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Author Details

David A Stein
College of Veterinary Medicine, Oregon State University
1990
78
40
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36197970Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans.Sci Adv2022
33164048Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers.J Antimicrob Chemother2021
34556855Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy.Nat Microbiol2021
34319155Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells.J Virol2021
32703818TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells.Life Sci Alliance2020
33024974Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers.bioRxiv2020
31391268TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes.J Virol2019
29375654Human papillomavirus genotype distribution in cervical cancer biopsies from Nepalese women.Infect Agent Cancer2018
29970132Profile of the 2016 dengue outbreak in Nepal.BMC Res Notes2018
30181255Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments.mBio2018
29487874Epidemiological Profile and Risk Factors for Acquiring HBV and/or HCV in HIV-Infected Population Groups in Nepal.Biomed Res Int2018
28248290Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.Nat Microbiol2017
26695437Integrated safety of levodopa-carbidopa intestinal gel from prospective clinical trials.Mov Disord2016
26086884Inhibition of hepatitis E virus replication by peptide-conjugated morpholino oligomers.Antiviral Res2015
26651948Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.Cell Host Microbe2015
24599995Inhibition of dengue virus replication by a class of small-molecule compounds that antagonize dopamine receptor d4 and downstream mitogen-activated protein kinase signaling.J Virol2014
24882218Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.Immunity2014
23824813Flaviviruses are sensitive to inhibition of thymidine synthesis pathways.J Virol2013
21123387Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.J Virol2011
21825302Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors.Antimicrob Agents Chemother2011
21795337Inhibition of dengue virus infections in cell cultures and in AG129 mice by a small interfering RNA targeting a highly conserved sequence.J Virol2011
21554902Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer.Antiviral Res2011
20299495Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-conjugated morpholino oligomer.J Antimicrob Chemother2010
21149921Reduction of herpes simplex virus type-2 replication in cell cultures and in rodent models with peptide-conjugated morpholino oligomers.Antivir Ther2010
20973722High-content assay to identify inhibitors of dengue virus infection.Assay Drug Dev Technol2010
20554776Coxsackievirus B3 infection activates the unfolded protein response and induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1.J Virol2010
20206215Curing of HeLa cells persistently infected with equine arteritis virus by a peptide-conjugated morpholino oligomer.Virus Res2010
19059443Inhibition of measles virus infections in cell cultures by peptide-conjugated morpholino oligomers.Virus Res2009
19918094Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death.Antivir Ther2009
19665486Inhibition of HSV-1 ocular infection with morpholino oligomers targeting ICP0 and ICP27.Antiviral Res2009
19109397Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity.J Virol2009
18037527Cell penetrating peptide conjugates of steric block oligonucleotides.Adv Drug Deliv Rev2008
18842280Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings.Virology2008
18991679Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers.Curr Pharm Des2008
18468653Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers.Virology2008
18567576Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus.J Antimicrob Chemother2008
18258275West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions.Virology2008
18347156Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus.Mol Cancer Ther2008
18347107A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus.Antimicrob Agents Chemother2008
18343835Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus.J Gen Virol2008
18369525Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers.Arch Virol2008
18443602Inhibition of respiratory syncytial virus infections with morpholino oligomers in cell cultures and in mice.Mol Ther2008
17959259Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication.Antiviral Res2008
17981637Nucleic acid-based inhibition of flavivirus infections.Front Biosci2008
16842866Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers.Antiviral Res2007
17635157Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo.Biochem Soc Trans2007
17728223Inhibition of foot-and-mouth disease virus infections in cell cultures with antisense morpholino oligomers.J Virol2007
17344287Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models.J Virol2007
17485503In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virus.Antimicrob Agents Chemother2007
16214197Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure.Virology2006
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Collaborators

Hong M Moulton
Carlson College of Veterinary Medicine, Oregon State University
Co-authored papers 23
Adolfo Garc??a-Sastre
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Pei-Yong Shi
University of Texas Medical Branch
Co-authored papers 5
Jessica L Smith
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 4
Sumit K Chanda
The Scripps Research Institute
Co-authored papers 4
Hans-Dieter Klenk
Institute of Virology, Philipps University
Co-authored papers 4
Alec J Hirsch
Vaccine & Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 4
Shashank Tripathi
Indian Institute of Science
Co-authored papers 4
Jay A Nelson
Oregon Health and Science University
Co-authored papers 4
Ariel Rodriguez-Frandsen
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 4
Paul D De Jesus
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
Lars Pache
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
Guojun Wang
College of Life Sciences, Inner Mongolia University
Co-authored papers 3
Bhavneet Bhinder
Memorial Sloan Kettering Cancer Center, USA Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 3
Randy A Albrecht
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Yingyao Zhou
Genomics Institute of the Novartis Research Foundation
Co-authored papers 2
Quy Nguyen
University of California irvine
Co-authored papers 2
Stephen Soonthornvacharin
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Megan L Shaw
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Sina Bavari
Co-authored papers 2
Elke Mühlberger
Co-authored papers 2
Laura Martin-Sancho
The Scripps Research Institute
Co-authored papers 2
Peter Kuhn
University of Tubingen
Co-authored papers 2
Renate K??nig
Paul-Ehrlich-Institut
Co-authored papers 2
Thong T Nguyen
Gladstone Institute of Virology
Co-authored papers 1
Michael R Emmert-Buck
The Francis Crick Institute
Co-authored papers 1
Alexander Karlas
Max Planck Institute for Infection Biology
Co-authored papers 1
Elisa de Castro
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
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Release 1.2