Skip to Main Content

Author Details

Steven M Opal
Infectious Disease Division at Brown University Warren Alpert Medical School
1979
317
77
PMIDPaper TitleJournal TitlePublished Year
36126289Antimicrobial Efficacy of Continuous Low-Irradiance Phototherapy Against Multidrug-Resistant Organisms.Photobiomodul Photomed Laser Surg2022
33858243A pilot study of an anti-endotoxin Ig-enriched bovine colostrum to prevent experimental sepsis.Innate Immun2021
33672437Therapeutic Rationale for Endotoxin Removal with Polymyxin B Immobilized Fiber Column (PMX) for Septic Shock.Int J Mol Sci2021
32198163Hiding in Plain Sight: an Approach to Treating Patients with Severe COVID-19 Infection.mBio2020
31733673Biomarkers of Infection and Sepsis.Crit Care Clin2020
33045189Steroids for sepsis and ARDS: this eternal controversy remains with COVID-19.Lancet2020
32690640Safety and Pharmacokinetics of Recombinant Human Plasma Gelsolin in Patients Hospitalized for Nonsevere Community-Acquired Pneumonia.Antimicrob Agents Chemother2020
32212525Activating Immunity to Fight a Foe - A New Path.N Engl J Med2020
32471831Reply to Siniorakis et al., "COVID-19 Interference with Renin-Angiotensin System in the Context of Heart Failure".mBio2020
31104069Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.JAMA2019
31585759Should we continue to test soluble thrombomodulin, or other systemic anticoagulants, as a life-saving therapy for sepsis-induced coagulopathy?Anaesth Crit Care Pain Med2019
31577035Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial.JAMA2019
31367740An Integrated Safety Summary of Omadacycline, a Novel Aminomethylcycline Antibiotic.Clin Infect Dis2019
30814582Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis.Sci Rep2019
30828456Physician agreement on the diagnosis of sepsis in the intensive care unit: estimation of concordance and analysis of underlying factors in a multicenter cohort.J Intensive Care2019
31028466Inter-α-inhibitor Ameliorates Endothelial Inflammation in Sepsis.Lung2019
31104070Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis.JAMA2019
28991823Mortality Benefit of Recombinant Human Interleukin-1 Receptor Antagonist for Sepsis Varies by Initial Interleukin-1 Receptor Antagonist Plasma Concentration.Crit Care Med2018
30126574Antibiotic Stewardship: Strategies to Minimize Antibiotic Resistance While Maximizing Antibiotic Effectiveness.Med Clin North Am2018
29875013Soluble programmed cell death protein-1 and programmed cell death ligand-1 in sepsis.Crit Care2018
30420852Coinfection With Influenza A Virus and <i>Klebsiella oxytoca</i>: An Underrecognized Impact on Host Resistance and Tolerance to Pulmonary Infections.Front Immunol2018
30409091Whatever happened to the Shwartzman phenomenon?Innate Immun2018
29581049Towards precision medicine in sepsis: a position paper from the European Society of Clinical Microbiology and Infectious Diseases.Clin Microbiol Infect2018
29388815Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial.Ann Am Thorac Soc2018
29632995Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).Intensive Care Med2018
29624409Validation of a Host Response Assay, SeptiCyte LAB, for Discriminating Sepsis from Systemic Inflammatory Response Syndrome in the ICU.Am J Respir Crit Care Med2018
28069650Evidence To Support Continuation of Statin Therapy in Patients with Staphylococcus aureus Bacteremia.Antimicrob Agents Chemother2017
28194511Should all septic patients be given systemic anticoagulation? No.Intensive Care Med2017
28130686Sepsis: frontiers in supportive care, organisation and research.Intensive Care Med2017
28159171Severe Pneumonia Caused by Legionella pneumophila: Differential Diagnosis and Therapeutic Considerations.Infect Dis Clin North Am2017
28396715Immunomodulatory oligonucleotide IMT504: Effects on mesenchymal stem cells as a first-in-class immunoprotective/immunoregenerative therapy.World J Stem Cells2017
29169402Age, exercise, and the outcome of sepsis.Crit Care2017
28910137The Role of S1PR3 in Protection from Bacterial Sepsis.Am J Respir Crit Care Med2017
27984280Source Control in Sepsis Urgent or Not So Fast?Crit Care Med2017
26974318PHARMACOLOGICAL SIRT1 ACTIVATION IMPROVES MORTALITY AND MARKEDLY ALTERS TRANSCRIPTIONAL PROFILES THAT ACCOMPANY EXPERIMENTAL SEPSIS.Shock2016
28117397Sepsis and septic shock.Nat Rev Dis Primers2016
26584195Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial.Crit Care Med2016
27978847Non-antibiotic treatments for bacterial diseases in an era of progressive antibiotic resistance.Crit Care2016
27713886The role of genetics and antibodies in sepsis.Ann Transl Med2016
26863125THE EPITHELIUM AS A TARGET IN SEPSIS.Shock2016
26992066Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials.Crit Care Med2016
26886007Isolating Influenza RNA from Clinical Samples Using Microfluidic Oil-Water Interfaces.PLoS One2016
27015977A novel approach for emerging and antibiotic resistant infections: Innate defense regulators as an agnostic therapy.J Biotechnol2016
26908575Reply to "Generic Statins and Angiotensin Receptor Blockers: Are They Really Useful in Ebola?".mBio2016
26903338The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).JAMA2016
26975243Immunosuppression and Secondary Infection in Sepsis: Part, Not All, of the Story.JAMA2016
25305323CD28 homodimer interface mimetic peptide acts as a preventive and therapeutic agent in models of severe bacterial sepsis and gram-negative bacterial peritonitis.J Infect Dis2015
26252194The Central Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Septic Pathogen Lipid Transport and Clearance.Am J Respir Crit Care Med2015
26426779Is genomic medicine finally coming of age for the diagnosis of pneumonia?Am J Respir Crit Care Med2015
26106080Treating the Host Response to Ebola Virus Disease with Generic Statins and Angiotensin Receptor Blockers.mBio2015
  • 1 - 50 of 317

