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Author Details

Robert E W Hancock
University of British Columbia
1974
726
138
PMIDPaper TitleJournal TitlePublished Year
36928189Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens.Nat Commun2023
37680625Post-COVID symptoms are associated with endotypes reflecting poor inflammatory and hemostatic modulation.Front Immunol2023
37924726Antibiotic failure: Beyond antimicrobial resistance.Drug Resist Updat2023
37090709Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms.Front Immunol2023
37242633Impacts of PEGylation and Glycosylation on the Biological Properties of Host Defense Peptide IDR1018.Pharmaceutics2023
37304268Facilitating systems-level analyses of all-cause and Covid-mediated sepsis through SeptiSearch, a manually-curated compendium of dysregulated gene sets.Front Immunol2023
37201774Dynamic killing effectiveness of mouthrinses and a d-enantiomeric peptide on oral multispecies biofilms grown on dental restorative material surfaces.J Dent2023
36690713Predicting severity in COVID-19 disease using sepsis blood gene expression signatures.Sci Rep2023
36424517The ColR/S two-component system is a conserved determinant of host association across Pseudomonas species.ISME J2023
35019164Gut microbes shape microglia and cognitive function during malnutrition.Glia2022
35653648SPECT/CT Imaging of <sup>111</sup>Ag for the Preclinical Evaluation of Silver-Based Antimicrobial Nanomedicines.ACS Appl Mater Interfaces2022
35612776Assessing the Activity of Antimicrobial Peptides Against Common Marine Bacteria Located in Rotifer (Brachionus plicatilis) Cultures.Probiotics Antimicrob Proteins2022
35369481Targeting the <i>Pseudomonas aeruginosa</i> Virulence Factor Phospholipase C With Engineered Liposomes.Front Microbiol2022
35637237Competition between Pseudomonas aeruginosa and Staphylococcus aureus is dependent on intercellular signaling and regulated by the NtrBC two-component system.Sci Rep2022
35426393Gene Expression Profiling: Identification of Novel Pathways and Potential Biomarkers in Severe Acute Pancreatitis.J Am Coll Surg2022
35386316Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures.Bioact Mater2022
36504765Surviving the host: Microbial metabolic genes required for growth of <i>Pseudomonas aeruginosa</i> in physiologically-relevant conditions.Front Microbiol2022
36421248Novel Alligator Cathelicidin As-CATH8 Demonstrates Anti-Infective Activity against Clinically Relevant and Crocodylian Bacterial Pathogens.Antibiotics (Basel)2022
36312952BosR: A novel biofilm-specific regulator in <i>Pseudomonas aeruginosa</i>.Front Microbiol2022
36240188A transcriptomic analysis of the effects of macrophage polarization and endotoxin tolerance on the response to Salmonella.PLoS One2022
36359854Host Response of Human Epidermis to Methicillin-Resistant <i>Staphylococcus aureus</i> Biofilm Infection and Synthetic Antibiofilm Peptide Treatment.Cells2022
36347894A curated collection of human vaccination response signatures.Sci Data2022
35175731Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on <i>ESKAPE</i> Bacterial Pathogens.ACS Infect Dis2022
35302764Assessing the <i>In Vivo</i> Effectiveness of Cationic Lipid Nanoparticles with a Triple Adjuvant for Intranasal Vaccination against the Respiratory Pathogen <i>Bordetella pertussis</i>.Mol Pharm2022
35027333Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures.EBioMedicine2022
35048687Correction to "Multifunctional Antibiotic-Host Defense Peptide Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response".J Med Chem2022
32684439Ivacaftor or lumacaftor/ivacaftor treatment does not alter the core CF airway epithelial gene response to rhinovirus.J Cyst Fibros2021
35424252Antibiofilm peptides: overcoming biofilm-related treatment failure.RSC Adv2021
33911258Microtiter plate assays to assess antibiofilm activity against bacteria.Nat Protoc2021
33734952Immunomodulatory streptococci that inhibit CXCL8 secretion and NFκB activation are common members of the oral microbiota.J Med Microbiol2021
33927701An Overview of Biological and Computational Methods for Designing Mechanism-Informed Anti-biofilm Agents.Front Microbiol2021
