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Author Details
Full Name
Carsten Skarke
Affiliation
University of Pennsylvania.
ORCID
Career Start Year
1995
Papers
61
H Index
25
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36824952
Diurnal rhythmicity of wearable device-measured wrist temperature predicts future disease incidence in the UK Biobank.
Res Sq
2023
37808824
Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms.
bioRxiv
2023
37620332
Diurnal rhythms of wrist temperature are associated with future disease risk in the UK Biobank.
Nat Commun
2023
37689782
Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms.
Nat Commun
2023
37105582
Modulation of the Immune Response to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination by Nonsteroidal Anti-Inflammatory Drugs.
J Pharmacol Exp Ther
2023
37205602
Prognostic utility of rhythmic components in 24-hour ambulatory blood pressure monitoring for the risk stratification of chronic kidney disease patients with cardiovascular co-morbidity.
medRxiv
2023
34724846
Nitecap: An Exploratory Circadian Analysis Web Application.
J Biol Rhythms
2022
35332134
No increase in inflammation in late-life major depression screened to exclude physical illness.
Transl Psychiatry
2022
33342316
Guidelines for the design and conduct of human clinical trials on ingestion-time differences - chronopharmacology and chronotherapy - of hypertension medications.
Chronobiol Int
2021
34976917
Considerations for the Safe Operation of Schools During the Coronavirus Pandemic.
Front Public Health
2021
32812805
Diet-Epigenome Axis.
Circ Genom Precis Med
2020
29290411
CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis.
EBioMedicine
2018
29215023
A Pilot Characterization of the Human Chronobiome.
Sci Rep
2017
29107287
Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury.
Mol Metab
2017
26180051
Bioactive products formed in humans from fish oils.
J Lipid Res
2015
26332979
Molecular clocks and the human condition: approaching their characterization in human physiology and disease.
Diabetes Obes Metab
2015
25450471
Selective COX-2 inhibitors suppress prostacyclin.
Clin Ther
2014
23092618
Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome(®)) of Boswellia extract.
Fitoterapia
2013
27121942
GCG100649, A Novel Cyclooxygenase-2 Inhibitor, Exhibits a Drug Disposition Profile in Healthy Volunteers Compatible With High Affinity to Carbonic Anhydrase-I/II: Preliminary Dose-Exposure Relationships to Define Clinical Development Strategies.
Clin Pharmacol Drug Dev
2013
23775505
Non-invasive combined surrogates of remifentanil blood concentrations with relevance to analgesia.
Naunyn Schmiedebergs Arch Pharmacol
2013
22167571
Increased bioavailability of 11-keto-β-boswellic acid following single oral dose frankincense extract administration after a standardized meal in healthy male volunteers: modeling and simulation considerations for evaluating drug exposures.
J Clin Pharmacol
2012
23150076
Myrtucommulone from Myrtus communis: metabolism, permeability, and systemic exposure in rats.
Planta Med
2012
22278334
Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649.
Clin Pharmacol Ther
2012
20375362
Training translators for smart drug discovery.
Sci Transl Med
2010
19374837
On the interference of boswellic acids with 5-lipoxygenase: mechanistic studies in vitro and pharmacological relevance.
Eur J Pharmacol
2009
19648270
Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense.
J Immunol
2009
18085997
Pyrosequencing of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance.
Pharmacogenomics
2007
17916229
Effects of selective COX-2 inhibition on prostanoids and platelet physiology in young healthy volunteers.
J Thromb Haemost
2007
16515396
Rapid identification of three functionally relevant polymorphisms in the OATP1B1 transporter gene using Pyrosequencing.
Pharmacogenomics
2006
17178263
The cyclooxygenase 2 genetic variant -765G>C does not modulate the effects of celecoxib on prostaglandin E2 production.
Clin Pharmacol Ther
2006
16413243
Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action.
Clin Pharmacol Ther
2006
16413240
Evidence for morphine-independent central nervous opioid effects after administration of codeine: contribution of other codeine metabolites.
Clin Pharmacol Ther
2006
15704610
Comparison of two screening methods for in-house genotyping in clinical pharmacology units.
Int J Clin Pharmacol Ther
2005
16153398
The 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression.
Clin Pharmacol Ther
2005
16307269
Rapid genotyping for relevant CYP1A2 alleles by pyrosequencing.
Eur J Clin Pharmacol
2005
15830250
[Fundamental principles of clinical trials].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
2005
15982815
Is morphine-3-glucuronide of therapeutic relevance?
Pain
2005
15049432
Single-step identification of all length polymorphisms in the UGT1A1 gene promoter.
Int J Clin Pharmacol Ther
2004
15530129
Genetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives.
Clin Pharmacokinet
2004
15564947
Probenecid interacts with the pharmacokinetics of morphine-6-glucuronide in humans.
Anesthesiology
2004
14981031
Comprehensive mu-opioid-receptor genotyping by pyrosequencing.
Clin Chem
2004
12545149
Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers.
Clin Pharmacol Ther
2003
12895198
Pharmacokinetics of morphine are not altered in subjects with Gilbert's syndrome.
Br J Clin Pharmacol
2003
14559207
Simultaneous screening for three mutations in the ABCB1 gene.
Genomics
2003
14594747
Olfactory function in mild cognitive impairment and Alzheimer's disease: an investigation using psychophysical and electrophysiological techniques.
Am J Psychiatry
2003
14534517
Respiratory and miotic effects of morphine in healthy volunteers when P-glycoprotein is blocked by quinidine.
Clin Pharmacol Ther
2003
14583678
Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers.
Pharmacogenetics
2003
11773859
The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine.
Pharmacogenetics
2002
12189362
Pharmacokinetic modeling to predict morphine and morphine-6-glucuronide plasma concentrations in healthy young volunteers.
Clin Pharmacol Ther
2002
12357145
Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity?
Anesthesiology
2002
1 - 50 of 61
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Collaborators
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Perelman School of Medicine, University of Pennsylvania
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Perelman School of Medicine, University of Pennsylvania Philadelphia
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University of Pennsylvania.
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Perelman School of Medicine, University of Pennsylvania
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Perelman School of Medicine, University of Pennsylvania
Co-authored papers
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Co-authored papers
2
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Perelman School of Medicine, University of Pennsylvania
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Children's Hospital of Philadelphia
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Vagelos College of Physicians and Surgeons, Columbia University
Co-authored papers
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Milton Pividori
Perelman School of Medicine, University of Pennsylvania
Co-authored papers
1
Chun Su
Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia
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National Institute of Diabetes and Digestive and Kidney Diseases
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Iftikhar J Kullo
Mayo Clinic
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Christian Hoffmann
Food Research Center (FoRC)
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1
Seth D Rhoades
University of Pennsylvania
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1
Thomas S Price
at the University of Pennsylvania Perelman School of Medicine
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Kyle Bittinger
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