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Author Details

Rick K Huang
National Cancer Institute, National Institutes of Health
2007
34
21
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36514310Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD.iScience2023
37236355Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc<sub>1</sub> complexes.J Biol Chem2023
37131729Structure-function Analyses Reveal Key Molecular Determinants of HIV-1 CRF01_AE Resistance to the Entry Inhibitor Temsavir.bioRxiv2023
34971573Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern.Cell Rep2022
33452495Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA.Nat Microbiol2021
34537245Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.J Biol Chem2021
34159326Structures of synthetic nanobody-SARS-CoV-2-RBD complexes reveal distinct sites of interaction and recognition of variants.Res Sq2021
34260280Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment.J Virol2021
34373853Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern.bioRxiv2021
32310951Expression of quasi-equivalence and capsid dimorphism in the Hepadnaviridae.PLoS Comput Biol2020
32665714Author Correction: Structure of human GABA<sub>B</sub> receptor in an inactive state.Nature2020
32581365Structure of human GABA<sub>B</sub> receptor in an inactive state.Nature2020
30542156Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex.Nature2019
31704029Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex.Cell2019
31740855Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex.Nat Struct Mol Biol2019
30630865Cryo-EM of retinoschisin branched networks suggests an intercellular adhesive scaffold in the retina.J Cell Biol2019
29590090Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.Nature2018
29950717Cryo-EM structure of an essential Plasmodium vivax invasion complex.Nature2018
30004384Cryo-EM structure of the polycystin 2-l1 ion channel.Elife2018
28784753Near-atomic resolution cryoelectron microscopy structure of the 30-fold homooligomeric SpoIIIAG channel essential to spore formation in <i>Bacillus subtilis</i>.Proc Natl Acad Sci U S A2017
29146813Structural basis of bacterial transcription activation.Science2017
27114531Paired octamer rings of retinoschisin suggest a junctional model for cell-cell adhesion in the retina.Proc Natl Acad Sci U S A2016
27974800Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body.Nature2016
27265851The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly.Structure2016
24361271Architecture of a dsDNA viral capsid in complex with its maturation protease.Structure2014
26712354Distinguishing direct binding interactions from allosteric effects in the protease-HK97 prohead I δ domain complex by amide H/D exchange mass spectrometry.Bacteriophage2014
24804986Amyloid triangles, squares, and loops of apolipoprotein C-III.Biochemistry2014
24853742Conformational switching in PolyGln amyloid fibrils resulting from a single amino acid insertion.Biophys J2014
24109217A two-pronged structural analysis of retroviral maturation indicates that core formation proceeds by a disassembly-reassembly pathway rather than a displacive transition.J Virol2013
21276801The Prohead-I structure of bacteriophage HK97: implications for scaffold-mediated control of particle assembly and maturation.J Mol Biol2011
21182418Transferrin-mediated targeting of bacteriophage HK97 nanoparticles into tumor cells.Nanomedicine (Lond)2011
20332083Critical salt bridges guide capsid assembly, stability, and maturation behavior in bacteriophage HK97.Mol Cell Proteomics2010
20164221Structure and function of a genetically engineered mimic of a nonenveloped virus entry intermediate.J Virol2010
17502099The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family.Structure2007
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Collaborators

Howard Hughes Medical Institute
Co-authored papers 9
National Institutes of Health
Co-authored papers 6
Frederick National Laboratory for Cancer Research, Inc.
Co-authored papers 4
Co-authored papers 3
Co-authored papers 3
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 2
New York University Grossman School of Medicine
Co-authored papers 2
University of California davis
Co-authored papers 2
Co-authored papers 2
Columbia University
Co-authored papers 2
Columbia University
Co-authored papers 2
Co-authored papers 2
Herbert Irving Comprehensive Cancer Center, Columbia University
Co-authored papers 2
The University of British Columbia
Co-authored papers 2
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
University of Georgia
Co-authored papers 2
Co-authored papers 1
Utrecht University
Co-authored papers 1
The Joint Center for Structural Genomics, Stanford University
Co-authored papers 1
Pfizer Inc.
Co-authored papers 1
Skane University Hospital, Lund University
Co-authored papers 1
Monash University
Co-authored papers 1
National Centre for Cell Science, SP Pune University Campus
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of Washington
Co-authored papers 1
Expres2ion Biotechnologies
Co-authored papers 1
University of Oxford
Co-authored papers 1
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