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Author Details

Todd E Golde
Emory Center for Neurodegenerative Disease
1986
320
91
PMIDPaper TitleJournal TitlePublished Year
37903991Free-water imaging reveals unique brain microstructural deficits in hispanic individuals with Dementia.Brain Imaging Behav2024
37628569Brain Targeted AAV1-GALC Gene Therapy Reduces Psychosine and Extends Lifespan in a Mouse Model of Krabbe Disease.Genes (Basel)2023
34813500Alzheimer's disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions.J Clin Invest2022
35352880AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model.EMBO Mol Med2022
35550593Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.Commun Biol2022
35494163Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts.Free Neuropathol2022
36535953Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance.NPJ Parkinsons Dis2022
36482422Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy.Mol Neurodegener2022
36310167Common features of neurodegenerative disease: exploring the brain-eye connection and beyond (Part 1): the 2021 pre-symposium of the 15th international conference on Alzheimer's and Parkinson's diseases.Mol Neurodegener2022
35897046Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways.Alzheimers Res Ther2022
36056345LRP1 is a neuronal receptor for α-synuclein uptake and spread.Mol Neurodegener2022
36316783Common features of neurodegenerative disease: exploring the brain-eye connection and beyond (part 2): the 2021 pre-symposium of the 15th international conference on Alzheimer's and Parkinson's diseases.Mol Neurodegener2022
35248124Alzheimer's disease - the journey of a healthy brain into organ failure.Mol Neurodegener2022
34906980Association of Cognitive Impairment With Free Water in the Nucleus Basalis of Meynert and Locus Coeruleus to Transentorhinal Cortex Tract.Neurology2022
35328748Intracerebral but Not Peripheral Infection of Live <i>Porphyromonas gingivalis</i> Exacerbates Alzheimer's Disease Like Amyloid Pathology in APP-TgCRND8 Mice.Int J Mol Sci2022
35229269Disease-Modifying Therapies for Alzheimer's Disease: More Questions than Answers.Neurotherapeutics2022
33293690Targeting Notch in oncology: the path forward.Nat Rev Drug Discov2021
33741985Il-10 signaling reduces survival in mouse models of synucleinopathy.NPJ Parkinsons Dis2021
33781287Precision therapeutic targets for COVID-19.Virol J2021
33833060Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.Proc Natl Acad Sci U S A2021
33496840Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions.Acta Neuropathol2021
34127518Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo.Life Sci Alliance2021
33957936Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy.Mol Neurodegener2021
33216030Utility of Plasma Neurofilament Light in the 1Florida Alzheimer's Disease Research Center (ADRC).J Alzheimers Dis2021
33128896Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes.Mol Ther2021
33480174Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease.Alzheimers Dement2021
32252825Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis.Acta Neuropathol Commun2020
31903524Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy.Mol Neurobiol2020
31894407Diffusion magnetic resonance imaging-derived free water detects neurodegenerative pattern induced by interferon-γ.Brain Struct Funct2020
33069251Aÿ40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aÿ42 toxicity in Drosophila.Alzheimers Res Ther2020
32665013Fyn depletion ameliorates tau<sup>P301L</sup>-induced neuropathology.Acta Neuropathol Commun2020
32690681Metformin inhibits RAN translation through PKR pathway and mitigates disease in <i>C9orf72</i> ALS/FTD mice.Proc Natl Acad Sci U S A2020
32814038Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data across 27 Tissue Types.Cell Rep2020
32668255Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.Cell Rep2020
32284590Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.Nat Med2020
32122372Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS.Mol Neurodegener2020
32152461Do infections have a role in the pathogenesis of Alzheimer disease?Nat Rev Neurol2020
32457739CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells.Front Immunol2020
32430033γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not.Alzheimers Res Ther2020
32426924Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community.Alzheimers Dement2020
30639851ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons.iScience2019
31685865Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus.Sci Rep2019
31791377Organotypic brain slice cultures to model neurodegenerative proteinopathies.Mol Neurodegener2019
31472250Neurite orientation dispersion and density imaging reveals white matter and hippocampal microstructure changes produced by Interleukin-6 in the TgCRND8 mouse model of amyloidosis.Neuroimage2019
31470214Free-water imaging of the hippocampus is a sensitive marker of Alzheimer's disease.Neuroimage Clin2019
31467300Cardiac MLC2 kinase is localized to the Z-disc and interacts with α-actinin2.Sci Rep2019
31467037An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.J Exp Med2019
31261380Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy.Hum Mol Genet2019
31425915ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons.iScience2019
31417955A cognitive stress test for prodromal Alzheimer's disease: Multiethnic generalizability.Alzheimers Dement (Amst)2019
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Dean M Hartley
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Paul S Aisen
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Lennart Mucke
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W S Griffin
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Collaborators

Paramita Chakrabarty
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 51
Yona Levites
Emory University School of Medicine
Co-authored papers 41
Pritam Das
Institute of Medical Sciences, Banaras Hindu University
Co-authored papers 39
Dennis W Dickson
Mayo Clinic Jacksonville
Co-authored papers 36
Carolina Ceballos-Diaz
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 35
Steven G Younkin
Mayo Clinic
Co-authored papers 32
Pedro E Cruz
College of Medicine, University of Florida
Co-authored papers 29
Lucio Miele
Louisiana State University Health Sciences Center
Co-authored papers 27
Nil??fer Ertekin-Taner
Mayo Clinic
Co-authored papers 19
Brenda D Moore
College of Medicine, University of Florida
Co-authored papers 18
Nathan D Price
Institute for Systems Biology
Co-authored papers 17
Mariet Allen
Mayo Clinic
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Xue Wang
Mayo Clinic
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Awilda M Rosario
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 15
Christopher Janus
College of Medicine, University of Florida
Co-authored papers 14
Cory C Funk
Institute for Systems Biology
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Amanda N Sacino
Johns Hopkins University School of Medicine
Co-authored papers 12
Minerva M Carrasquillo
Mayo Clinic
Co-authored papers 9
Douglas Galasko
Co-authored papers 9
Ranjan Duara
Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center
Co-authored papers 8
Rong Wang
Co-authored papers 8
Kevin H Strang
College of Medicine, University of Florida
Co-authored papers 8
Jeremy D Burgess
Mayo Clinic
Co-authored papers 8
Karen N McFarland
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 7
Kimberly G Malphrus
Mayo Clinic Florida
Co-authored papers 7
Yan W Asmann
Mayo Clinic
Co-authored papers 6
Curtis S Younkin
Mayo Clinic
Co-authored papers 6
Christophe Verbeeck
Mayo Clinic College of Medicine
Co-authored papers 6
Neill R Graff-Radford
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Co-authored papers 6
Allan I Levey
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Release 1.2