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Author Details

Sue-Ann Mok
University of Alberta
2007
26
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37095396Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.Nat Neurosci2023
37961627DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.Res Sq2023
37961594DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.bioRxiv2023
37745431Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.bioRxiv2023
38054595Disease-Associated Mutations in Tau Encode for Changes in Aggregate Structure Conformation.ACS Chem Neurosci2023
35063084Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.Cell2022
35413950Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.Nat Commun2022
34234816Deciphering Network Crosstalk: The Current Status and Potential of miRNA Regulatory Networks on the HSP40 Molecular Chaperone Network.Front Genet2021
33547632Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability.Cell Stress Chaperones2021
34503506Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope.BMC Biol2021
33121065Prion-Like Propagation Mechanisms in Tauopathies and Traumatic Brain Injury: Challenges and Prospects.Biomolecules2020
31906970Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.Mol Neurodegener2020
31542321Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.Neuron2019
31578281Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation.J Biol Chem2019
29540553SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.J Neurosci2018
30385828Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau.Nat Commun2018
28159830Therapeutic Strategies for Restoring Tau Homeostasis.Cold Spring Harb Perspect Med2018
29728653Mapping interactions with the chaperone network reveals factors that protect against tau aggregation.Nat Struct Mol Biol2018
27884606BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins.J Mol Biol2017
28339398N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion.J Huntingtons Dis2017
26390242Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.Nat Med2015
24636344High-throughput screen of natural product extracts in a yeast model of polyglutamine proteotoxicity.Chem Biol Drug Des2014
23348044A HaloTag® method for assessing the retrograde axonal transport of the p75 neurotrophin receptor and other proteins in compartmented cultures of rat sympathetic neurons.J Neurosci Methods2013
19188931A retrograde apoptotic signal originating in NGF-deprived distal axons of rat sympathetic neurons in compartmented cultures.Cell Res2009
20010935Production of compartmented cultures of rat sympathetic neurons.Nat Protoc2009
16949623A nerve growth factor-induced retrograde survival signal mediated by mechanisms downstream of TrkA.Neuropharmacology2007
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Collaborators

Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 12
Li Gan
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 4
Tara E Tracy
Buck Institute for Research on Aging
Co-authored papers 4
Shiaoching Gong
Rockefeller University
Co-authored papers 4
Yaqiao Li
Harvard Medical School
Co-authored papers 4
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Gladstone Institutes
Co-authored papers 4
Chao Wang
Gladstone Institutes
Co-authored papers 4
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School of Clinical Medicine, University of Hong Kong
Co-authored papers 3
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Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 3
Sang-Won Min
Gladstone Institutes
Co-authored papers 3
Daniel R Southworth
The Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 3
Xu Chen
Gladstone Institutes
Co-authored papers 3
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 3
Yungui Zhou
Gladstone Institutes
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Carlo Condello
UCSF Weill Institute for Neurosciences, University of California san francisco
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Buck Institute for Research on Aging
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Wenjie Luo
Feil Family Brain and Mind Research Institute
Co-authored papers 2
Bruce L Miller
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 2
Virginia M-Y Lee
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 2
Eliezer Masliah
National Institute On Aging
Co-authored papers 2
Ana Maria Cuervo
Albert Einstein College of Medicine
Co-authored papers 2
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 2
Lauren Sweetland-Martin
Co-authored papers 1
Jordie Martin
Gladstone Institutes
Co-authored papers 1
Timothy S Chang
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1
Ruth H??ttenhain
Quantitative Biosciences Institute (QBI), University of California san francisco
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Li Gan
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Birgit Schilling
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Michael Gill
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