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Author Details

Igor Stagljar
University of Toronto, Canada Mediterranean Institute for Life Sciences
1993
141
46
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37225985Selective control of parasitic nematodes using bioactivated nematicides.Nature2023
37691145MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis.Cell Rep2023
37440478Identification and characterization of protein interactions with the major Niemann-Pick type C disease protein in yeast reveals pathways of therapeutic potential.Genetics2023
37100168Omicron Spike Protein is Vulnerable to Reduction.J Mol Biol2023
34426091Drugging the undruggable proteins in cancer: A systems biology approach.Curr Opin Chem Biol2022
36002479Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release.Commun Biol2022
36388990B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer.iScience2022
36344156The first 90 years of Ernesto Carafoli.Biochem Biophys Res Commun2022
35156780CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.Mol Syst Biol2022
35249128Met-HER3 crosstalk supports proliferation via MPZL3 in MET-amplified cancer cells.Cell Mol Life Sci2022
34896362D154Q Mutation does not Alter KRAS Dimerization.J Mol Biol2022
34079087Receptor tyrosine kinases and cancer: oncogenic mechanisms and therapeutic approaches.Oncogene2021
33795741Toward the discovery of biological functions associated with the mechanosensor Mtl1p of Saccharomyces cerevisiae via integrative multi-OMICs analysis.Sci Rep2021
33561544Distinct roles of UVRAG and EGFR signaling in skeletal muscle homeostasis.Mol Metab2021
33753733A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies.Nat Commun2021
34606829Mapping the Phospho-dependent ALK Interactome to Identify Novel Components in ALK Signaling.J Mol Biol2021
34662547Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.J Mol Biol2021
32415080Split Intein-Mediated Protein Ligation for detecting protein-protein interactions and their inhibition.Nat Commun2020
31668799Highly Combinatorial Genetic Interaction Analysis Reveals a Multi-Drug Transporter Influence Network.Cell Syst2020
32075961REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.Nat Commun2020
32094923A drug discovery platform to identify compounds that inhibit EGFR triple mutants.Nat Chem Biol2020
31980649Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS<sup>G13D</sup>.Nat Commun2020
32641451Protein Interactions of the Mechanosensory Proteins Wsc2 and Wsc3 for Stress Resistance in <i>Saccharomyces cerevisiae</i>.G3 (Bethesda)2020
30969105A Multireporter Bacterial 2-Hybrid Assay for the High-Throughput and Dynamic Assay of PDZ Domain-Peptide Interactions.ACS Synth Biol2019
31761084Highlights for the 60th anniversary of BBRC.Biochem Biophys Res Commun2019
30733383Identification and Functional Testing of Novel Interacting Protein Partners for the Stress Sensors Wsc1p and Mid2p of <i>Saccharomyces cerevisiae</i>.G3 (Bethesda)2019
29403380Recent Progress in CFTR Interactome Mapping and Its Importance for Cystic Fibrosis.Front Pharmacol2018
30125328SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue.PLoS Pathog2018
30043140Melatonin receptors limit dopamine reuptake by regulating dopamine transporter cell-surface exposure.Cell Mol Life Sci2018
30936440Testing cancer inhibitors at scale.Nat Biomed Eng2018
29659649Systems analysis of the genetic interaction network of yeast molecular chaperones.Mol Omics2018
27956147Systematic Identification of Oncogenic EGFR Interaction Partners.J Mol Biol2017
28253435Detecting Membrane Protein-protein Interactions Using the Mammalian Membrane Two-hybrid (MaMTH) Assay.Curr Protoc Chem Biol2017
28298427Systematic protein-protein interaction mapping for clinically relevant human GPCRs.Mol Syst Biol2017
28616575Multiple functions of protein phosphatases in receptor tyrosine kinase signaling revealed by interactome analysis.Mol Cell Oncol2017
28903051Features of the Chaperone Cellular Network Revealed through Systematic Interaction Mapping.Cell Rep2017
28931009NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation.PLoS One2017
28842709The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A<sub>2A</sub> receptor controlling its cell surface expression and function in vivo.Sci Rep2017
28007645Parkinson's disease-associated GPR37 receptor regulates cocaine-mediated synaptic depression in corticostriatal synapses.Neurosci Lett2017
28065597A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.Mol Cell2017
26921299Novel Interactome of Saccharomyces cerevisiae Myosin Type II Identified by a Modified Integrated Membrane Yeast Two-Hybrid (iMYTH) Screen.G3 (Bethesda)2016
26514267Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.J Pineal Res2016
27663662The power of OMICs.Biochem Biophys Res Commun2016
27708008A global genetic interaction network maps a wiring diagram of cellular function.Science2016
27009875Novel regulation of equlibrative nucleoside transporter 1 (ENT1) by receptor-stimulated Ca2+-dependent calmodulin binding.Am J Physiol Cell Physiol2016
27107012Pooled-matrix protein interaction screens using Barcode Fusion Genetics.Mol Syst Biol2016
26729912Membrane Yeast Two-Hybrid (MYTH) Mapping of Full-Length Membrane Protein Interactions.Cold Spring Harb Protoc2016
26729908MYTH Screening: iMYTH and tMYTH Variants.Cold Spring Harb Protoc2016
26729907Generation and Validation of MYTH Baits: iMYTH and tMYTH Variants.Cold Spring Harb Protoc2016
25402006In silico prediction of physical protein interactions and characterization of interactome orphans.Nat Methods2015
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Collaborators

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Schroeder Arthritis Institute
Co-authored papers 14
Mohan Babu
University of Regina
Co-authored papers 14
Max Kotlyar
Schroeder Arthritis Institute
Co-authored papers 12
Matthew Jessulat
University of Regina
Co-authored papers 7
Bernhard Suter
Baylor College of Medicine
Co-authored papers 6
Hiroyuki Aoki
University of Regina
Co-authored papers 5
Zoran Minic
University of Ottawa
Co-authored papers 4
Sadhna Phanse
University of Regina
Co-authored papers 4
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 4
Viktor Deineko
University of Northern British Columbia
Co-authored papers 4
Zhaolei Zhang
University of Toronto
Co-authored papers 3
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University Health Network, University of Toronto
Co-authored papers 3
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Boston University School of Medicine, Boston University
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Anne-Claude Gingras
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Co-authored papers 3
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University of Toronto
Co-authored papers 3
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Ontario Institute for Cancer Research, University Avenue
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Nozomu Yachie
The University of British Columbia
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Mandy H Y Lam
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 2
Michael Costanzo
Co-authored papers 2
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 2
Peter P Liu
Co-authored papers 2
Brigitte L Th??riault
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 2
Kevin R Brown
College Street, University of Toronto
Co-authored papers 2
Rima Al-Awar
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 2
James Vlasblom
University of Regina
Co-authored papers 2
Carles Pons
Co-authored papers 2
Dieter Egli
Co-authored papers 2
Ramy H Malty
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Co-authored papers 2
Release 1.2