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Author Details

Peter Horak
German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT)
2003
74
27
PMIDPaper TitleJournal TitlePublished Year
36373660CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase.Nucleic Acids Res2023
37544709Tumour mutational burden and survival with molecularly matched therapy.Eur J Cancer2023
37280276The German Network for Personalized Medicine to enhance patient care and translational research.Nat Med2023
36888935National Center for Tumor Diseases Precision Oncology Thesaurus for Drugs: A Curated Database for Drugs, Drug Classes, and Drug Targets in Precision Cancer Medicine.JCO Clin Cancer Inform2023
36470093Comprehensive molecular profiling of sarcomas in adolescent and young adult patients: Results of the EORTC SPECTA-AYA international proof-of-concept study.Eur J Cancer2023
34331337Assigning evidence to actionability: An introduction to variant interpretation in precision cancer medicine.Genes Chromosomes Cancer2022
35763870Gene expression-based prediction of pazopanib efficacy in sarcoma.Eur J Cancer2022
35366909Correction to: Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations.J Transl Med2022
35624339A community approach to the cancer-variant-interpretation bottleneck.Nat Cancer2022
35563565Recurrent Germline Variant in <i>RAD21</i> Predisposes Children to Lymphoblastic Leukemia or Lymphoma.Int J Mol Sci2022
36428811Current Developments in Cellular Therapy for Castration Resistant Prostate Cancer: A Systematic Review of Clinical Studies.Cancers (Basel)2022
36274133Feasibility and outcome of reproducible clinical interpretation of high-dimensional molecular data: a comparison of two molecular tumor boards.BMC Med2022
36063163Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
35983950Bcl-x<sub>L</sub> as prognostic marker and potential therapeutic target in cholangiocarcinoma.Liver Int2022
35918329Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity.Nat Commun2022
35159020MALAT1 Fusions and Basal Cells Contribute to Primary Resistance against Androgen Receptor Inhibition in TRAMP Mice.Cancers (Basel)2022
35101336Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
32949162Integrating proteomics into precision oncology.Int J Cancer2021
33737722PD-1 and PD-L1 expression on TILs in peritoneal metastases compared to ovarian tumor tissues and its associations with clinical outcome.Sci Rep2021
33667718Targeting rare and non-canonical driver variants in NSCLC - An uncharted clinical field.Lung Cancer2021
34785797Publisher Correction: Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia.Leukemia2021
34808524Rationale and design of the CRAFT (Continuous ReAssessment with Flexible ExTension in Rare Malignancies) multicenter phase II trial.ESMO Open2021
34185311High tumour mutational burden and EGFR/MAPK pathway activation are therapeutic targets in metastatic porocarcinoma.Br J Dermatol2021
33938987[Variant interpretation in molecular pathology and oncology : An introduction].Pathologe2021
34036222CATCH: A Prospective Precision Oncology Trial in Metastatic Breast Cancer.JCO Precis Oncol2021
33980253Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations.J Transl Med2021
34112699Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers.Cancer Discov2021
33479225Sarcoma classification by DNA methylation profiling.Nat Commun2021
31558800Identification and characterization of a BRAF fusion oncoprotein with retained autoinhibitory domains.Oncogene2020
35846099Ruxolitinib is effective in the treatment of a patient with refractory T-ALL.EJHaem2020
32843432Successful BRAF/MEK inhibition in a patient with <i>BRAF</i><sup>V600E</sup>-mutated extrapancreatic acinar cell carcinoma.Cold Spring Harb Mol Case Stud2020
32813113Patient expectations are better for immunotherapy than traditional chemotherapy for cancer.J Cancer Res Clin Oncol2020
32501622Germline SDHB-inactivating mutation in gastric spindle cell sarcoma.Genes Chromosomes Cancer2020
32385320The landscape of chromothripsis across adult cancer types.Nat Commun2020
32127638Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia.Leukemia2020
32156527Metastatic adult pancreatoblastoma: Multimodal treatment and molecular characterization of a very rare disease.Pancreatology2020
30967556Defective homologous recombination DNA repair as therapeutic target in advanced chordoma.Nat Commun2019
31798980Community-driven development of a modified progression-free survival ratio for precision oncology.ESMO Open2019
31438064Finding Options Beyond Standard of Care in Oncology: A Proposal for Workflows Utilizing Knowledge Databases.Stud Health Technol Inform2019
31308077KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy.Mol Cancer Ther2019
30833416Response to olaparib in a <i>PALB2</i> germline mutated prostate cancer and genetic events associated with resistance.Cold Spring Harb Mol Case Stud2019
31008532Variant classification in precision oncology.Int J Cancer2019
28929175TUSC3: functional duality of a cancer gene.Cell Mol Life Sci2018
35135162Validating Comprehensive Next-Generation Sequencing Results for Precision Oncology: The NCT/DKTK Molecularly Aided Stratification for Tumor Eradication Research Experience.JCO Precis Oncol2018
29802158<i>NRG1</i> Fusions in <i>KRAS</i> Wild-Type Pancreatic Cancer.Cancer Discov2018
30555636Synthetic lethal combinations of low-toxicity drugs for breast cancer identified <i>in silico</i> by genetic screens in yeast.Oncotarget2018
28875369[Personalized oncology].Radiologe2017
29030332Genomics of Immunotherapy-Associated Hyperprogressors-Letter.Clin Cancer Res2017
28597939Precision oncology based on omics data: The NCT Heidelberg experience.Int J Cancer2017
26976242Pretransplantation Supportive and Palliative Care Consultation for High-Risk Hematopoietic Cell Transplantation Patients.Biol Blood Marrow Transplant2016
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Collaborators

Stefan Fr??hling
German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT)
Co-authored papers 39
Albrecht Stenzinger
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 35
Benedikt Brors
German Cancer Research Center (DKFZ)
Co-authored papers 26
Barbara Hutter
National Center for Tumor Diseases (NCT) Heidelberg
Co-authored papers 22
Sebastian Uhrig
National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ)
Co-authored papers 20
Simon Kreutzfeldt
German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT)
Co-authored papers 20
Peter Schirmacher
Institute of Pathology, University Hospital Heidelberg
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Daniel H??bschmann
Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM)
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Christof von Kalle
Berlin Institute of Health at Charite-Universitatsmedizin Berlin
Co-authored papers 10
Volker Endris
Institute of Pathology, University Hospital Heidelberg
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Damian T Rieke
German Cancer Consortium and German Cancer Research Center
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Olaf Neumann
Institute of Pathology, University Hospital Heidelberg
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Jan Budczies
Institute of Pathology, University Hospital Heidelberg
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Frederick Klauschen
Institute of Pathology, Ludwig-Maximilians-Universitat Munchen
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Stephan Wolf
Co-authored papers 6
Michael Allg??uer
Institute of Pathology, Heidelberg University Hospital
Co-authored papers 6
Anna-Lena Volckmar
Institut fur Pathologie, Universitatsklinikum Heidelberg
Co-authored papers 5
Martina Kirchner
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 5
Daniel Kazdal
Institut fur Pathologie, Universitatsklinikum Heidelberg
Co-authored papers 4
Gordana Raca
Children's Hospital Los Angeles
Co-authored papers 4
Shruti Rao
Innovation Center for Biomedical Informatics, Georgetown University Medical Center
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Kilannin Krysiak
Washington University School of Medicine
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Rashmi Kanagal-Shamanna
The University of Texas MD Anderson Cancer Center
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Nikolas von Bubnoff
University Hospital of Schleswig-Holstein
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Deborah I Ritter
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Malachi Griffith
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Release 1.2