Author details

Full Name

Ehud Y Isacoff

Affiliation

University of California berkeley

ORCID

Career Start Year

1988

Papers

179

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36928458	Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.	Nat Struct Mol Biol	2023
37905049	Development of covalent chemogenetic K<sub>2P</sub> channel activators.	bioRxiv	2023
37586061	Optical Control of Dopamine D2-like Receptors with Cell-Specific Fast-Relaxing Photoswitches.	J Am Chem Soc	2023
37844228	Ciliary localization of a light-activated neuronal GPCR shapes behavior.	Proc Natl Acad Sci U S A	2023
37693614	Step-wise activation of a Family C GPCR.	bioRxiv	2023
38092773	Homo- and hetero-dimeric subunit interactions set affinity and efficacy in metabotropic glutamate receptors.	Nat Commun	2023
37001505	Negative allosteric modulation of the glucagon receptor by RAMP2.	Cell	2023
35017509	Determinants of synapse diversity revealed by super-resolution quantal transmission and active zone imaging.	Nat Commun	2022
35749908	Photopharmacology for vision restoration.	Curr Opin Pharmacol	2022
33976221	Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation.	Nat Commun	2021
34785691	In vivo volumetric imaging of calcium and glutamate activity at synapses with high spatiotemporal resolution.	Nat Commun	2021
34362914	Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors.	Nat Commun	2021
34115935	Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor.	J Am Chem Soc	2021
32494711	Fast widefield imaging of neuronal structure and function with optical sectioning in vivo.	Sci Adv	2020
32788354	Dimer interaction in the Hv1 proton channel.	Proc Natl Acad Sci U S A	2020
32985972	Experience, circuit dynamics, and forebrain recruitment in larval zebrafish prey capture.	Elife	2020
32469525	Optical Control of Lysophosphatidic Acid Signaling.	J Am Chem Soc	2020
30874546	Restoration of high-sensitivity and adapting vision with a cone opsin.	Nat Commun	2019
31804469	Conformational pathway provides unique sensitivity to a synaptic mGluR.	Nat Commun	2019
31291105	Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor.	J Am Chem Soc	2019
31036923	Optical control of sphingosine-1-phosphate formation and function.	Nat Chem Biol	2019
29188513	Optogenetic Retinal Gene Therapy with the Light Gated GPCR Vertebrate Rhodopsin.	Methods Mol Biol	2018
29867144	Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system.	Nat Chem Biol	2018
29874052	Restoring Vision to the Blind with Chemical Photoswitches.	Chem Rev	2018
29535310	Author Correction: Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor.	Nat Commun	2018
28690101	Precise modulation of neuronal activity with synthetic photoswitchable ligands.	Curr Opin Neurobiol	2017
28360219	A new mechanism of voltage-dependent gating exposed by K<sub>V</sub>10.1 channels interrupted between voltage sensor and pore.	J Gen Physiol	2017
28396573	Synapses in the spotlight with syntheticÂ optogenetics.	EMBO Rep	2017
28396447	Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors.	Proc Natl Acad Sci U S A	2017
28285823	Input-Specific Plasticity and Homeostasis at the Drosophila Larval Neuromuscular Junction.	Neuron	2017
29192252	Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor.	Nat Commun	2017
29166564	Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist.	J Am Chem Soc	2017
28752108	Measuring Behavioral Individuality in the Acoustic Startle Behavior in Zebrafish.	Bio Protoc	2017
28564609	Sequential Steps of CRAC Channel Activation.	Cell Rep	2017
26869877	A Toolkit for Orthogonal and in vivo Optical Manipulation of Ionotropic Glutamate Receptors.	Front Mol Neurosci	2016
28090283	Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO).	Chem Sci	2016
26546674	Cooperative Binding of Stromal Interaction Molecule 1 (STIM1) to the N and C Termini of Calcium Release-activated Calcium Modulator 1 (Orai1).	J Biol Chem	2016
27641494	Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors.	Neuron	2016
27397519	Neuromodulatory Regulation of Behavioral Individuality in Zebrafish.	Neuron	2016
27172609	MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans.	G3 (Bethesda)	2016
26941331	Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins.	Mol Biol Cell	2016
27017828	Molecular basis for multimerization in the activation of the epidermal growth factor receptor.	Elife	2016
27035963	Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels.	Proc Natl Acad Sci U S A	2016
26979622	A phosphotyrosine switch regulates organic cation transporters.	Nat Commun	2016
26878552	Allosteric substrate switching in a voltage-sensing lipid phosphatase.	Nat Chem Biol	2016
26929991	A family of photoswitchable NMDA receptors.	Elife	2016
25560069	Fluorescent labeling for patch-clamp fluorometry (PCF) measurements of real-time protein motion in ion channels.	Methods Mol Biol	2015
26324944	Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans.	Proc Natl Acad Sci U S A	2015
26258295	Conformational dynamics of a class C G-protein-coupled receptor.	Nature	2015
27162996	Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand.	ACS Cent Sci	2015