33865931Identification of a crocodylian β-defensin variant from Alligator mississippiensis with antimicrobial and antibiofilm activity.Peptides2021
33692808Different Disease Endotypes in Phenotypically Similar Vasculitides Affecting Small-to-Medium Sized Blood Vessels.Front Immunol2021
33837303Assessing biofilm inhibition and immunomodulatory activity of small amounts of synthetic host defense peptides synthesized using SPOT-array technology.Nat Protoc2021
33777834Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies.Front Cell Infect Microbiol2021
33930077Peptide 1018 inhibits swarming and influences Anr-regulated gene expression downstream of the stringent stress response in Pseudomonas aeruginosa.PLoS One2021
33524525Rapid microwave-based method for the preparation of antimicrobial lignin-capped silver nanoparticles active against multidrug-resistant bacteria.Int J Pharm2021
33495449Human organoid biofilm model for assessing antibiofilm activity of novel agents.NPJ Biofilms Microbiomes2021
34406853RNase III and RNase E Influence Posttranscriptional Regulatory Networks Involved in Virulence Factor Production, Metabolism, and Regulatory RNA Processing in Bordetella pertussis.mSphere2021
34784220Multifunctional Antibiotic-Host Defense Peptide Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response.J Med Chem2021
34424159Genomic insights into the diversity, virulence and resistance of <i>Klebsiella pneumoniae</i> extensively drug resistant clinical isolates.Microb Genom2021
34836612The Pseudomonas aeruginosa whole genome sequence: A 20th anniversary celebration.Adv Microb Physiol2021
34777332Machine Learning-Based Single Cell and Integrative Analysis Reveals That Baseline mDC Predisposition Correlates With Hepatitis B Vaccine Antibody Response.Front Immunol2021
34597746Enzymatically releasable polyethylene glycol - host defense peptide conjugates with improved activity and biocompatibility.J Control Release2021
34328312Rapid Assembly of Infection-Resistant Coatings: Screening and Identification of Antimicrobial Peptides Works in Cooperation with an Antifouling Background.ACS Appl Mater Interfaces2021
34249781NtrBC Selectively Regulates Host-Pathogen Interactions, Virulence, and Ciprofloxacin Susceptibility of <i>Pseudomonas aeruginosa</i>.Front Cell Infect Microbiol2021
34183822Antibiofilm activity of host defence peptides: complexity provides opportunities.Nat Rev Microbiol2021
34215865Testing physiologically relevant conditions in minimal inhibitory concentration assays.Nat Protoc2021
33978706PaIntDB: network-based omics integration and visualization using protein-protein interactions in Pseudomonas aeruginosa.Bioinformatics2021
33200281The use of host defense peptides in root canal therapy in rats.Clin Oral Investig2021
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Collaborators

Simon Fraser University
Co-authored papers 35
St. Paul's Hospital, University of British Columbia
Co-authored papers 20
McGill University
Co-authored papers 13
Telethon Kids Institute
Co-authored papers 8
Co-authored papers 8
South Australian Health and Medical Research Institute
Co-authored papers 7
Smurfit Institute of Genetics, Trinity College of Dublin
Co-authored papers 6
Co-authored papers 5
J. Craig Venter Institute
Co-authored papers 3
Genentech Inc.
Co-authored papers 3
University of Alberta
Co-authored papers 3
University of British Columbia
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
European Bioinformatics Institute
Co-authored papers 3
University of British Columbia
Co-authored papers 3
Wellcome Trust Sanger Institute
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Brandeis University
Co-authored papers 2
University of British Columbia
Co-authored papers 2
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 2
J. Craig Venter Institute
Co-authored papers 2
Harvard T.H. Chan School of Public Health
Co-authored papers 2
The University of British Columbia
Co-authored papers 2
Simon Fraser University
Co-authored papers 2
University of British Columbia
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Boston Children's Hospital, USA Harvard Medical School, Harvard Medical School
Co-authored papers 2
Wellcome Trust Sanger Institute
Co-authored papers 2
University of Calgary
Co-authored papers 2