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Author Details

Martin J Walsh
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
1987
94
43
PMIDPaper TitleJournal TitlePublished Year
36194688Single-Cell RNA Sequencing Reveals New Basic and Translational Insights in the Cystic Fibrosis Lung.Am J Respir Cell Mol Biol2023
37584609Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity.Am J Physiol Endocrinol Metab2023
37503028A single nuclei atlas of aging human abdominal subcutaneous white adipose tissue.Res Sq2023
37022786Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells.JCI Insight2023
37311463Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.Mol Cell2023
37435531Dysfunction of ubiquitin protein ligase <i>MYCBP2</i> leads to cell resilience in human breast cancers.NAR Cancer2023
36853719Isolation of nuclei from frozen human subcutaneous adipose tissue for full-length single-nuclei transcriptional profiling.STAR Protoc2023
36719036BRD4-PRC2 represses transcription of T-helper 2-specific negative regulators during T-cell differentiation.EMBO J2023
36711881The mitochondrial multi-omic response to exercise training across tissues.bioRxiv2023
36637997Multi-omics-based analysis of high grade serous ovarian cancer subtypes reveals distinct molecular processes linked to patient prognosis.FEBS Open Bio2023
36764492TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype.Gastroenterology2023
36865220Structural Analysis of Genomic and Proteomic Signatures Reveal Dynamic Expression of Intrinsically Disordered Regions in Breast Cancer and Tissue.bioRxiv2023
36824282Pseudo-temporal dynamics of chemoresistant triple negative breast cancer cells reveal EGFR/HER2 inhibition as synthetic lethal during mid-neoadjuvant chemotherapy.iScience2023
35992069Single cell full-length transcriptome of human subcutaneous adipose tissue reveals unique and heterogeneous cell populations.iScience2022
35842613LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer.Mol Cancer2022
36469692Selective Inhibitors of Autophagy Reveal New Link between the Cell Cycle and Autophagy and Lead to Discovery of Novel Synergistic Drug Combinations.ACS Chem Biol2022
33741908CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer.Nat Commun2021
31463974Multiscale network analysis reveals molecular mechanisms and key regulators of the tumor microenvironment in gastric cancer.Int J Cancer2020
32587527Sedentary and Trained Older Men Have Distinct Circulating Exosomal microRNA Profiles at Baseline and in Response to Acute Exercise.Front Physiol2020
31289132LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor-Suppressor Gene FGGY.Cancer Res2019
30275445Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma.Nat Commun2018
30012592Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.Proc Natl Acad Sci U S A2018
30061115High resolution annotation of zebrafish transcriptome using long-read sequencing.Genome Res2018
28683341The N<sup>6</sup>-Methyladenosine RNA modification in pluripotency and reprogramming.Curr Opin Genet Dev2017
28412746Krüppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions.Oncotarget2017
28434940Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR<sup>+</sup> Populations with Stem Cell Properties.Stem Cell Reports2017
28265070BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice.Proc Natl Acad Sci U S A2017
28262505Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.Mol Cell2017
28977470The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.Nucleic Acids Res2017
28579396THAP1: Role in Mouse Embryonic Stem Cell Survival and Differentiation.Stem Cell Reports2017
26220772Long Non-coding RNA ANRIL and Polycomb in Human Cancers and Cardiovascular Disease.Curr Top Microbiol Immunol2016
28977995Distinct distributions of genomic features of the 5' and 3' partners of coding somatic cancer gene fusions: arising mechanisms and functional implications.Oncotarget2016
27690302Identification of novel prognostic indicators for triple-negative breast cancer patients through integrative analysis of cancer genomics data and protein interactome data.Oncotarget2016
27559151A network medicine approach to build a comprehensive atlas for the prognosis of human cancer.Brief Bioinform2016
27326334Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7.ACS Med Chem Lett2016
27526323Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer.Nat Genet2016
27520449RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells.Cancer Res2016
27519282ZNF217/ZFP217 Meets Chromatin and RNA.Trends Biochem Sci2016
26774474Deposition of 5-Methylcytosine on Enhancer RNAs Enables the Coactivator Function of PGC-1α.Cell Rep2016
26851214UHRF1 regulation of Dnmt1 is required for pre-gastrula zebrafish development.Dev Biol2016
25553891Structure activity relationships of human galactokinase inhibitors.Bioorg Med Chem Lett2015
26526723Coordination of m(6)A mRNA Methylation and Gene Transcription by ZFP217 Regulates Pluripotency and Reprogramming.Cell Stem Cell2015
25660273Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.Chem Biol2015
25631877CHD6 regulates the topological arrangement of the CFTR locus.Hum Mol Genet2015
24469833High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.Proc Natl Acad Sci U S A2014
24453336E2F1 coregulates cell cycle genes and chromatin components during the transition of oligodendrocyte progenitors from proliferation to differentiation.J Neurosci2014
23085750GSK3β phosphorylation of the KLF6 tumor suppressor promotes its transactivation of p21.Oncogene2013
24900769Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase.ACS Med Chem Lett2013
23455154Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation.EMBO J2013
23536305Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers.Proc Natl Acad Sci U S A2013
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Collaborators

SiDe Li
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 26
Yifei Sun
Icahn School of Medicine at Mount Sinai
Co-authored papers 15
Weijia Zhang
Co-authored papers 13
Francesca Aguilo
Co-authored papers 12
Matthew B Boxer
Co-authored papers 8
Min Shen
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 6
Craig J Thomas
Center for Cancer Research, National Cancer Institute
Co-authored papers 6
Goutham Narla
The University of Michigan Medical School ann arbor
Co-authored papers 5
Bin Zhang
Graduate School of Medicine, The University of Tokyo
Co-authored papers 4
James A Wohlschlegel
David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 4
Ajay A Vashisht
David Geffen School of Medicine, University of California los angeles
Co-authored papers 4
Elena Zaslavsky
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Huabao Xiong
Co-authored papers 2
Musaddeque Ahmed
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Felix Y Feng
UCSF Medical Center-Mount Zion
Co-authored papers 2
Eric A Sobie
Co-authored papers 2
Bruce D Gelb
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Reshma Taneja
Co-authored papers 2
Paul C Boutros
University of California los angeles
Co-authored papers 2
Almudena Bosch
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Christopher P Austin
St. George's University Medical School
Co-authored papers 2
Stuart C Sealfon
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Nadejda M Tsankova
Co-authored papers 2
Robert Sebra
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Lewis C Cantley
Co-authored papers 2
Junjie T Hua
School of Public Health, Sun Yat-sen University
Co-authored papers 2
Michael Fraser
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Dung-Fang Lee
Co-authored papers 2
Housheng Hansen He
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 2
Haiyang Guo
the Second Hospital, Cheeloo College of Medicine, Shandong University
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Release 1.2