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Author Details

Juha Saharinen
1994
38
28
PMIDPaper TitleJournal TitlePublished Year
21544814Candidate driver genes in microsatellite-unstable colorectal cancer.International Journal of Cancer2012
22479202Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.PLoS Genet2012
22783900Inter-tissue networks between the basal forebrain, hippocampus, and prefrontal cortex in a model for depression caused by disturbed sleep.Journal of Neurogenetics2012
20551151Mutations in the circadian gene CLOCK in colorectal cancer.Molecular Cancer Research2010
20686565Biological, clinical and population relevance of 95 loci for blood lipids.Nature2010
20384783Gene expression patterns in a rodent model for depression.European Journal of Neuroscience2010
19060911Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.Nat Genet2009
19431147Modulation of TGF-beta activity by latent TGF-beta-binding protein 1 in human malignant glioma cells.Int J Cancer2009
18371231Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases.BMC Genomics2008
19061986The genome-wide patterns of variation expose significant substructure in a founder population.Am J Hum Genet2008
19014429Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients.BMC Medical Genomics2008
17932056CanGEM: mining gene copy number changes in cancer.Nucleic Acids Research2008
18391202Unregulated smooth-muscle myosin in human intestinal neoplasia.Proc Natl Acad Sci U S A2008
18336063Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity.PLoS Med2008
18083234Functional interaction of AIRE with PIAS1 in transcriptional regulation.Molecular Immunology2008
18600308Critical immunological pathways are downregulated in APECED patient dendritic cells.Journal of Molecular Medicine2008
18455124Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype.Cancer Cell2008
17234577Transcriptomal comparison of human dermal lymphatic endothelial cells ex vivo and in vitro.Physiol Genomics2007
17443787Neural precursor cells from a fatal human motoneuron disease differentiate despite aberrant gene expression.Developmental Neurobiology2007
17297452Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.Oncogene2007
17530208Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response.Journal of Molecular Medicine2007
16424004Profiling genetic variation along the androgen biosynthesis and metabolism pathways implicates several single nucleotide polymorphisms and their combinations as prostate cancer risk factors.Cancer Res2006
16496002Identification of pathways regulating cell size and cell-cycle progression by RNAi.Nature2006
16135556Infantile onset spinocerebellar ataxia is caused by recessive mutations in mitochondrial proteins Twinkle and Twinky.Human Molecular Genetics2005
16155903Indicative oligodendrocyte dysfunction in spinal cords of human fetuses suffering from a lethal motoneuron disease.2005
12154076Secretion of human latent TGF-beta-binding protein-3 (LTBP-3) is dependent on co-expression of TGF-beta.Journal of Cell Science2002
12459258cDNA cloning, expression profile and genomic structure of a novel human transcript on chromosome 10q24, and its analyses as a candidate gene for infantile onset spinocerebellar ataxia.Gene2002
11170294Latency, activation, and binding proteins of TGF-beta.Microscopy Research and Technique2001
11683420Novel non-TGF-beta-binding splice variant of LTBP-4 in human cells and tissues provides means to decrease TGF-beta deposition.Journal of Cell Science2001
10646116Role of the latent transforming growth factor beta binding protein 1 in fibrillin-containing microfibrils in bone cells in vitro and in vivo.J Bone Miner Res2000
10930463Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.Molecular Biology of the Cell2000
10551816Independent promoters regulate the expression of two amino terminally distinct forms of latent transforming growth factor-beta binding protein-1 (LTBP-1) in a cell type-specific manner.Journal of Biological Chemistry1999
10743502Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action.Cytokine and Growth Factor Reviews1999
9709808Extracellular matrix-associated transforming growth factor-beta: role in cancer cell growth and invasion.Advances in Cancer Research1998
9660815Identification and characterization of a new latent transforming growth factor-beta-binding protein, LTBP-4.Journal of Biological Chemistry1998
8617200Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1.EMBO Journal1996
8756760Latent transforming growth factor-beta 1 and its binding protein are components of extracellular matrix microfibrils.Journal of Histochemistry and Cytochemistry1996
7507203Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase.Mol Cell Biol1994
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Wihuri Research Institute
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King's College London
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