Author details

Full Name

Mike O'Donnell

Affiliation

The Rockefeller University

ORCID

Career Start Year

1985

Papers

278

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37205351	Molecular choreography of primer synthesis by the eukaryotic Pol Î±-primase.	bioRxiv	2023
37392384	Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification on biology.	Cell Rep	2023
37344454	Molecular choreography of primer synthesis by the eukaryotic Pol Î±-primase.	Nat Commun	2023
37205533	Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.	bioRxiv	2023
35314830	DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp.	Nat Struct Mol Biol	2022
35829698	Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.	Elife	2022
36442086	SV40 T-antigen uses a DNA shearing mechanism to initiate origin unwinding.	Proc Natl Acad Sci U S A	2022
36418314	Smc5/6's multifaceted DNA binding capacities stabilize branched DNA structures.	Nat Commun	2022
36215487	Origin recognition complex harbors an intrinsic nucleosome remodeling activity.	Proc Natl Acad Sci U S A	2022
35999198	Nucleosome-directed replication origin licensing independent of a consensus DNA sequence.	Nat Commun	2022
35934475	Optimizing CMG helicase and CMG-dependent replication assays by designing DNA fork substrates and choosing nucleotide analogues for helicase preloading.	Methods Enzymol	2022
36116108	Unexpected new insights into DNA clamp loaders: Eukaryotic clamp loaders contain a second DNA site for recessed 5' ends that facilitates repair and signals DNA damage: Eukaryotic clamp loaders contain a second DNA site for recessed 5' ends that facilitates repair and signals DNA damage.	Bioessays	2022
35042821	CMG helicase can use ATPÎ³S to unwind DNA: Implications for the rate-limiting step in the reaction mechanism.	Proc Natl Acad Sci U S A	2022
33252731	The DNA Replication Machine: Structure and Dynamic Function.	Subcell Biochem	2021
33847559	Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction.	Elife	2021
33785598	A unique Malpighian tubule architecture in <i>Tribolium castaneum</i> informs the evolutionary origins of systemic osmoregulation in beetles.	Proc Natl Acad Sci U S A	2021
33523561	Water skating: How polymerase sliding clamps move on DNA.	FEBS J	2021
34742395	Expression of recombinant multi-protein complexes in Saccharomyces cerevisiae.	Methods Enzymol	2021
32572031	Structure of the polymerase Îµ holoenzyme and atomic model of the leading strand replisome.	Nat Commun	2020
31704183	Tunability of DNA Polymerase Stability during Eukaryotic DNA Replication.	Mol Cell	2020
32019936	DNA unwinding mechanism of a eukaryotic replicative CMG helicase.	Nat Commun	2020
33199603	Replisome bypass of a protein-based R-loop block by Pif1.	Proc Natl Acad Sci U S A	2020
33300972	Anatomy of a twin DNA replication factory.	Biochem Soc Trans	2020
33203675	Structure of eukaryotic DNA polymerase Î´ bound to the PCNA clamp while encircling DNA.	Proc Natl Acad Sci U S A	2020
30598452	Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression.	Proc Natl Acad Sci U S A	2019
31589141	Ctf4 organizes sister replisomes and Pol Î± into a replication factory.	Elife	2019
31560343	Getting ready for DNA duplication.	Elife	2019
31527759	Nuclease dead Cas9 is a programmable roadblock for DNA replication.	Sci Rep	2019
31348887	Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase.	Cell	2019
31282859	An explanation for origin unwinding in eukaryotes.	Elife	2019
30792289	DNA replication from two different worlds.	Science	2019
30782813	Mathematical description of eukaryotic chromosome replication.	Proc Natl Acad Sci U S A	2019
29259108	Replication fork convergence at termination: A multistep process.	Proc Natl Acad Sci U S A	2018
29379175	The ring-shaped hexameric helicases that function at DNA replication forks.	Nat Struct Mol Biol	2018
29405332	The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism.	Bioessays	2018
28069954	Quality control mechanisms exclude incorrect polymerases from the eukaryotic replication fork.	Proc Natl Acad Sci U S A	2017
28267969	DNA Replication: How Does a Sliding Clamp Slide?	Curr Biol	2017
28346143	Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase.	Elife	2017
28096349	Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.	Proc Natl Acad Sci U S A	2017
29357060	Architecture of the Saccharomyces cerevisiae Replisome.	Adv Exp Med Biol	2017
29036608	Insights into RNA polymerase catalysis and adaptive evolution gained from mutational analysis of a locus conferring rifampicin resistance.	Nucleic Acids Res	2017
29082290	<i>In vitro</i> Assays for Eukaryotic Leading/Lagging Strand DNA Replication.	Bio Protoc	2017
29078353	Mutagenic cost of ribonucleotides in bacterial DNA.	Proc Natl Acad Sci U S A	2017
28923950	Single-molecule visualization of <i>Saccharomyces cerevisiae</i> leading-strand synthesis reveals dynamic interaction between MTC and the replisome.	Proc Natl Acad Sci U S A	2017
28869037	Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks.	Elife	2017
27003891	The Eukaryotic Replisome Goes Under the Microscope.	Curr Biol	2016
28042596	Bacterial and Eukaryotic Replisome Machines.	JSM Biochem Mol Biol	2016
27241931	The Eukaryotic Replication Machine.	Enzymes	2016
27298353	Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest.	Proc Natl Acad Sci U S A	2016
27416113	Reconstitution of a eukaryotic replisome reveals the mechanism of asymmetric distribution of DNA polymerases.	Nucleus	2016

1 - 50 of 278

Yoori Kim

Daegu Gyeongbuk Institute of Science and Technology (DGIST)

Career Start Year 2011

Number of shared co-authors 0

Vandna Kukshal

Washington University

Career Start Year 2007

Number of shared co-authors 0

Arkadiusz W Kulczyk

Institute for Quantitative Biomedicine, Rutgers University

Career Start Year 2004

Number of shared co-authors 1

Marc C Morais

University of Texas Medical Branch

Career Start Year 2000

Number of shared co-authors 2

Peter R Weigele

New England Biolabs Inc.

