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Author Details

Martin Hirst
University of British Columbia
1998
167
72
PMIDPaper TitleJournal TitlePublished Year
36657718SMARCB1 Loss in Poorly Differentiated Chordomas Drives Tumor Progression.Am J Pathol2023
37503119The ENCODE Uniform Analysis Pipelines.Res Sq2023
37213235RUNX1 colludes with NOTCH1 to reprogram chromatin in T cell acute lymphoblastic leukemia.iScience2023
37066421The ENCODE Uniform Analysis Pipelines.bioRxiv2023
34294889De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer.Cell Death Differ2022
35787786Genome-wide detection of imprinted differentially methylated regions using nanopore sequencing.Elife2022
35818933A novel methylated cell-free DNA marker panel to monitor treatment response in metastatic prostate cancer.Epigenomics2022
35624144Elucidating the importance and regulation of key enhancers for human MEIS1 expression.Leukemia2022
36351924Single-cell profiling reveals a memory B cell-like subtype of follicular lymphoma with increased transformation risk.Nat Commun2022
34588613Stress hematopoiesis induces a proliferative advantage in TET2 deficiency.Leukemia2022
34687784Optimization of magnetic bead-based nucleic acid extraction for SARS-CoV-2 testing using readily available reagents.J Virol Methods2022
32499242Epigenetic and functional changes imposed by NUP98-HOXA9 in a genetically engineered model of chronic myeloid leukemia progression.Haematologica2021
33758253Distinct DNA methylation patterns associated with treatment resistance in metastatic castration resistant prostate cancer.Sci Rep2021
33618748Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase.Genome Biol2021
33891899Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease.Dev Cell2021
33659009Butyrate Shapes Immune Cell Fate and Function in Allergic Asthma.Front Immunol2021
34931022Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury.NPJ Precis Oncol2021
34806017CRIS: complete reconstruction of immunoglobulin <i>V-D-J</i> sequences from RNA-seq data.Bioinform Adv2021
34828381Prenatal Adversity Alters the Epigenetic Profile of the Prefrontal Cortex: Sexually Dimorphic Effects of Prenatal Alcohol Exposure and Food-Related Stress.Genes (Basel)2021
34149808A Scalable Strand-Specific Protocol Enabling Full-Length Total RNA Sequencing From Single Cells.Front Genet2021
33443552Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma.Blood2021
32384151Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice.Blood2020
31772328Initiation of human mammary cell tumorigenesis by mutant KRAS requires YAP inactivation.Oncogene2020
33301029MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus.Blood2020
32677466Epigenomic programming in early fetal brain development.Epigenomics2020
32867540Dynamics of the cell-free DNA methylome of metastatic prostate cancer during androgen-targeting treatment.Epigenomics2020
32641414The Pathognomonic FOXL2 C134W Mutation Alters DNA-Binding Specificity.Cancer Res2020
30572802Clonal Analysis of Mouse Mammary Luminal Epithelial Cell Transplants.Stem Cells Dev2019
31604797Histone Chaperone Paralogs Have Redundant, Cooperative, and Divergent Functions in Yeast.Genetics2019
31601272MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2.Epigenetics Chromatin2019
30970253Autophagy Regulation of Metabolism Is Required for CD8<sup>+</sup> T Cell Anti-tumor Immunity.Cell Rep2019
30933372Hepatocyte Nuclear Factor 4-Alpha Is Essential for the Active Epigenetic State at Enhancers in Mouse Liver.Hepatology2019
28663574Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia.Leukemia2018
30078558High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations.Stem Cell Reports2018
29802403Single-cell analysis identifies a CD33<sup>+</sup> subset of human cord blood cells with high regenerative potential.Nat Cell Biol2018
30269902Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity.Cell Stem Cell2018
30568673Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues.Front Genet2018
29361176The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability.Nucleic Acids Res2018
29733873RUNX1 promotes cell growth in human T-cell acute lymphoblastic leukemia by transcriptional regulation of key target genes.Exp Hematol2018
29217774Micro-ribonucleic acid-155 is a direct target of Meis1, but not a driver in acute myeloid leukemia.Haematologica2018
28602946Whole-genome analysis reveals unexpected dynamics of mutant subclone development in a patient with JAK2-V617F-positive chronic myeloid leukemia.Exp Hematol2017
28360175Draft Genome Sequence of the Pelagic Photoferrotroph <i>Chlorobium phaeoferrooxidans</i>.Genome Announc2017
28327288Atrophin controls developmental signaling pathways via interactions with Trithorax-like.Elife2017
29286469Generation of Native Chromatin Immunoprecipitation Sequencing Libraries for Nucleosome Density Analysis.J Vis Exp2017
28814753The [PSI <sup>+</sup>] yeast prion does not wildly affect proteome composition whereas selective pressure exerted on [PSI <sup>+</sup>] cells can promote aneuploidy.Sci Rep2017
28679365Increasing quality, throughput and speed of sample preparation for strand-specific messenger RNA sequencing.BMC Genomics2017
28706564Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem cells via Kdm3a/b.Epigenetics Chromatin2017
28570594Automated high throughput nucleic acid purification from formalin-fixed paraffin-embedded tissue samples for next generation sequence analysis.PLoS One2017
28808080Characterization of the human thyroid epigenome.J Endocrinol2017
28854171Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.Nature2017
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Collaborators

Marco A Marra
University of British Columbia
Co-authored papers 92
Steven J M Jones
University of British Columbia
Co-authored papers 64
Yongjun Zhao
Canada British Columbia Cancer Research Centre, University of British Columbia
Co-authored papers 46
Richard A Moore
Co-authored papers 31
Ryan D Morin
Simon Fraser University
Co-authored papers 24
Samuel Aparicio
University of British Columbia
Co-authored papers 22
Andrew J Mungall
Co-authored papers 22
Angela Tam
Co-authored papers 21
Sohrab P Shah
Memorial Sloan Kettering Cancer Center
Co-authored papers 19
Joseph F Costello
University of California san francisco
Co-authored papers 17
Robert A Holt
BC Cancer Research Institute
Co-authored papers 16
Nina Thiessen
Co-authored papers 15
Amy G Robertson
Present address: Dxige Research Inc.
Co-authored papers 14
Alireza Heravi-Moussavi
Ferdowsi University of Mashhad
Co-authored papers 14
Malachi Griffith
Washington University
Co-authored papers 13
Ting Wang
Washington University School of Medicine
Co-authored papers 13
David G Huntsman
University of British Columbia
Co-authored papers 13
Jacqueline E Schein
Canada British Columbia Cancer Research Centre, University of British Columbia
Co-authored papers 11
Peggy J Farnham
Keck School of Medicine of USC
Co-authored papers 11
Janine Senz
University of British Columbia
Co-authored papers 10
Leah M Prentice
British Columbia Women's Hospital and Health Centre
Co-authored papers 8
Eric Chuah
Co-authored papers 8
Yaron S Butterfield
Brain Tumour Foundation of Canada
Co-authored papers 8
Noreen Dhalla
Co-authored papers 7
Trevor J Pugh
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 7
Ivan Sadowski
University of British Columbia
Co-authored papers 7
Cyril B Gilks
University of British Columbia
Co-authored papers 6
Martin Krzywinski
BC Cancer Research Center
Co-authored papers 6
Ali Bashashati
University of British Columbia
Co-authored papers 6
Adrian Ally
Co-authored papers 6
Release 1.2