632974Ca(V)1 and Ca(V)2 channels engage distinct modes of Ca(2+) signaling to control CREB-dependent gene expression.Cell2012
22615990An improved test for detecting multiplicative homeostatic synaptic scaling.PLoS One2012
21187407Beta Ca2+/CaM-dependent kinase type II triggers upregulation of GluA1 to coordinate adaptation to synaptic inactivity in hippocampal neurons.Proc Natl Acad Sci U S A2011
22179109Heterogeneous reallocation of presynaptic efficacy in recurrent excitatory circuits adapting to inactivity.Nat Neurosci2011
21878566Mouse model of Timothy syndrome recapitulates triad of autistic traits.Proc Natl Acad Sci U S A2011
21527343Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer.Neurobiol Dis2011
21753754MicroRNA-mediated conversion of human fibroblasts to neurons.Nature2011
21352861Excitation-transcription coupling in sympathetic neurons and the molecular mechanism of its initiation.Neurosci Res2011
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Collaborators

Cardiovascular Research Center, Massachusetts General Hospital
Co-authored papers 9
University of California
Co-authored papers 6
Columbia University
Co-authored papers 5
Neuroscience Institute, Langone Medical Center, New York University
Co-authored papers 5
University of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience
Co-authored papers 4
Co-authored papers 3
New York University Langone Medical Center
Co-authored papers 3
Laval University
Co-authored papers 3
Boston Children's Hospital, United States New York University Langone Medical Center
Co-authored papers 2
Stanford University School of Medicine
Co-authored papers 2
and Pharmacy, University of Reading, UK GW Research Ltd
Co-authored papers 2
Co-authored papers 2
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 2
Mitsubishi Tanabe Pharma America, Inc.
Co-authored papers 2
McGovern Institute for Brain Research
Co-authored papers 2
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
Kavli Institute for Neuroscience, Yale University School of Medicine
Co-authored papers 1
Allen Institute for Brain Science
Co-authored papers 1
Co-authored papers 1
University of New Mexico
Co-authored papers 1
Institute for Systems Genetics, NYU School of Medicine
Co-authored papers 1
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Stanford University
Co-authored papers 1
Aston Neuroscience Institute, Aston University
Co-authored papers 1
The Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Co-authored papers 1
and Pharmacy, University of Reading, UK GW Research Ltd
Co-authored papers 1
Co-authored papers 1
Allen Institute for Brain Science
Co-authored papers 1