Recommended Authors

University Hospital RWTH Aachen
Career Start Year 2013
Number of shared co-authors 0
Rainbow Babies and Children's Hospital
Career Start Year 2012
Number of shared co-authors 4
Location University of Amsterdam
Career Start Year 2011
Number of shared co-authors 16
LSU Health Sciences Center/Our Lady of the Lake Regional Medical Center
Career Start Year 2009
Number of shared co-authors 5
The Dental College of Georgia, Augusta University
Career Start Year 2008
Number of shared co-authors 0
Cardiovascular Research Institute, University of California san francisco
Career Start Year 2006
Number of shared co-authors 18
Ohio State University Wexner Medical Center
Career Start Year 2006
Number of shared co-authors 11
Uppsala University
Career Start Year 2004
Number of shared co-authors 2
Edouard Herriot Hospital
Career Start Year 2004
Number of shared co-authors 15
university of california san diego Department of Anesthesiology
Career Start Year 2003
Number of shared co-authors 1
University of Sydney Nepean Clinical School, Nepean Hospital
Career Start Year 2003
Number of shared co-authors 21
Centre Hospitalier Regional Universitaire (CHRU)
Career Start Year 2002
Number of shared co-authors 7
University of Michigan ann arbor
Career Start Year 2002
Number of shared co-authors 11
Massachusetts General Hospital
Career Start Year 2001
Number of shared co-authors 10
Hospital Clinico San Carlos
Career Start Year 2000
Number of shared co-authors 2
Aneurin Bevan University Health Board
Career Start Year 2000
Number of shared co-authors 7
University of Iowa
Career Start Year 1999
Number of shared co-authors 1
Erasmus University Medical Center
Career Start Year 1998
Number of shared co-authors 20
Indiana University School of Medicine
Career Start Year 1997
Number of shared co-authors 1
Brigham and Women's Hospital
Career Start Year 1997
Number of shared co-authors 21
University of Florida Health
Career Start Year 1997
Number of shared co-authors 13
University of Cincinnati College of Medicine
Career Start Year 1993
Number of shared co-authors 32
University of Kansas Medical Center
Career Start Year 1989
Number of shared co-authors 21
University of Michigan ann arbor
Career Start Year 1987
Number of shared co-authors 11
University of Washington
Career Start Year 1986
Number of shared co-authors 7
Clinical Center, National Institutes of Health
Career Start Year 1984
Number of shared co-authors 6
Vanderbilt University
Career Start Year 1984
Number of shared co-authors 13
Virginia Commonwealth University
Career Start Year 1978
Number of shared co-authors 10
Uniformed Services University of the Health Sciences
Career Start Year 1977
Number of shared co-authors 26
Massachusetts General Hospital
Career Start Year 1974
Number of shared co-authors 2

Collaborators

Erasme Hospital, Universite Libre de Bruxelles
Co-authored papers 24
University of Pittsburgh Medical Center
Co-authored papers 16
St. Michael's Hospital
Co-authored papers 12
Center for Experimental and Molecular Medicine, University of Amsterdam
Co-authored papers 11
Centre Hospitalier Regional Mons-Hainaut
Co-authored papers 9
Co-authored papers 8
Universite Paris Descartes
Co-authored papers 6
Kent County Hospital
Co-authored papers 6
University of Florida College of Medicine.
Co-authored papers 5
St. Paul's Hospital, University of British Columbia
Co-authored papers 4
National Institute of Allergy and Infectious Diseases
Co-authored papers 4
University of Kansas Medical Center
Co-authored papers 3
St. Michael's Hospital, University of Toronto
Co-authored papers 3
The George Institute for Global Health
Co-authored papers 3
University of Pittsburgh School of Medicine
Co-authored papers 3
Institute of Health Carlos III
Co-authored papers 3
Vanderbilt University
Co-authored papers 3
University of Nebraska School of Medicine
Co-authored papers 3
Northwestern University Feinberg School of Medicine
Co-authored papers 3
University of Pittsburgh School of Medicine
Co-authored papers 3
Emory University School of Medicine
Co-authored papers 3
Howard Levy Consulting LLC
Co-authored papers 3
Emory University
Co-authored papers 2
Harbor-university of california los angeles Medical Center
Co-authored papers 2
Eastern Idaho Regional Medical Center
Co-authored papers 2
Radboud University Medical Centre
Co-authored papers 2
UPMC Children's Hospital of Pittsburgh, University of Pittsburgh
Co-authored papers 2
University of Helsinki and Helsinki University Hospital
Co-authored papers 2
Clinical Research, University of Pittsburgh
Co-authored papers 2
Massachusetts General Hospital
Co-authored papers 2