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Author Details

Alan Rick Horwitz
Allen Institute for Cell Science
1977
188
82
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36599983Integrated intracellular organization and its variations in human iPS cells.Nature2023
37535733The new cell theory<b>The Master Builder</b> <i>Alfonso Martinez Arias</i> Basic Books, 2023, 352 pp.Science2023
35063094The new era of quantitative cell imaging-challenges and opportunities.Mol Cell2022
34845353It's time to incorporate diversity into our basic science and disease models.Nat Cell Biol2021
33783351Pre-complexation of talin and vinculin without tension is required for efficient nascent adhesion maturation.Elife2021
28477140Chondroitin Sulfate Impairs Neural Stem Cell Migration Through ROCK Activation.Mol Neurobiol2018
28679638Actin-Based Adhesion Modules Mediate Cell Interactions with the Extracellular Matrix and Neighboring Cells.Cold Spring Harb Perspect Biol2017
28114311RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development.PLoS One2017
28437464Inhibition of αvβ3 integrin induces loss of cell directionality of oral squamous carcinoma cells (OSCC).PLoS One2017
29085052Contact guidance persists under myosin inhibition due to the local alignment of adhesions and individual protrusions.Sci Rep2017
28814507Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization.Mol Biol Cell2017
28546174Whole cell maps chart a course for 21st-century cell biology.Science2017
27109104Breast cancer antiestrogen resistance 3-p130<sup>Cas</sup> interactions promote adhesion disassembly and invasion in breast cancer cells.Oncogene2016
26361333Integrated, multi-scale, spatial-temporal cell biology--A next step in the post genomic era.Methods2016
27637343Interdisciplinary Team Science in Cell Biology.Trends Cell Biol2016
26958871Cellular Biophysics.Biophys J2016
26978651Fibronectin Modulates Cell Adhesion and Signaling to Promote Single Cell Migration of Highly Invasive Oral Squamous Cell Carcinoma.PLoS One2016
25484346An open data ecosystem for cell migration research.Trends Cell Biol2015
26542704Non-muscle myosin II in disease: mechanisms and therapeutic opportunities.Dis Model Mech2015
26585507Sperm Associated Antigen 6 (SPAG6) Regulates Fibroblast Cell Growth, Morphology, Migration and Ciliogenesis.Sci Rep2015
26419705A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration.Nat Commun2015
26238352Signaling networks that regulate cell migration.Cold Spring Harb Perspect Biol2015
26169356ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity.J Cell Biol2015
25869664A regulatory motif in nonmuscle myosin II-B regulates its role in migratory front-back polarity.J Cell Biol2015
25698931Involvement of calpains in adult neurogenesis: implications for stroke.Front Cell Neurosci2015
25733709Rick Horwitz: words do not suffice.J Cell Biol2015
25170137Cell Biology. Many modes of motility.Science2014
25007055α-Actinin-2 mediates spine morphology and assembly of the post-synaptic density in hippocampal neurons.PLoS One2014
25088556Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions.Curr Biol2014
23280111Fluorescence fluctuation approaches to the study of adhesion and signaling.Methods Enzymol2013
24223019A nu-space for ICS: characterization and application to measure protein transport in live cells.New J Phys2013
23932405Matrix microarchitecture and myosin II determine adhesion in 3D matrices.Curr Biol2013
23264468CD81 regulates cell migration through its association with Rac GTPase.Mol Biol Cell2013
22196929The structure of cell-matrix adhesions: the new frontier.Curr Opin Cell Biol2012
23083710STICCS reveals matrix-dependent adhesion slipping and gripping in migrating cells.Biophys J2012
23151664The origins of the molecular era of adhesion research.Nat Rev Mol Cell Biol2012
22792239The integrin-ligand interaction regulates adhesion and migration through a molecular clutch.PLoS One2012
22496808Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics.PLoS One2012
21281572Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions.Biophys J2011
22194302Adhesion dynamics at a glance.J Cell Sci2011
21826213High glucose-mediated oxidative stress impairs cell migration.PLoS One2011
21820627Cell migration: PKA and RhoA set the pace.Curr Biol2011
21887379Myosin IIb activity and phosphorylation status determines dendritic spine and post-synaptic density morphology.PLoS One2011
21885598Integrins in cell migration.Cold Spring Harb Perspect Biol2011
21748665Cell migration: an overview.Methods Mol Biol2011
21482721Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells.J Cell Biol2011
21173800Reducing background fluorescence reveals adhesions in 3D matrices.Nat Cell Biol2011
20195494Stochastic model of integrin-mediated signaling and adhesion dynamics at the leading edges of migrating cells.PLoS Comput Biol2010
20729930Cell adhesion: integrating cytoskeletal dynamics and cellular tension.Nat Rev Mol Cell Biol2010
20971064Myosin light chain mono- and di-phosphorylation differentially regulate adhesion and polarity in migrating cells.Biochem Biophys Res Commun2010
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Collaborators

Donna J Webb
Vanderbilt University
Co-authored papers 21
Leanna Whitmore
University of Virginia School of Medicine
Co-authored papers 15
Douglas A Lauffenburger
Massachusetts Institute of Technology
Co-authored papers 13
Claire M Brown
Co-authored papers 9
John T Parsons
The School of Medicine, University of Virginia
Co-authored papers 8
Marcelo Lazzaron Lamers
Institute of Basic Health Sciences, Federal University of Rio Grande do Sul (UFRGS)
Co-authored papers 6
Mark H Ginsberg
University of California
Co-authored papers 5
Donald F Hunt
University of Virginia
Co-authored papers 5
Jeffrey Shabanowitz
University of Virginia
Co-authored papers 5
Mykola Kovalenko
Co-authored papers 4
Melanie J Schroeder
University of Virginia
Co-authored papers 3
Ri-Ichiroh Manabe
Center for Integrative Medical Sciences
Co-authored papers 3
Mark W Mayhew
University of Virginia
Co-authored papers 3
Erin D Jeffery
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
Co-authored papers 2
Susanne M Rafelski
Co-authored papers 2
Jay W Fox
University of Virginia
Co-authored papers 2
Kristina Nelson
Virginia Commonwealth University
Co-authored papers 1
Susanna-Assunta Sansone
Oxford e-Research Centre, University of Oxford
Co-authored papers 1
Stephen J P Pratt
University of Maryland School of Medicine
Co-authored papers 1
Paola Masuzzo
Co-authored papers 1
Nicholas E Sherman
University of Virginia
Co-authored papers 1
Josh Moore
University of Dundee
Co-authored papers 1
Robert F Murphy
Carnegie Mellon University
Co-authored papers 1
Sylvia E Le Dévédec
Co-authored papers 1
Joy M Polefrone
Co-authored papers 1
Theo A Knijnenburg
Allen Institute for Cell Science
Co-authored papers 1
Mark H Ellisman
National Center for Microscopy and Imaging Research, University of California
Co-authored papers 1
Neda Bagheri
University of Washington
Co-authored papers 1
Tony Hunter
Salk Institute for Biological Studies
Co-authored papers 1
Anne E Carpenter
Broad Institute of MIT and Harvard
Co-authored papers 1
Release 1.2