Author details

Full Name

Zhenghe Wang

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34826721	Genomic history and forensic characteristics of Sherpa highlanders on the Tibetan Plateau inferred from high-resolution InDel panel and genome-wide SNPs.		2022
35418124	Nuclear translocation of p85Î² promotes tumorigenesis of PIK3CA helical domain mutant cancer.	Nat Commun	2022
37397533	PD-L1 expression is regulated by ATP-binding of the ERBB3 pseudokinase domain.	Genes Dis	2022
35276002	Liver Endothelium Promotes HER3-Mediated Cell Survival in Colorectal Cancer with Wild-Type and Mutant KRAS.	Molecular Cancer Research	2022
33391422	NKCC1 promotes proliferation, invasion and migration in human gastric cancer cells via activation of the MAPK-JNK/EMT signaling pathway.	Journal of Cancer	2021
33456536	HBV induces liver fibrosis via the TGF-Î²1/miR-21-5p pathway.	Experimental and Therapeutic Medicine (discontinued)	2021
33172606	IDO-inhibitor potentiated immunogenic chemotherapy abolishes primary tumor growth and eradicates metastatic lesions by targeting distinct compartments within tumor microenvironment.	Biomaterials	2021
31448663	Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial-mesenchymal transition and subcellular re-localization of Beta-Catenin.	Epigenetics	2020
32082999	BAG2 Promotes Proliferation and Metastasis of Gastric Cancer via ERK1/2 Signaling and Partially Regulated by miR186.	Frontiers in Oncology	2020
32064346	Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity.	Sci Adv	2020
33464873	Correction to "Alginate Enhances Memory Properties of Antitumor CD8 T Cells by Promoting Cellular Antioxidation".	ACS Biomaterials Science and Engineering	2020
33042274	Noninvasive assessment and therapeutic monitoring of drug-resistant colorectal cancer by MR molecular imaging of extradomain-B fibronectin.	Theranostics	2020
32924985	FOXD3-AS1 suppresses the progression of non-small cell lung cancer by regulating miR-150/SRCIN1axis.	Cancer Biomarkers	2020
32959645	A Sequentially Responsive Nanosystem Breaches Cascaded Bio-barriers and Suppresses P-Glycoprotein Function for Reversing Cancer Drug Resistance.	ACS applied materials & interfaces	2020
32907836	5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against <i>PIK3CA</i>-Mutant Colorectal Cancers.	Cancer Res	2020
33004309	A facile and sensitive method of quantifying glutaminase binding to its inhibitor CB-839 in tissues.	J Genet Genomics	2020
31150989	STAT3-induced long noncoding RNA LINC00668 promotes migration and invasion of non-small cell lung cancer via the miR-193a/KLF7 axis.		2019
31844152	Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo.	Sci Rep	2019
31681267	Tissue-Resident Macrophages Limit Pulmonary CD8 Resident Memory T Cell Establishment.	Frontiers in Immunology	2019
31782506	miR-125 inhibits colorectal cancer proliferation and invasion by targeting TAZ.	Bioscience Reports	2019
31572976	Endothelial TGF-Î² signalling drives vascular inflammation and atherosclerosis.	Nat Metab	2019
31278009	Mutations in TP53, ZNF750, and RB1 typify ocular sebaceous carcinoma.	J Genet Genomics	2019
29747501	Multiproteomic and Transcriptomic Analysis of Oncogenic Î²-Catenin Molecular Networks.	Journal of Proteome Research	2018
30199013	Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay.	J Vis Exp	2018
27447856	Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis.	Oncotarget	2017
29138025	Novel all-hydrocarbon stapled p110Î±[E545K] peptides as blockers of the oncogenic p110Î±[E545K]-IRS1 interaction.	Bioorganic and Medicinal Chemistry Letters	2017
29070673	IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis.	Journal of Immunology	2017
27582379	Adverse Clinical Outcome Associated With Mutations That Typify African American Colorectal Cancers.	J Natl Cancer Inst	2016
30258894	Targeting glutamine metabolism in mutant colorectal cancers.	Genes and Diseases	2016
27321283	Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.	Nat Commun	2016
27267892	STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma.	Cancer Prev Res (Phila)	2016
26325016	How do oncoprotein mutations rewire protein-protein interaction networks?	Expert Review of Proteomics	2015
25753001	A Protein Interaction between Î²-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells.	Molecular Cancer Research	2015
25583493	Novel recurrently mutated genes in African American colon cancers.	Proc Natl Acad Sci U S A	2015
25263441	Genetic alterations of protein tyrosine phosphatases in human cancers.	Oncogene	2015
25941411	Reply to Ashktorab et al.: Mutational landscape of colon cancers in African Americans.	Proc Natl Acad Sci U S A	2015
26437221	Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival.	Oncotarget	2015
26307088	DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer.	Human Molecular Genetics	2015
26081291	Novel thiourea-based sirtuin inhibitory warheads.	Bioorganic and Medicinal Chemistry Letters	2015
26068857	TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration.	Science	2015
25129063	Discovery of common sequences absent in the human reference genome using pooled samples from next generation sequencing.	BMC Genomics	2014
25621300	Cancer driver candidate genes AVL9, DENND5A and NUPL1 contribute to MDCK cystogenesis.	Oncoscience	2014
24395800	Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer.	Proc Natl Acad Sci U S A	2014
24201312	Integrated analysis of the Wnt responsive proteome in human cells reveals diverse and cell-type specific networks.	Molecular BioSystems	2014
24389641	Regulation of protein stability of DNA methyltransferase 1 by post-translational modifications.	Acta Biochimica et Biophysica Sinica	2014
24196441	CtIP is required for DNA damage-dependent induction of P21.	Cell Cycle	2014
24378417	Phase II trial of imatinib in AIDS-associated Kaposi's sarcoma: AIDS Malignancy Consortium Protocol 042.	Journal of Clinical Oncology	2014
24178578	Targeting the protein-protein interaction between IRS1 and mutant p110Î± for cancer therapy.	Toxicologic Pathology	2014
24949727	PTPRT regulates high-fat diet-induced obesity and insulin resistance.	PLoS One	2014
23653350	Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway.	Journal of Biological Chemistry	2013