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Author Details

Brigita Lenarcic
University of Ljubljana
1985
73
32
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33844684Molecular basis of F-actin regulation and sarcomere assembly via myotilin.PLoS Biol2021
32486423Current View on EpCAM Structural Biology.Cells2020
33321927The Central Region of Testican-2 Forms a Compact Core and Promotes Cell Migration.Int J Mol Sci2020
30703555The catalytic domain of cathepsin C (dipeptidyl-peptidase I) alone is a fully functional endoprotease.Protein Expr Purif2019
33855476The Carboxypeptidase Activity of Cathepsin X is not Controlled by Endogenous Inhibitors.Acta Chim Slov2019
30261040EpCAM ectodomain EpEX is a ligand of EGFR that counteracts EGF-mediated epithelial-mesenchymal transition through modulation of phospho-ERK1/2 in head and neck cancers.PLoS Biol2018
30185875EpCAM homo-oligomerization is not the basis for its role in cell-cell adhesion.Sci Rep2018
28040478Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells.Biochim Biophys Acta Mol Cell Res2017
28638118Conformational plasticity and evolutionary analysis of the myotilin tandem Ig domains.Sci Rep2017
26166069Nicotiana benthamiana cathepsin B displays distinct enzymatic features which differ from its human relative and aleurain-like protease.Biochimie2016
27859061An allosteric site enables fine-tuning of cathepsin K by diverse effectors.FEBS Lett2016
27272015Structure and calcium-binding studies of calmodulin-like domain of human non-muscle α-actinin-1.Sci Rep2016
27246477The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity.Arch Biochem Biophys2016
26724312Cleavage and cell adhesion properties of human epithelial cell adhesion molecule (HEPCAM).J Biol Chem2016
25981199The cytosolic tail of the tumor marker protein Trop2--a structural switch triggered by phosphorylation.Sci Rep2015
26292218Cleavage and cell adhesion properties of human epithelial cell adhesion molecule (HEPCAM).J Biol Chem2015
26306868Human cathepsin L, a papain-like collagenase without proline specificity.FEBS J2015
24518821A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods.Nat Commun2014
25587532Cysteine cathepsin activity regulation by glycosaminoglycans.Biomed Res Int2014
25163760Crystal structure and its bearing towards an understanding of key biological functions of EpCAM.Nat Commun2014
25184245Probing the activity modification space of the cysteine peptidase cathepsin K with novel allosteric modifiers.PLoS One2014
23562595Identification of new peptide amides as selective cathepsin L inhibitors: the first step towards selective irreversible inhibitors?Bioorg Med Chem Lett2013
25436581Papain-like peptidases: structure, function, and evolution.Biomol Concepts2013
23872121Biochemical and preliminary X-ray characterization of the tumor-associated calcium signal transducer 2 (Trop2) ectodomain.Protein Expr Purif2013
23629523Cathepsin K: a unique collagenolytic cysteine peptidase.Biol Chem2013
23437253The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties.PLoS One2013
22100277A simple and efficient protocol for the production of recombinant cathepsin V and other cysteine cathepsins in soluble form in Escherichia coli.Protein Expr Purif2012
23125066A novel photoaffinity-based probe for selective detection of cathepsin L active form.Chembiochem2012
22569264Clusterin is a specific stabilizer and liberator of extracellular cathepsin K.FEBS Lett2012
22102232Expression, crystallization and preliminary X-ray characterization of the human epithelial cell-adhesion molecule ectodomain.Acta Crystallogr Sect F Struct Biol Cryst Commun2011
20450492Conformational flexibility and allosteric regulation of cathepsin K.Biochem J2010
17950619Purification and characterization of a recombinant human testican-2 expressed in baculovirus-infected Sf9 insect cells.Protein Expr Purif2008
18713022Cytotoxic and peptidase inhibitory activities of selected non-hepatotoxic cyclic peptides from cyanobacteria.Biol Chem2008
18708147Recombinant human SMOCs produced by in vitro refolding: calcium-binding properties and interactions with serum proteins.Protein Expr Purif2008
17227755Interaction between human cathepsins K, L, and S and elastins: mechanism of elastinolysis and inhibition by macromolecular inhibitors.J Biol Chem2007
16368776Diversity and evolution of the thyroglobulin type-1 domain superfamily.Mol Biol Evol2006
15843150Dual concentration-dependent activity of thyroglobulin type-1 domain of testican: specific inhibitor and substrate of cathepsin L.Biol Chem2005
12727298Effects of proteinase inhibitors on digestive proteinases and growth of the red flour beetle, Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae).Comp Biochem Physiol C Toxicol Pharmacol2003
12650938Structural characterization of thyroglobulin type-1 domains of equistatin.FEBS Lett2003
10748022Saxiphilin, a saxitoxin-binding protein with two thyroglobulin type 1 domains, is an inhibitor of papain-like cysteine proteinases.J Biol Chem2000
10722055Cloning and expression of functional equistatin.Biol Chem2000
10720485Equistatin, a protease inhibitor from the sea anemone actinia equina, is composed of three structural and functional domains.Biochem Biophys Res Commun2000
10092883Acidic pH as a physiological regulator of human cathepsin L activity.Eur J Biochem1999
10384966Cathepsin S and cruzipain are inhibited by equistatin from Actinia equina.Biol Chem1999
9872988Thyroglobulin type-1 domains in equistatin inhibit both papain-like cysteine proteinases and cathepsin D.J Biol Chem1999
9753766The cysteine protease activity of Colorado potato beetle (Leptinotarsa decemlineata Say) guts, which is insensitive to potato protease inhibitors, is inhibited by thyroglobulin type-1 domain inhibitors.Insect Biochem Mol Biol1998
9524061Thyropins--new structurally related proteinase inhibitors.Biol Chem1998
9153250Equistatin, a new inhibitor of cysteine proteinases from Actinia equina, is structurally related to thyroglobulin type-1 domain.J Biol Chem1997
8706679Purification and structural characterization of bovine cathelicidins, precursors of antimicrobial peptides.Eur J Biochem1996
8898076Differences in specificity for the interactions of stefins A, B and D with cysteine proteinases.FEBS Lett1996
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Collaborators

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Co-authored papers 38
University of Ljubljana
Co-authored papers 16
J. Stefan Institute
Co-authored papers 4
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Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
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