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Author Details

Luis Enjuanes
Campus Universidad Autonoma de Madrid
1971
249
71
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36602354Atypical Mutational Spectrum of SARS-CoV-2 Replicating in the Presence of Ribavirin.Antimicrob Agents Chemother2023
37623322SARS-CoV-2 ORF8 accessory protein is a virulence factor.mBio2023
37947413Correction for Castaño-Rodriguez et al., "Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis".mBio2023
37942479Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis.Front Cell Infect Microbiol2023
37607224SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice.Proc Natl Acad Sci U S A2023
36992394Efficient CRISPR-Cas13d-Based Antiviral Strategy to Combat SARS-CoV-2.Viruses2023
37206325Dextran sulfate from <i>Leuconostoc mesenteroides</i> B512F exerts potent antiviral activity against SARS-CoV-2 <i>in vitro</i> and <i>in vivo</i>.Front Microbiol2023
37066301SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice.bioRxiv2023
37197199Contribution to pathogenesis of accessory proteins of deadly human coronaviruses.Front Cell Infect Microbiol2023
36625656SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators.mBio2023
36854765Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinase.Nat Commun2023
34817201Reverse Genetics with a Full-Length Infectious cDNA Clone of Bovine Torovirus.J Virol2022
35348367SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes.Microbiol Spectr2022
35471062An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern.Sci Immunol2022
35745516SARS-CoV-2 Mutant Spectra at Different Depth Levels Reveal an Overwhelming Abundance of Low Frequency Mutations.Pathogens2022
35966177Nature of viruses and pandemics: Coronaviruses.Curr Res Immunol2022
36360660Pulsed-Xenon Ultraviolet Light Highly Inactivates Human Coronaviruses on Solid Surfaces, Particularly SARS-CoV-2.Int J Environ Res Public Health2022
36129908MERS-CoV ORF4b is a virulence factor involved in the inflammatory pathology induced in the lungs of mice.PLoS Pathog2022
36224622Detection of SARS-CoV-2 in a dog with hemorrhagic diarrhea.BMC Vet Res2022
35012962Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.Life Sci Alliance2022
35314834Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19.Nature2022
34851142Development of a Single-Cycle Infectious SARS-CoV-2 Virus Replicon Particle System for Use in Biosafety Level 2 Laboratories.J Virol2022
35229638Contribution of Host miRNA-223-3p to SARS-CoV-Induced Lung Inflammatory Pathology.mBio2022
35323099Suitability of transiently expressed antibodies for clinical studies: product quality consistency at different production scales.MAbs2022
33144319Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice.J Virol2021
33653888Genetically Engineered Live-Attenuated Middle East Respiratory Syndrome Coronavirus Viruses Confer Full Protection against Lethal Infection.mBio2021
33731724A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies.Nat Commun2021
33929101A multiplex antigen microarray for simultaneous IgG and IgM detection against SARS-CoV-2 reveals higher seroprevalence than reported.Microb Biotechnol2021
34517762MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity.mBio2021
34686605Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice.Proc Natl Acad Sci U S A2021
34075384Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.medRxiv2021
34014525Viral PDZ Binding Motifs Influence Cell Behavior Through the Interaction with Cellular Proteins Containing PDZ Domains.Methods Mol Biol2021
34237296Science, not speculation, is essential to determine how SARS-CoV-2 reached humans.Lancet2021
32900263Cross-neutralization activity against SARS-CoV-2 is present in currently available intravenous immunoglobulins.Immunotherapy2020
32087122Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19.Lancet2020
30938227Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein.Emerg Microbes Infect2019
31861369Minimum Determinants of Transmissible Gastroenteritis Virus Enteric Tropism Are Located in the N-Terminus of Spike Protein.Pathogens2019
31349683Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV) - Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDV.Viruses2019
31034780Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC.FASEB J2019
29370303MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.PLoS Pathog2018
30101189Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection.Sci Adv2018
30200258S1 Subunit of Spike Protein from a Current Highly Virulent Porcine Epidemic Diarrhea Virus Is an Important Determinant of Virulence in Piglets.Viruses2018
30110630Adaptive Evolution of MERS-CoV to Species Variation in DPP4.Cell Rep2018
29789363Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis.mBio2018
28931424Erratum to: Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus.Vet Res2017
28216251SARS-CoV-Encoded Small RNAs Contribute to Infection-Associated Lung Pathology.Cell Host Microbe2017
28393915Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.Sci Rep2017
28797297Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus.Vet Res2017
27009949Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.J Virol2016
28641298Generation of a DNA-Launched Reporter Replicon Based on Dengue Virus Type 2 as a Multipurpose Platform.Intervirology2016
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Collaborators

Campus Universidad Autonoma de Madrid
Co-authored papers 86
Campus Universidad Autonoma de Madrid
Co-authored papers 47
Erasmus Medical Center
Co-authored papers 7
Leiden University Medical Center
Co-authored papers 5
University of North Carolina
Co-authored papers 4
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Hospital Universitario Marques de Valdecilla
Co-authored papers 2
Departamento de Toxicologia y Farmacologia Preclinica
Co-authored papers 2
Clinical Development
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 2
Hospital Universitario HM Monteprincipe, HM Hospitales
Co-authored papers 2
Clinical Development
Co-authored papers 2
University of Geneva
Co-authored papers 2
Instituto de Salud Carlos III, Hospital Universitario La Princesa
Co-authored papers 2
Hospital Germans Trias i Pujol
Co-authored papers 2
Hospital Universitario Quironsalud Madrid
Co-authored papers 2
Hospital Universitario Ramon y Cajal
Co-authored papers 2
Institute of Medical Virology Justus Liebig University
Co-authored papers 2
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
Hospital Universitario de Getafe
Co-authored papers 2
Co-authored papers 2
Hospital Universitario de La Princesa
Co-authored papers 2
Universidad Europea
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
University College London
Co-authored papers 2
Clinical R&D
Co-authored papers 2
IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 2
Hospital Universitario de Getafe
Co-authored papers 2