1 - 50 of 179

William T Keenan

Johns Hopkins University

Career Start Year 2016

Number of shared co-authors 0

Huong T Kratochvil

Department of Pharmaceutical Chemistry, University of California-San Francisco

Career Start Year 2015

Number of shared co-authors 1

Kate L White

Lawrence Berkeley National Laboratory

Career Start Year 2012

Number of shared co-authors 1

Alpay B Seven

Stanford University School of Medicine

Career Start Year 2011

Number of shared co-authors 0

Michael G Leitner

Institute of Physiology and Pathophysiology, Philipps University Marburg

Career Start Year 2011

Number of shared co-authors 0

Keenan C Taylor

Vanderbilt University

Career Start Year 2009

Number of shared co-authors 1

Aashish Manglik

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 2008

Number of shared co-authors 1

Andrew C Kruse

Blavatnik Institute, Harvard Medical School

Career Start Year 2008

Number of shared co-authors 0

Guisheng Zhong

ShanghaiTech University

Career Start Year 2006

Number of shared co-authors 1

Edward S Boyden

McGovern Institute for Brain Research

Career Start Year 2003

Number of shared co-authors 1

Georgios Skiniotis

Stanford University School of Medicine

Career Start Year 1999

Number of shared co-authors 0

Daniela Boassa

University of California San Diego

Career Start Year 1999

Number of shared co-authors 0

Agnes Thalhammer

University of Trieste

Career Start Year 1999

Number of shared co-authors 1

Dominik Oliver

Institute of Physiology and Pathophysiology, Philipps-University Marburg

Career Start Year 1997

Number of shared co-authors 0

Xiaowei Zhuang

Howard Hughes Medical Institute, Harvard University

Career Start Year 1994

Number of shared co-authors 1

Michael H B Stowell

University of Colorado Boulder

Career Start Year 1993

Number of shared co-authors 1

Vadim A Klenchin

University of Wisconsin-Madison

Career Start Year 1991

Number of shared co-authors 1

Stefan Gr??nder

Institute of Physiology, RWTH Aachen University

Career Start Year 1991

Number of shared co-authors 0

Ardem Patapoutian

Howard Hughes Medical Institute

Career Start Year 1990

Number of shared co-authors 0

Carlos G Vanoye

Feinberg School of Medicine, Northwestern University

Career Start Year 1990

Number of shared co-authors 0

Atsushi Miyawaki

RIKEN Center for Advanced Photonics

Career Start Year 1989

Number of shared co-authors 1

Pei Tang

Sichuan University

Career Start Year 1989

Number of shared co-authors 1

Michael P Kavanaugh

University of Montana.

Career Start Year 1987

Number of shared co-authors 0

Senyon Choe

Joint Center for Biosciences

Career Start Year 1986

Number of shared co-authors 2

Paul A Slesinger

Friedman Brain Institute, Icahn School of Medicine at Mount Sinai

Career Start Year 1985

Number of shared co-authors 1

Thomas J Deerinck

National Center for Microscopy and Imaging Research, University of California

Career Start Year 1982

Number of shared co-authors 0

Craig Montell

University of California santa barbara

Career Start Year 1982

Number of shared co-authors 0

Steven A Siegelbaum

Columbia University

Career Start Year 1976

Number of shared co-authors 0

Roger Y Tsien

University of California

Career Start Year 1975

Number of shared co-authors 0

Richard W Tsien

New York University Grossman School of Medicine

Career Start Year 1968

Number of shared co-authors 0

row(s) 1 - 30 of 30

Shashank Bharill

University of California berkeley

Co-authored papers 9

Lily Yeh Jan

Co-authored papers 8

Daniel L Minor

Cardiovascular Research Institute, University of California san francisco

Co-authored papers 6

Eun Young Kim

College of Korean Medicine, Kyung Hee University

Co-authored papers 2

Liang Tong

Columbia University

Co-authored papers 2

Corey S Goodman

Co-authored papers 2

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Jan H M Schellens

Department of Pharmaceutical Sciences, Utrecht University

Co-authored papers 1

Su Sien Ong

St. Jude Children's Research Hospital

Co-authored papers 1

Alex Sparreboom

Ohio State University

Co-authored papers 1

Navjotsingh Pabla

The Ohio State University

Co-authored papers 1

Giuliano Ciarimboli

University Hospital Munster

Co-authored papers 1

Loren L Looger

Howard Hughes Medical Institute

Co-authored papers 1

Robert B Diasio

Mayo Clinic

Co-authored papers 1

Sharyn D Baker

Ohio State University

Co-authored papers 1

Rachel A Ness

4Department of Pharmacy, Memphis Veterans Affairs Medical Center

Co-authored papers 1

Lie Li

Sino-French Hoffmann Institute, Guangzhou Medical University

Co-authored papers 1

Jason A Sprowl

School of Pharmacy and Pharmaceutical Sciences, University at Buffalo

Co-authored papers 1

Barry Honig

Columbia University Irving Medical Center

Co-authored papers 1

David V Schaffer

University of California berkeley

Co-authored papers 1

Richard Benton

Center for Integrative Genomics, University of Lausanne

Co-authored papers 1

Anne T Nies

and University of Tuebingen, University of Tuebingen

Co-authored papers 1

Carlos Bustamante

University of California berkeley

Co-authored papers 1

Shuiying Hu

The Ohio State University

Co-authored papers 1

Taosheng Chen

St. Jude Children's Research Hospital

Co-authored papers 1

Guoqing Du

Second Affiliated Hospital of Harbin Medical University

Co-authored papers 1

John Kuriyan

University of California berkeley

Co-authored papers 1

Matthias Schwab

and of Biochemistry and Pharmacy, University of Tuebingen

Co-authored papers 1

Wenwei Lin

St. Jude Children's Research Hospital

Co-authored papers 1

Adrian Stecula

Schools of Pharmacy and Medicine, University of California san francisco

Co-authored papers 1

1 - 30

Author Details

Column Actions

Recommended Authors

Collaborators