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Author Details

Andreas Bracher
Max-Planck-Institute of Biochemistry
1995
100
43
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36520302Nucleotide Exchange Factors for Hsp70 Molecular Chaperones: GrpE, Hsp110/Grp170, HspBP1/Sil1, and BAG Domain Proteins.Subcell Biochem2023
36325051Ebola and Marburg virus VP35 coiled-coil validated as antiviral target by tripartite split-GFP complementation.iScience2022
35521968The chaperone Clusterin in neurodegeneration-friend or foe?Bioessays2022
33039147High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2.Biochem Biophys Res Commun2021
33843131Macrocyclic FKBP51 Ligands Define a Transient Binding Mode with Enhanced Selectivity.Angew Chem Int Ed Engl2021
34381050The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model.Nat Commun2021
34820091Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides.Chem Sci2021
34650037The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends.Nat Commun2021
32339190Structure and conformational cycle of a bacteriophage-encoded chaperonin.PLoS One2020
31800244A Novel Decalin-Based Bicyclic Scaffold for FKBP51-Selective Ligands.J Med Chem2020
33153600Reaction rate ambiguities for perturbed spectroscopic data: Theory and implementation.Anal Chim Acta2020
32979320Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes.Cell2020
30675061Rubisco condensate formation by CcmM in β-carboxysome biogenesis.Nature2019
30950829Crystal structure of phosphoribulokinase from Synechococcus sp. strain PCC 6301.Acta Crystallogr F Struct Biol Commun2019
30876804Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2.Mol Cell2019
30482729Structures of Ebola and Reston Virus VP35 Oligomerization Domains and Comparative Biophysical Characterization in All Ebolavirus Species.Structure2019
29336887GroEL Ring Separation and Exchange in the Chaperonin Reaction.Cell2018
29578710Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins.J Med Chem2018
28580920Crystal structure of the Thermoplasma acidophilum protein Ta1207.Acta Crystallogr F Struct Biol Commun2017
28125284Biogenesis and Metabolic Maintenance of Rubisco.Annu Rev Plant Biol2017
29217567Plant RuBisCo assembly in <i>E. coli</i> with five chloroplast chaperones including BSD2.Science2017
28803776Mechanism of Enzyme Repair by the AAA<sup>+</sup> Chaperone Rubisco Activase.Mol Cell2017
26727489Structure of human heat-shock transcription factor 1 in complex with DNA.Nat Struct Mol Biol2016
26422689The GroEL-GroES Chaperonin Machine: A Nano-Cage for Protein Folding.Trends Biochem Sci2016
26954324Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51.J Med Chem2016
25487014GrpE, Hsp110/Grp170, HspBP1/Sil1 and BAG domain proteins: nucleotide exchange factors for Hsp70 molecular chaperones.Subcell Biochem2015
26305355Structural Analysis of the Rubisco-Assembly Chaperone RbcX-II from Chlamydomonas reinhardtii.PLoS One2015
26419422Structure-Affinity Relationship Analysis of Selective FKBP51 Ligands.J Med Chem2015
27246049Degradation of potent Rubisco inhibitor by selective sugar phosphatase.Nat Plants2015
26913285The nucleotide exchange factors of Hsp70 molecular chaperones.Front Mol Biosci2015
26237510Structure and mechanism of the Rubisco-assembly chaperone Raf1.Nat Struct Mol Biol2015
25412894Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs).Angew Chem Int Ed Engl2015
25436518Selective inhibitors of the FK506-binding protein 51 by induced fit.Nat Chem Biol2015
23543331Maintaining photosynthetic CO2 fixation via protein remodelling: the Rubisco activases.Photosynth Res2014
25286062Stereoselective construction of the 5-hydroxy diazabicyclo[4.3.1]decane-2-one scaffold, a privileged motif for FK506-binding proteins.Org Lett2014
25200683A combined IR/IR and IR/UV spectroscopy study on the proton transfer coordinate of isolated 3-hydroxychromone in the electronic ground and excited state.Phys Chem Chem Phys2014
24813614GroEL/ES chaperonin modulates the mechanism and accelerates the rate of TIM-barrel domain folding.Cell2014
24516147Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11.Proc Natl Acad Sci U S A2014
24650728Thermostatted micro-reactor NMR probe head for monitoring fast reactions.J Magn Reson2014
22951723Epidermal growth factor facilitates melanoma lymph node metastasis by influencing tumor lymphangiogenesis.J Invest Dermatol2013
23933011Crystal structures of the free and ligand-bound FK1-FK2 domain segment of FKBP52 reveal a flexible inter-domain hinge.J Mol Biol2013
23647266Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control.J Med Chem2013
23746257Molecular chaperone functions in protein folding and proteostasis.Annu Rev Biochem2013
23812373Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle.Nat Struct Mol Biol2013
23190889A c-kit mutation in exon 18 in familial mastocytosis.J Invest Dermatol2013
23358420Large FK506-binding proteins shape the pharmacology of rapamycin.Mol Cell Biol2013
22187461The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together.Proc Natl Acad Sci U S A2012
23197838Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT.Proc Natl Acad Sci U S A2012
22984071Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry.Science2012
22503819The molecular architecture of the eukaryotic chaperonin TRiC/CCT.Structure2012
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Collaborators

Institute of Biochemistry, HUN-REN Biological Research Centre
Co-authored papers 7
Max Planck Institute of Biochemistry
Co-authored papers 5
Co-authored papers 4
Co-authored papers 4
Institute of Anatomy, University of Zurich
Co-authored papers 3
Max Planck Institute of Biochemistry
Co-authored papers 3
ETH Zurich
Co-authored papers 2
Institute of Biochemistry and Molecular Biology, Semmelweis University
Co-authored papers 2
Utrecht University
Co-authored papers 2
Max Planck Institute of Biochemistry
Co-authored papers 2
Institute for Computational Biology
Co-authored papers 2
Technical University Darmstadt
Co-authored papers 2
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 2
MicroBiopharm Japan Co. Ltd.
Co-authored papers 1
Co-authored papers 1
University of Munich
Co-authored papers 1
Institute of Molecular Biology and Biophysics, ETH Zurich
Co-authored papers 1
Stanford University
Co-authored papers 1
Institute of Virology, Philipps University Marburg
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
University of Zurich
Co-authored papers 1
Co-authored papers 1
Max Planck Institute of Biochemistry
Co-authored papers 1
Max-Planck Institute of Biochemistry
Co-authored papers 1
University of Cambridge
Co-authored papers 1
University of Alabama at Birmingham
Co-authored papers 1
Max Planck Institute of Biophysics
Co-authored papers 1
National Institute of Advanced Industrial Science and Technology (AIST)
Co-authored papers 1
Medical Center, University of Freiburg
Co-authored papers 1
University of Cambridge
Co-authored papers 1