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Author Details

Sara A Byron
2003
45
22
PMIDPaper TitleJournal TitlePublished Year
38053317Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential.Vet Comp Oncol2024
36609061Genomic and Transcriptomic Predictors of Response from Stereotactic Body Radiation Therapy in Patients with Oligoprogressive Renal Cell Carcinoma.2023
36335489Interrogating the Human Diplome: Computational Methods, Emerging Applications, and Challenges.Methods Mol Biol2023
37603953Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma.Neoplasia2023
36630480Genome-wide analysis of aberrant position and sequence of plasma DNA fragment ends in patients with cancer.Sci Transl Med2023
37248814Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.2023
35852795Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003.Clin Cancer Res2022
35355452A pilot study of genomic-guided induction therapy followed by immunotherapy with difluoromethylornithine maintenance for high-risk neuroblastoma.Cancer Rep (Hoboken)2022
34610968Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion.Cancer Res2021
33826614Identifying treatment options for BRAFV600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial.PLoS One2021
32661119Correlates of clinical benefit from immunotherapy and targeted therapy in metastatic renal cell carcinoma: comprehensive genomic and transcriptomic analysis.Journal for ImmunoTherapy of Cancer2020
32743548Temporospatial genomic profiling in glioblastoma identifies commonly altered core pathways underlying tumor progression.Neurooncol Adv2020
30949446Leveraging Spatial Variation in Tumor Purity for Improved Somatic Variant Calling of Archival Tumor Only Samples.Front Oncol2019
31651965Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer.JAMA Netw Open2019
31881020Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas.PLoS One2019
30264293E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases.Invest New Drugs2019
30537101Bcl-2 inhibitors enhance FGFR inhibitor-induced mitochondrial-dependent cell death in FGFR2-mutant endometrial cancer.Molecular Oncology2019
30861105A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.Int J Cancer2019
31209844Genomics-Enabled Precision Medicine for Cancer.Cancer Treatment and Research2019
29074604Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma.Clin Cancer Res2018
30322893Identification of therapeutic targets in chordoma through comprehensive genomic and transcriptomic analyses.Cold Spring Harbor molecular case studies2018
28314589FGFR2 mutations are associated with poor outcomes in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study.Gynecologic Oncology2017
28586388A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy.PLoS One2017
28446508Enrichment of PI3K-AKT-mTOR Pathway Activation in Hepatic Metastases from Breast Cancer.Clin Cancer Res2017
29052513A method to reduce ancestry related germline false positives in tumor only somatic variant calling.BMC Med Genomics2017
26991655Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer.PLoS One2016
26996076Translating RNA sequencing into clinical diagnostics: opportunities and challenges.Nat Rev Genet2016
25934816Toward precision medicine in glioblastoma: the promise and the challenges.Neuro Oncol2015
25592568An integrated framework for reporting clinically relevant biomarkers from paired tumor/normal genomic and transcriptomic sequencing data in support of clinical trials in personalized medicine.Pac Symp Biocomput2015
25237832Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway.Oncotarget2014
23059386XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts.Anti-Cancer Drugs2013
23908597The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors.Neoplasia2013
23039341Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status.Molecular Cancer2012
22383975FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features.PLoS ONE2012
23060048Fibroblast growth factor receptor inhibition synergizes with Paclitaxel and Doxorubicin in endometrial cancer cells.International Journal of Gynecological Cancer2012
23056468Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer.PLoS ONE2012
20106510FGFR2 mutations are rare across histologic subtypes of ovarian cancer.Gynecologic Oncology2010
19147536Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma.Mol Cancer Res2009
19243295FGFR2 as a molecular target in endometrial cancer.Future Oncology2009
19564416Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix.Mol Cell Biol2009
18757403Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation.Cancer Research2008
18819936Progesterone receptor-B regulation of insulin-like growth factor-stimulated cell migration in breast cancer cells via insulin receptor substrate-2.Molecular Cancer Research2008
18829493Brivanib alaninate, a dual inhibitor of vascular endothelial growth factor receptor and fibroblast growth factor receptor tyrosine kinases, induces growth inhibition in mouse models of human hepatocellular carcinoma.Clinical Cancer Research2008
17043687Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.British Journal of Cancer2006
14613033Potential therapeutic strategies to interrupt insulin-like growth factor signaling in breast cancer.Seminars in Oncology2003
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