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Author Details
Full Name
Oscar M Tirado
Affiliation
Institut d'Investigacio Biomedica de Bellvitge (IDIBELL)/CIBERONC
ORCID
Career Start Year
2000
Papers
66
H Index
30
Expertise
CM4AI Collaborator
Nathan Sheffield (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36603685
Low Bcl-2 is a robust biomarker of sensitivity to nab-paclitaxel in Ewing sarcoma.
Biochem Pharmacol
2023
37251690
Combination of protein and cell internalization SELEX identifies a potential RNA therapeutic and delivery platform to treat EphA2-expressing tumors.
Mol Ther Nucleic Acids
2023
34974029
SPARC-mediated long-term retention of nab-paclitaxel in pediatric sarcomas.
J Control Release
2022
35712255
Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage Response.
Front Endocrinol (Lausanne)
2022
35354905
Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1.
Oncogene
2022
33479225
Sarcoma classification by DNA methylation profiling.
Nat Commun
2021
33982741
Harnessing subcellular-resolved organ distribution of cationic copolymer-functionalized fluorescent nanodiamonds for optimal delivery of active siRNA to a xenografted tumor in mice.
Nanoscale
2021
33326104
Metastasis Assessment in Ewing Sarcoma Using Orthotopic Xenografts.
Methods Mol Biol
2021
33097530
RING1B recruits EWSR1-FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis.
Sci Adv
2020
31963599
Exosomes in Bone Sarcomas: Key Players in Metastasis.
Cells
2020
31911079
LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity.
Cancer Lett
2020
30846724
Bcl-x<sub>L</sub> inhibition enhances Dinaciclib-induced cell death in soft-tissue sarcomas.
Sci Rep
2019
31484926
The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition.
Nat Commun
2019
31167577
Targeting fusion proteins: a double edge sword?
Expert Opin Ther Targets
2019
29177953
Phase II Study of Gemcitabine Plus Sirolimus in Previously Treated Patients with Advanced Soft-Tissue Sarcoma: a Spanish Group for Research on Sarcomas (GEIS) Study.
Target Oncol
2018
29881993
Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.
Acta Neuropathol
2018
30094618
Correction to: DNA methylation-based reclassification of olfactory neuroblastoma.
Acta Neuropathol
2018
30140378
The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma.
Oncotarget
2018
29730775
DNA methylation-based reclassification of olfactory neuroblastoma.
Acta Neuropathol
2018
29582409
EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma.
Int J Cancer
2018
27894957
DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.
Cancer Lett
2017
28672777
Correction: The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin.
Oncotarget
2017
28881358
Ligand-dependent Hedgehog pathway activation in Rhabdomyosarcoma: the oncogenic role of the ligands.
Br J Cancer
2017
28832268
DNA methylation profiling opens a new phase in the search of targeted therapy against Ewing sarcoma.
Pharmacogenomics
2017
26802024
The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.
Oncotarget
2016
26563256
Clinical practice guidelines for the diagnosis and treatment of patients with soft tissue sarcoma by the Spanish group for research in sarcomas (GEIS).
Cancer Chemother Pharmacol
2016
27317769
RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein.
Oncotarget
2016
27315524
The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report.
Clin Sarcoma Res
2016
27487136
Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathway.
Oncotarget
2016
25586480
Sirolimus plus gemcitabine: a new therapeutic combination for resistant sarcomas?
Expert Rev Anticancer Ther
2015
26286475
Cell Death Identification in Anticancer Therapy-Response.
Cancer Res
2015
26056084
The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin.
Oncotarget
2015
25905041
The importance of being dead: cell death mechanisms assessment in anti-sarcoma therapy.
Front Oncol
2015
25724677
"(Not) all (dead) things share the same breath": identification of cell death mechanisms in anticancer therapy.
Cancer Res
2015
25804122
Desmoplastic small round cell tumor 20 years after its discovery.
Future Oncol
2015
23801301
Phase I trial of sorafenib in combination with ifosfamide in patients with advanced sarcoma: a Spanish group for research on sarcomas (GEIS) study.
Invest New Drugs
2014
25281719
Suppression of deacetylase SIRT1 mediates tumor-suppressive NOTCH response and offers a novel treatment option in metastatic Ewing sarcoma.
Cancer Res
2014
25313138
Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth.
Oncotarget
2014
25003665
Phase I study and preclinical efficacy evaluation of the mTOR inhibitor sirolimus plus gemcitabine in patients with advanced solid tumours.
Br J Cancer
2014
23951165
EphA2-induced angiogenesis in ewing sarcoma cells works through bFGF production and is dependent on caveolin-1.
PLoS One
2013
23857410
The dual inhibitory effect of thiostrepton on FoxM1 and EWS/FLI1 provides a novel therapeutic option for Ewing's sarcoma.
Int J Oncol
2013
22701332
Targeted therapies in sarcomas: challenging the challenge.
Sarcoma
2012
21471610
Caveolin-1 in sarcomas: friend or foe?
Oncotarget
2011
21911456
2-deoxyglucose induces Noxa-dependent apoptosis in alveolar rhabdomyosarcoma.
Cancer Res
2011
21373757
Auto-stimulatory action of secreted caveolin-1 on the proliferation of Ewing's sarcoma cells.
Int J Oncol
2011
19609943
Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing's sarcoma cells by modulating PKCalpha phosphorylation.
Int J Cancer
2010
21106507
Caveolin-1 modulates the ability of Ewing's sarcoma to metastasize.
Mol Cancer Res
2010
19128055
Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.
J Med Chem
2009
19117992
PCPH/ENTPD5 expression confers to prostate cancer cells resistance against cisplatin-induced apoptosis through protein kinase Calpha-mediated Bcl-2 stabilization.
Cancer Res
2009
17804748
Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases.
Cancer Res
2007
1 - 50 of 66
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Elizabeth R Lawlor
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