Career Start Year 1998

Number of shared co-authors 0

Jan P Erzberger

UT Southwestern Medical Center

Career Start Year 1998

Number of shared co-authors 2

Rachel A Mooney

University of Wisconsin-Madison

Career Start Year 1997

Number of shared co-authors 2

Craig D Kaplan

University of Pittsburgh

Career Start Year 1995

Number of shared co-authors 0

David A Bushnell

Stanford University

Career Start Year 1994

Number of shared co-authors 1

Grant W Brown

University of Toronto, 1 King's College Circle

Career Start Year 1991

Number of shared co-authors 1

Jesper Q Svejstrup

Panum Institute, University of Copenhagen

Career Start Year 1990

Number of shared co-authors 0

Seth A Darst

The Rockefeller University

Career Start Year 1988

Number of shared co-authors 5

Ralph E Davis

Stanford University School of Medicine

Career Start Year 1988

Number of shared co-authors 1

Francisco J Asturias

University of Colorado Anschutz Medical Campus

Career Start Year 1988

Number of shared co-authors 4

Mirit I Aladjem

National Cancer Institute, Center for Cancer Research

Career Start Year 1988

Number of shared co-authors 0

Jennifer A Doudna

Innovative Genomics Institute, University of California berkeley

Career Start Year 1987

Number of shared co-authors 3

Arun Malhotra

University of Miami Miller School of Medicine

Career Start Year 1986

Number of shared co-authors 1

Sergei Borukhov

Rowan University School of Osteopathic Medicine

Career Start Year 1985

Number of shared co-authors 1

Opher Gileadi

Structural Genomics Consortium Karolinska Institute Stockholm Sweden.

Career Start Year 1984

Number of shared co-authors 2

Susan T Lovett

Brandeis University

Career Start Year 1983

Number of shared co-authors 0

Wolf-Dietrich Heyer

University of California davis

Career Start Year 1982

Number of shared co-authors 1

Robert Landick

University of Wisconsin-Madison

Career Start Year 1980

Number of shared co-authors 4

Kalappa Muniyappa

Indian Institute of Science

Career Start Year 1979

Number of shared co-authors 0

John A Tainer

The University of Texas MD Anderson Cancer Center

Career Start Year 1975

Number of shared co-authors 2

Richard D Kolodner

Ludwig Institute for Cancer Research San Diego Branch

Career Start Year 1972

Number of shared co-authors 0

Stephen C Harvey

University of Pennsylvania

Career Start Year 1972

Number of shared co-authors 1

Michael R Botchan

University of California berkeley

Career Start Year 1970

Number of shared co-authors 0

Jack F Greenblatt

College Street, University of Toronto

Career Start Year 1969

Number of shared co-authors 0

Roger D Kornberg

Stanford University

Career Start Year 1965

Number of shared co-authors 1

Thomas E Wilson

University of Michigan ann arbor

Career Start Year 1955

Number of shared co-authors 0

row(s) 1 - 30 of 30

John Kuriyan

University of California berkeley

Co-authored papers 36

Rene Onrust

University of California san francisco

Co-authored papers 12

Shixin Liu

The Rockefeller University

Co-authored papers 4

Brian T Chait

The Rockefeller University

Co-authored papers 4

Stephen Anderson

Center for Advanced Biotechnology and Medicine, Rutgers University

Co-authored papers 2

J. Wade Harper

Harvard Medical School

Co-authored papers 1

Michael P Rout

The Rockefeller University

Co-authored papers 1

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

David J Dilworth

Institute for Systems Biology

Co-authored papers 1

Carol V Robinson

University of Oxford

Co-authored papers 1

Michael G Kurilla

National Center for Advancing Translational Sciences, National Institutes of Health

Co-authored papers 1

Steven C Slater

Great Lakes Bioenergy Research Center, the University of Wisconsin-Madison

Co-authored papers 1

Kelly R Molloy

The Rockefeller University

Co-authored papers 1

Peter Walter

University of California san francisco

Co-authored papers 1

Stephen J Elledge

Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School

Co-authored papers 1

Brian D Guenther

University of Michigan ann arbor

Co-authored papers 1

Carlos Bustamante

University of California berkeley

Co-authored papers 1

Argyris Politis

King's College London

Co-authored papers 1

John D Aitchison

Center for Global Infectious Disease Research, Seattle Children's Research Institute

Co-authored papers 1

Shibai Li

Memorial Sloan-Kettering Cancer Center

Co-authored papers 1

Xiaolan Zhao

Memorial Sloan-Kettering Cancer Center

Co-authored papers 1

Yi Shi

College of Medicine, Yangzhou University

Co-authored papers 1

Emily C Beckwitt

Howard Hughes Medical Institute, The Rockefeller University

Co-authored papers 1

1 - 23

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