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Author Details

Malachi Griffith
Washington University
2003
134
53
PMIDPaper TitleJournal TitlePublished Year
37953380DGIdb 5.0: rebuilding the drug-gene interaction database for precision medicine and drug discovery platforms.Nucleic Acids Res2024
36251745Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma.Blood Adv2023
37910143Ultra-Deep Sequencing Reveals the Mutational Landscape of Classical Hodgkin Lymphoma.Cancer Res Commun2023
37487666Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment.J Immunother Cancer2023
37954974Normalization of drug and therapeutic concepts with Thera-Py.JAMIA Open2023
37824796Donor-Derived Follicular Lymphoma After Kidney Transplantation: A Case Report.JCO Precis Oncol2023
37493986Mutations associated with progression in follicular lymphoma predict inferior outcomes at diagnosis: Alliance A151303.Blood Adv2023
37810214Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer.iScience2023
36949070Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer.Nat Commun2023
37279078T-BET and EOMES sustain mature human NK cell identity and antitumor function.J Clin Invest2023
37034778Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer.bioRxiv2023
37027480Computational prediction of MHC anchor locations guides neoantigen identification and prioritization.Sci Immunol2023
36890230Neoantigen-targeted CD8<sup>+</sup> T cell responses with PD-1 blockade therapy.Nature2023
36373660CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase.Nucleic Acids Res2023
34780623Phase 1/dose expansion trial of brentuximab vedotin and lenalidomide in relapsed or refractory diffuse large B-cell lymphoma.Blood2022
35475554Large scale genotype- and phenotype-driven machine learning in Von Hippel-Lindau disease.Hum Mutat2022
35366592Standardized evidence-based approach for assessment of oncogenic and clinical significance of NTRK fusions.Cancer Genet2022
35494251Integrative genomic analysis reveals low T-cell infiltration as the primary feature of tobacco use in HPV-positive oropharyngeal cancer.iScience2022
35568002Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic livers.Cancer Genet2022
35624339A community approach to the cancer-variant-interpretation bottleneck.Nat Cancer2022
36617634Estimation of intrafamilial DNA contamination in family trio genome sequencing using deviation from Mendelian inheritance.Genome Res2022
36273232Personalized ctDNA micro-panels can monitor and predict clinical outcomes for patients with triple-negative breast cancer.Sci Rep2022
36063163Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
35101336Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
34871371Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant.Blood2022
35196021Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia.Sci Transl Med2022
34610950Characterization of the Genomic and Immunologic Diversity of Malignant Brain Tumors through Multisector Analysis.Cancer Discov2022
33237278Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts.Nucleic Acids Res2021
35611186<i>In silico</i> epitope prediction analyses highlight the potential for distracting antigen immunodominance with allogeneic cancer vaccines.Cancer Res Commun2021
33547198Yap1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas.Clin Cancer Res2021
33653917Genetic Ancestry Correlations with Driver Mutations Suggest Complex Interactions between Somatic and Germline Variation in Cancer.Cancer Discov2021
33556121Unraveling the chaotic genomic landscape of primary and metastatic canine appendicular osteosarcoma with current sequencing technologies and bioinformatic approaches.PLoS One2021
33832946Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma.Clin Cancer Res2021
35072136GA4GH: International policies and standards for data sharing across genomic research and healthcare.Cell Genom2021
35311178The GA4GH Variation Representation Specification: A computational framework for variation representation and federated identification.Cell Genom2021
34957471Sex- and mutation-specific p53 gain-of-function activity in gliomagenesis.Cancer Res Commun2021
34506690Exploring the Genomic Landscape of Cancer Patient Cohorts with GenVisR.Curr Protoc2021
34019588Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF.PLoS Pathog2021
34036230Impact of a 40-Gene Targeted Panel Test on Physician Decision Making for Patients With Acute Myeloid Leukemia.JCO Precis Oncol2021
34341766Bam-readcount - rapid generation of basepair-resolution sequence metrics.ArXiv2021
34173924Immunogenomic profiling and pathological response results from a clinical trial of docetaxel and carboplatin in triple-negative breast cancer.Breast Cancer Res Treat2021
34029233Multitarget Stool RNA Test for Noninvasive Detection of Colorectal Neoplasias in a Multicenter, Prospective, and Retrospective Cohort.Clin Transl Gastroenterol2021
33397681Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-unrelated Head and Neck Cancer: A Multicenter, Phase II Trial.Clin Cancer Res2021
32180547Wikidata as a knowledge graph for the life sciences.Elife2020
31907209pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens.Cancer Immunol Res2020
33040078Splicing factor SF3B1 promotes endometrial cancer progression via regulating KSR2 RNA maturation.Cell Death Dis2020
32665297Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial.Clin Cancer Res2020
32577507The clonal evolution of metastatic colorectal cancer.Sci Adv2020
32644817Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices.JCO Clin Cancer Inform2020
32610166Neoantigen prediction and computational perspectives towards clinical benefit: recommendations from the ESMO Precision Medicine Working Group.Ann Oncol2020
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Washington University
Co-authored papers 110
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The Ohio State University
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Co-authored papers 20
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Co-authored papers 19
The Ohio State University
Co-authored papers 19
University of British Columbia
Co-authored papers 18
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 18
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McDonnell Genome Institute, Washington University School of Medicine
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McDonnell Genome Institute, Washington University in St. Louis School of Medicine
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McDonnell Genome Institute, Washington University School of Medicine
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University of British Columbia
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