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Author Details

Beverley Shields
2003
58
33
PMIDPaper TitleJournal TitlePublished Year
37328784Comparison of causal forest and regression-based approaches to evaluate treatment effect heterogeneity: an application for type 2 diabetes precision medicine.BMC Med Inform Decis Mak2023
36191079Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: a Mendelian randomization study.Int J Epidemiol2023
35061023Improvements in Awareness and Testing Have Led to a Threefold Increase Over 10 Years in the Identification of Monogenic Diabetes in the U.K.Diabetes Care2022
34618178Association of birthweight and penetrance of diabetes in individuals with HNF4A-MODY: a cohort study.Diabetologia2022
35226681Alternative pre-analytic sample handling techniques for glucose measurement in the absence of fluoride tubes in low resource settings.PLoS ONE2022
34016577Associations between low HDL, sex and cardiovascular risk markers are substantially different in sub-Saharan Africa and the UK: analysis of four population studies.BMJ Global Health2021
32702468Predicting post one-year durability of glucose-lowering monotherapies in patients with newly-diagnosed type 2 diabetes mellitus - A MASTERMIND precision medicine approach (UKPDS 87).Diabetes Research and Clinical Practice2020
32194148Prior event rate ratio adjustment produced estimates consistent with randomized trial: a diabetes case study.Journal of Clinical Epidemiology2020
32193268Strategies to identify individuals with monogenic diabetes: results of an economic evaluation.BMJ Open2020
33371044TriMaster: randomised double-blind crossover study of a DPP4 inhibitor, SGLT2 inhibitor and thiazolidinedione as second-line or third-line therapy in patients with type 2 diabetes who have suboptimal glycaemic control on metformin treatment with or withouBMJ Open2020
31439274Clusters provide a better holistic view of type 2 diabetes than simple clinical features - Authors' reply.Lancet Diabetes and Endocrinology,The2019
30969375Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes.Diabetologia2019
31047901Disease progression and treatment response in data-driven subgroups of type 2 diabetes compared with models based on simple clinical features: an analysis using clinical trial data.Lancet Diabetes and Endocrinology,The2019
30828962Time trends in prescribing of type 2 diabetes drugs, glycaemic response and risk factors: A retrospective analysis of primary care data, 2010-2017.Diabetes, Obesity and Metabolism2019
26681714Adherence to Oral Glucose-Lowering Therapies and Associations With 1-Year HbA1c: A Retrospective Cohort Analysis in a Large Primary Care Database.Diabetes Care2016
27435864South Asian individuals with diabetes who are referred for MODY testing in the UK have a lower mutation pick-up rate than white European people.Diabetologia2016
27271189Systematic Population Screening, Using Biomarkers and Genetic Testing, Identifies 2.5% of the U.K. Pediatric Diabetes Population With Monogenic Diabetes.Diabetes Care2016
26577414A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults.Diabetes Care2016
26022541Assessment of the HNF1B Score as a Tool to Select Patients for HNF1B Genetic Testing.Nephron2015
26106223Recognition and Management of Individuals With Hyperglycemia Because of a Heterozygous Glucokinase Mutation.Diabetes Care2015
24092492Cross-sectional and longitudinal studies suggest pharmacological treatment used in patients with glucokinase mutations does not alter glycaemia.Diabetologia2014
25261570Factors determining penetrance in familial atypical haemolytic uraemic syndrome.J Med Genet2014
23264298Response to Comment on: Chakera et al. Antenatal diagnosis of fetal genotype determines if maternal hyperglycemia due to a glucokinase mutation requires treatment. Diabetes Care 2012;35:1832-1834.Diabetes Care2013
22238593A genome-wide association search for type 2 diabetes genes in African Americans.PLoS One2012
22479202Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.PLoS Genet2012
21317282A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement.Eur J Endocrinol2011
21282362Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.Diabetes2011
19997936Ischemic conditioning shows a time-dependant influence on the fate of the gastric conduit after minimally invasive esophagectomy.Surgical Endoscopy and Other Interventional Techniques2010
19794065Polygenic risk variants for type 2 diabetes susceptibility modify age at diagnosis in monogenic HNF1A diabetes.Diabetes2010
20081858New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.Nat Genet2010
19933169Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.Hum Mol Genet2010
19228808Type 2 diabetes risk alleles are associated with reduced size at birth.Diabetes2009
19405871Semi-automated unidirectional sequence analysis for mutation detection in a clinical diagnostic setting.Genet Test Mol Biomarkers2009
19429911A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.Hum Mol Genet2009
19017761Cigarette smoking during pregnancy is associated with alterations in maternal and fetal thyroid function.Journal of Clinical Endocrinology and Metabolism2009
18162506Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood.Diabetes2008
18346983Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.Diabetes2008
18372903Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.Nat Genet2008
18492748A common variation in deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triiodothyronine.J Clin Endocrinol Metab2008
18356407The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of HNF4A isoforms from the P1 promoter during fetal development.Diabetes2008
17032713Detection of thyroid dysfunction in early pregnancy: Universal screening or targeted high-risk case finding?Journal of Clinical Endocrinology and Metabolism2007
17463249Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.Science2007
17503332Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals.Am J Hum Genet2007
17767157A common variant of HMGA2 is associated with adult and childhood height in the general population.Nat Genet2007
17725629The transcription factor 7-like 2 (TCF7L2) gene is associated with Type 2 diabetes in UK community-based cases, but the risk allele frequency is reduced compared with UK cases selected for genetic studies.Diabetic Medicine2007
17434869A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.Science2007
17125497A study of association between common variation in the growth hormone-chorionic somatomammotropin hormone gene cluster and adult fasting insulin in a UK Caucasian population.Journal of Negative Results in BioMedicine2006
17186458A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses.Am J Hum Genet2006
17020404Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.PLoS Medicine2006
17065358No evidence of association of ENPP1 variants with type 2 diabetes or obesity in a study of 8,089 U.K. Caucasians.Diabetes2006
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