Author details

Full Name

Marilyn J Telen

Affiliation

ORCID

Career Start Year

1983

Papers

180

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37533140	Differences in the Circulating Proteome in Individuals with versus without Sickle Cell Trait.	Clin J Am Soc Nephrol	2023
36226494	Variation and impact of polygenic hematologic traits in monogenic sickle cell disease.	Haematologica	2023
35981565	A randomized clinical trial of the efficacy and safety of rivipansel for sickle cell vaso-occlusive crisis.	Blood	2023
36399516	Genome-wide meta-analysis identifies new candidate genes for sickle cell disease nephropathy.	Blood Adv	2023
38033286	Deciphering and Disrupting PIEZO1-TMEM16F Interplay in Hereditary Xerocytosis.		2023
37662265	WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.	medRxiv	2023
37905989	Preferences for potential benefits and risks for gene therapy in the treatment of sickle cell disease.		2023
38077122	Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results.		2023
36778386	Structural variation across 138,134 samples in the TOPMed consortium.	Res Sq	2023
36702996	Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.	Nat Genet	2023
36747810	Structural variation across 138,134 samples in the TOPMed consortium.	bioRxiv	2023
36546431	Sex differences in progression of kidney disease in sickle cell disease.	Haematologica	2023
36993312	Genetic regulation of fetal hemoglobin across global populations.	medRxiv	2023
36993181	Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results.		2023
36853587	Management of Older Adults with Sickle Cell Disease: Considerations for Current and Emerging Therapies.		2023
34990411	Clonal hematopoiesis in sickle cell disease.	J Clin Invest	2022
36296435	Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease.	Molecules	2022
35696734	Longitudinal study of glomerular hyperfiltration in adults with sickle cell anemia: a multicenter pooled analysis.	Blood Adv	2022
35927319	Rare genetic variants explain missing heritability in smoking.	Nat Hum Behav	2022
36400533	Genetic Modifiers of Sickle Cell Disease.	Hematology/Oncology Clinics of North America	2022
36477530	Genetic diversity fuels gene discovery for tobacco and alcohol use.	Nature	2022
34615515	Identification of optimal thalassemia screening strategies for migrant populations in Thailand using a qualitative approach.	BMC Public Health	2021
34154562	Feasibility of and barriers to thalassemia screening in migrant populations: a cross-sectional study of Myanmar and Cambodian migrants in Thailand.	BMC Public Health	2021
33179474	Rapid decline in estimated glomerular filtration rate in sickle cell anemia: results of a multicenter pooled analysis.	Haematologica	2021
33231305	Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program.	Transfusion	2021
32949984	Potential causal role of l-glutamine in sickle cell disease painful crises: A Mendelian randomization analysis.	Blood Cells Mol Dis	2021
32722787	Curative vs targeted therapy for SCD: does it make more sense to address the root cause than target downstream events?	Blood advances	2020
33339817	Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.	Nat Commun	2020
33054072	Pyridoxamine: another vitamin for sickle cell disease?	Haematologica	2020
32776978	Serum albumin is independently associated with higher mortality in adult sickle cell patients: Results of three independent cohorts.	PLoS One	2020
30663090	A multi-institutional comparison of younger and older adults with sickle cell disease.	American Journal of Hematology	2019
30514970	Therapeutic strategies for sickle cell disease: towards a multi-agent approach.	Nature Reviews Drug Discovery	2019
31484636	Nitric oxide loading reduces sickle red cell adhesion and vaso-occlusion in vivo.	Blood Adv	2019
31158233	RNA sequencing of isolated cell populations expressing human APOL1 G2 risk variant reveals molecular correlates of sickle cell nephropathy in zebrafish podocytes.	PLoS ONE	2019
30144150	Clinical and metabolomic risk factors associated with rapid renal function decline in sickle cell disease.	Am J Hematol	2018
30105803	A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients.	American Journal of Hematology	2018
28033687	Thrombospondin-1 gene polymorphism is associated with estimated pulmonary artery pressure in patients with sickle cell anemia.	Am J Hematol	2017
28484512	Developing new pharmacotherapeutic approaches to treating sickle-cell disease.		2017
29296845	Depression, quality of life, and medical resource utilization in sickle cell disease.	Blood advances	2017
27549988	Sevuparin binds to multiple adhesive ligands and reduces sickle red blood cell-induced vaso-occlusion.	British Journal of Haematology	2016
26758919	Beyond hydroxyurea: new and old drugs in the pipeline for sickle cell disease.	Blood	2016
27071063	Phase 1 Study of a Sulforaphane-Containing Broccoli Sprout Homogenate for Sickle Cell Disease.	PLoS ONE	2016
27508053	Biomarkers and recent advances in the management and therapy of sickle cell disease.	F1000Research	2015
25444611	Alloimmunization in sickle cell disease: changing antibody specificities and association with chronic pain and decreased survival.	Transfusion	2015
25733584	Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use.	Blood	2015
26379250	Correction: In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress.	PLoS Genet	2015
26377572	Validation of a novel point of care testing device for sickle cell disease.	BMC Medicine	2015
26573221	A comprehensive joint analysis of the long and short RNA transcriptomes of human erythrocytes.	BMC Genomics	2015
26147622	In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress.	PLoS Genet	2015
25125721	Teaching evidence-based medicine in the former Soviet Union: lessons learned.	Transactions of the American Clinical and Climatological Association	2014